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Maximizing Heterozygosity in Autopolyploids
1980Polyploidy appears dependent on heterozygosity! The largest group of polyploids, the allopolyploids (disomic polyploids), have fixed heterozygosity in the two or more divergent genomes they possess (e.g., wheat, oats, cotton, tobacco, etc.). Hexaploid wheat, for example, although self-pollinated and basically homozygous at loci in each of its three ...
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Outcrossing and heterozygosity
Advances in Applied Probability, 1974A classical question in population genetics is ‘In a species in which there is obligate outcrossing is there an increased amount of heterozygosity?’. This somewhat vague question can have two different meanings: (1) Is the number of alleles maintained at a locus greater?
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Loss of Heterozygosity in Endometrial Carcinoma
International Journal of Gynecological Pathology, 2008Inactivation of a tumor suppressor gene typically occurs in two steps, thus fulfilling Knudson hypothesis. One "hit" is frequently a point mutation or a small deletion. The other alteration is usually a large genomic loss of part of a gene, or even part of a chromosome, or the whole chromosome.
Ana, Velasco +9 more
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MHC heterozygosity and autoimmunity
Immunology Today, 1993M, Kimoto +3 more
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