Results 191 to 200 of about 30,028 (235)

Diet in Children Heterozygous for Familial Hypercholesterolemia

Archives of Pediatrics & Adolescent Medicine, 1977
Effects of a cholesterol- and saturate-poor, polyunsaturate-rich diet on plasma total and low-density lipoprotein (LDL) cholesterol levels were assessed in 23 children between the ages of 2 and 7 who were heterozygous for well-documented familial hypercholesterolemia.
C J, Glueck, R C, Tsang, R W, Fallat, M J, Mellies   +3 more
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Identification of people with heterozygous familial hypercholesterolemia

Current Opinion in Lipidology, 2012
Familial hypercholesterolemia is an underdiagnosed autosomal codominant genetic condition associated with significantly increased risk of early cardiovascular disease when untreated. Early diagnosis and treatment decrease the excess risk, and strategies for identification of affected individuals are being developed worldwide.
Annie, Haase, Anne C, Goldberg
openaire   +2 more sources

Effects of a low-fat dietary regimen enriched with soy in children affected with heterozygous familial hypercholesterolemia.

Clinical Nutrition ESPEN, 2020
INTRODUCTION Familial hypercholesterolemia (FH) is an inheritable, autosomal dominant disorder leading to pathologically increased levels of low-density-lipoprotein cholesterol (LDL-C).
O. Helk, K. Widhalm
semanticscholar   +1 more source

Children with Heterozygous Familial Hypercholesterolemia in the United States: Data from the CASCADE FH Registry.

Jornal de Pediatria, 2020
OBJECTIVE To describe enrollment characteristics of youth in the CAscade SCreening for Awareness and DEtection (CASCADE) Familial Hypercholesterolemia Registry. STUDY DESIGN Cross-sectional analysis of 493 participants
S. D. de Ferranti, P. Shrader, MacRae F. Linton, J. Knowles, L. Hudgins, I. Benuck, I. Kindt, Emily C. O'Brien, A. Peterson, Z. Ahmad, S. Clauss, P. Duell, M. Shapiro, K. Wilemon, S. Gidding, W. Neal   +15 more
semanticscholar   +1 more source

Serum apolipoproteins in heterozygous familial hypercholesterolemia

Clinica Chimica Acta, 1992
In order to characterize the abnormalities of the lipoprotein profile in familial hypercholesterolemia (FH), serum apolipoprotein AI, AII, B, CII, CIII, and E levels were determined by the turbidimetric immunoassay in 48 patients with heterozygous FH. Apolipoprotein B levels in FH were about 2.5 fold higher (203 +/- 48 mg/dl, mean +/- S.D.) than the 30
K, Kajinami, H, Mabuchi, J, Koizumi, R, Takeda   +3 more
openaire   +2 more sources

Coronary artery disease in heterozygous familial hypercholesterolemia

Atherosclerosis, 1982
Serum lipids, lipoproteins and Achilles tendon thickness in 52 patients with heterozygous familial hypercholesterolemia (FH) were investigated in order to clarify what are the important factors for the development of coronary artery disease (CAD) in heterozygous FH patients.
K, Hirobe, Y, Matsuzawa, K, Ishikawa, S, Tarui, A, Yamamoto, S, Nambu, K, Fujimoto   +6 more
openaire   +2 more sources

Evolocumab in Children with Heterozygous Familial Hypercholesterolemia

New England Journal of Medicine, 2020
Heterozygous familial hypercholesterolemia — in contrast to the more rare and more severe homozygous familial hypercholesterolemia — is a common genetic cholesterol disorder affecting approximately...
openaire   +2 more sources

Heterozygous familial hypercholesterolemia presenting as chylomicronemia syndrome

Journal of Clinical Lipidology, 2017
Heterozygous familial hypercholesterolemia (HeFH) is characterized by a twofold elevation in low-density lipoprotein cholesterol. Severe elevations in triglycerides are an uncommon manifestation. In this case report, we discuss an atypical presentation of the chylomicronemia syndrome in a patient with HeFH.
Robert S. Rosenson, Sherwin D. Najera, Robert A. Hegele   +2 more
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Adrenocortical Response to Adrenocorticotropin in Heterozygous Familial Hypercholesterolemia*

The Journal of Clinical Endocrinology & Metabolism, 1984
Receptor-mediated uptake of low density lipoproteins (LDL) provides an important source of cholesterol for corticosteroid synthesis by human adrenocortical cells grown in tissue culture. Recent studies have indicated an impaired adrenocortical response to prolonged ACTH stimulation in patients with abetalipoproteinemia (who lack plasma LDL) and in ...
D R, Illingworth, N A, Alam, S, Lindsey
openaire   +2 more sources

Impact of LDLR and PCSK9 pathogenic variants in Japanese heterozygous familial hypercholesterolemia patients.

Atherosclerosis, 2019
BACKGROUND AND AIMS More than 4970 variants in the low-density lipoprotein receptor (LDLR) gene and 350 variants in the proprotein convertase subtilisin/kexin 9 (PCSK9) gene have been reported in familial hypercholesterolemia (FH) patients.
M. Hori, Naotaka Ohta, A. Takahashi, H. Masuda, Rieko Isoda, Suguru Yamamoto, Cheol Son, M. Ogura, K. Hosoda, Y. Miyamoto, M. Harada‐Shiba   +10 more
semanticscholar   +1 more source