Results 91 to 100 of about 75,020 (311)
A Tabu Search Heuristic Procedure for the Capacitated Facility Location Problem [PDF]
A tabu search heuristic procedure for the capacitated facility location problem is developed, implemented and computationally tested. The heuristic procedure uses both short term and long term memories to perform the main search process as well as the ...
Minghe Sun
core
Advanced Science, EarlyView.SMarT‐Diff introduces a multi‐objective generative paradigm that integrates scaffold hopping with structure‐aware scoring to enable controlled exploration beyond the training distribution. The framework consistently balances drug‐likeness, synthesizes accessibility and bioactivity, yielding chemically diverse candidates with enhanced properties.
Yuwei Yang +8 more
wiley +1 more source
, 2013 Enhancing teamwork performance is a significant issue in mobile cloud-based learning. We introduce a service oriented system, Teamwork as a Service (TaaS), to realize a new approach for enhancing teamwork performance in the mobile cloud environment.
Jianming Yong +7 more
core +1 more source
AI‐Physics‐Experiment Trinity for Integrated Protein Dynamics Modeling
Advanced Science, EarlyView.This review unites experiments, physics‐based simulations, and AI as a synergistic triad for protein dynamics modeling. It highlights integrative strategies, resolves sampling and forcefield bottlenecks, and outlines challenges and future directions for accurate, interpretable conformational ensemble prediction.
Chen Shi +4 more
wiley +1 more source
A hybrid scatter search. Electromagnetism meta-heuristic for project scheduling. [PDF]
In the last few decades, several effective algorithms for solving the resource-constrained project scheduling problem have been proposed. However, the challenging nature of this problem, summarised in its strongly NP-hard status, restricts the ...
Debels, D +3 more
core
Hybrid meta-heuristic frameworks : a functional approach [PDF]
, 2013 Problems requiring combinatorial optimisation are routinely encountered in research and applied computing. Though polynomial-time algorithms are known for certain problems, formany practical problems, frommundane tasks in scheduling through to exotic ...
Senington, Richard James
core
Advanced Science, EarlyView.This paper illustrates a knowledge‐augmented dual‐track AI framework for advanced superalloy design. First, Large Language Models translate metallurgical heuristics into explicit rules to rapidly prune a vast compositional search space. Subsequently, LLM‐distilled priors safely guide a reinforcement learning agent during autonomous process optimization,
Jian Yao +9 more
wiley +1 more source
A comparative study of the Lasso-type and heuristic model selection methods [PDF]
This study presents a first comparative analysis of Lasso-type (Lasso, adaptive Lasso, elastic net) and heuristic subset selection methods. Although the Lasso has shown success in many situations, it has some limitations.
Ivan Savin
core
Heuristic Algorithms for the Maximum Colorful Subtree Problem [PDF]
, 2018 In metabolomics, small molecules are structurally elucidated using tandem mass spectrometry (MS/MS); this computational task can be formulated as the Maximum Colorful Subtree problem, which is NP-hard.
Lataretu, Marie A. +3 more
core +1 more source
Advanced Science, EarlyView.Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes +15 more
wiley +1 more source