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HEV Cell Culture

2016
Cell culture is an important research method in virology. Although many attempts have been conducted to culture HEV in cells, only a few cell culture systems were considered to be efficient enough for usage. Concentration of virus stocks, host cells, and medium components affects the culture efficiency and the genetic mutations during HEV passage were ...
Feng, Zhang, Youchun, Wang
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Immunobiology and Host Response to HEV

2023
Hepatitis E virus (HEV) usually causes acute self-limiting hepatitis but sometimes leads to chronic infection in immunocompromised persons. HEV is not directly cytopathic. Immunologically mediated events after HEV infection are believed to play important roles in the pathogenesis and clearance of infection.
Yi-Hua, Zhou, Hong, Zhao
openaire   +2 more sources

Epidemiology and genotypes of HEV in Wuhan

Chinese Journal of Digestive Diseases, 2005
BACKGROUND:  Understanding the genotype and clinical features of the hepatitis E virus (HEV) are important for understanding its characteristics, for evaluating region‐specific diagnostic assays, and producing vaccines.OBJECTIVES:  To investigate the epidemiology and the genotypes of HEV among outpatients and inpatients in the Department of Infectious ...
Yan, Chen, De Ying, Tian, Ning Shao, Xia
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Protective immunity against HEV

Current Opinion in Virology, 2014
Rural community of Dongtai City in eastern China is endemic for hepatitis E virus (HEV), with the zoonotic genotype 4 virus predominating. The virus appears to be widely distributed in environment at generally low levels, such that infection is common, but >97% of which are asymptomatic and provoke a modest antibody response.
Huang, Shou-Jie   +3 more
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Placenta as a site of HEV replication and inflammatory cytokines modulating the immunopathogenesis of HEV in pregnant women

Journal of Medical Virology, 2022
AbstractViral hepatitis E is an under‐estimated clinical entity with high mortality (20%–30%), especially in the third trimester of pregnancy. As complications due to hepatitis E virus (HEV) in pregnancy is much greater, it is hypothesized that HEV may cross the placenta and replicate in placental tissues even weeks after clearance from the blood, and ...
Radha Kanta Ratho   +5 more
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HEV and transfusion-recipient risk

Transfusion Clinique et Biologique, 2017
HEV infections are mainly food- and water-borne but transfusion-transmission has occurred in both developing and developed countries. The infection is usually asymptomatic but it can lead to fulminant hepatitis in patients with underlying liver disease and pregnant women living in developing countries.
J, Izopet   +5 more
openaire   +2 more sources

Characteristics and Functions of HEV Proteins

2016
Hepatitis E virus (HEV) is a non-enveloped virus containing a single-stranded, positive-sense RNA genome of 7.2 kb, which consists of a 5' non-coding region, three open reading frames (ORFs), and a 3' non-coding region. ORF1 is diverse between genotypes and encodes the nonstructural proteins, which include the enzymes needed for virus replication.
Yan, Zhou   +4 more
openaire   +3 more sources

Laboratory Diagnosis of HEV Infection

2016
Serological and nucleic acid tests for detecting hepatitis E virus (HEV) have been developed for both epidemiologic and diagnostic purposes. The laboratory diagnosis of HEV infection depends on the detection of HEV antigen or HEV RNA in the blood, stool, and other body fluids, and serum antibodies against HEV (immunoglobulin [Ig]A, IgM, and IgG).
Chenyan, Zhao, Youchun, Wang
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HEV systems

2001
Abstract When incorporating both of the ICE and electric motor, the vehicle is usually known as the hybrid EV (HEV). This HEV is actually not a new idea. A patent by Pieper in 1905 delineated that a battery-powered electric motor was used to boost the acceleration of an ICEV (Wouk, 1995; Bates, 1995). What exactly is a HEV?
C C Chan, K T Chau
openaire   +1 more source

HEV Powertrain Measurement

Vehicle Dynamics International, 2020
Glenn Wedgbrow, business development manager at Micro-Epsilon UK, discusses some of the more challenging test applications for hybrid and electric powertrains
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