Results 91 to 100 of about 32,578 (245)

BALB/c Mouse Is a Potential Animal Model System for Studying Acute and Chronic Genotype 4 Hepatitis E Virus Infection

Frontiers in Microbiology, 2020
Hepatitis E virus (HEV) is the main pathogen of hepatitis worldwide. However, its infection biology and pathogenesis remain largely unknown. Suitable small-animal models are required to advance the study of HEV infection.
Yunlong Li, Feiyan Long, Chenchen Yang, Xianhui Hao, Jian Wu, Jianwen Situ, Shuangfeng Chen, Zhongyao Qian, Fen Huang, Wenhai Yu   +9 more
doaj   +1 more source

Human IgE Antibodies Recognize the Vicilin and Alpha‐Hairpinin Domains of Peanut Allergen Ara h 1

Allergy, EarlyView.
The ɑ‐hairpinin of Ara h 1 contains a dominant epitope that is both frequently recognized and blocks a majority of the IgE against this domain. Including this region in tests may improve diagnosis of peanut allergy. The trimeric structure of the vicilin region explains the ability of Ara h 1 to induce anaphylaxis with a single antibody.
Taylor M. Cosey, Gage O. Leighton, Emmanuel R. De Diavoukana, Min Shi, Alexander C. Y. Foo, Anna Pomés, Jacqueline B. Nesbit, Stephen A. Y. Gipson, Paige Creeks, Jian Zhang, R. Stokes Peebles, Soheila J. Maleki, Derek Croote, Scott A. Smith, Geoffrey A. Mueller   +14 more
wiley   +1 more source

Structure of the m102.3/HeV-G complex, and comparison to the ephrin-B2/HeV-G structure.

, 2013
A. Left: Overall Structure of the m102.3/HeV-G complex viewed from the side. CDR-H3 (magenta) of m102.3 inserts into the central cavity of HeV-G (green). Disulfide bonds are shown as yellow sticks.
Dimitar B. Nikolov (122940), Kai Xu (122914), Vishwesh Mokashi (469190), Deborah L. Fusco (469189), Barry Rockx (151946), Kimberly A. Bishop-Lilly (123055), Blair L. DeBuysscher (102348), Yihu Xie (469188), Christopher C. Broder (122935), Yee-Peng Chan (122917), Regina Z. Cer (463681), Yan Xu (14594), Truong Luu (123134), Heinz Feldmann (18301), Zhongyu Zhu (360836), Dimiter S. Dimitrov (308439)   +15 more
core   +1 more source

Seroprevalence characteristics of hepatitis E virus among blood donors infected with hepatitis B virus

Zhongguo shuxue zazhi
[Objective] To investigate the seroprevalence characteristics of hepatitis E virus (HEV) among blood donors with hepatitis B virus (HBV) infection, so as to provide data support for the monitoring, prevention and treatment of HEV.
YU Qin, XU Tingting, YANG Hao, ZHAO Lei
doaj   +1 more source

Father–Son Comparison of Reproductive Traits

Andrology, EarlyView.
ABSTRACT Background Little is known about the relative contribution of genetic and environmental factors on male reproductive function. Objectives We studied in a cross‐sectional setting, whether testicular function and genital size correlate in father–son pairs.
Heidi Elamo, Wiwat Rodprasert, Louise Scheutz Henriksen, Niels Jørgensen, Niels E. Skakkebaek, Anders Juul, Helena Ollila, Katharina M. Main, Jorma Toppari, Helena E. Virtanen   +9 more
wiley   +1 more source

Periodontitis‐Associated Circulating EVs Promote Colorectal Cancer Progression via Carnosine‐Mediated Acidosis Adaptation

Cell Proliferation, EarlyView.
This study identifies a link between periodontitis and CRC progression mediated by carnosine‐enriched circulating EVs. These EVs target the intestine and elevate tumour cell intracellular pH (pHi), which rescues lysosomal function. This process drives a transition from dysfunctional lysosomes to functional ones, promoting a high malignancy phenotype in
Ruoyi Wu, Zihan Cai, Hualing Sun, Haikun Yu, Bicheng Zhang, Chi Zhang, Yi Fan, Xiaoxuan Zhu, Yueqi Ni, Yu Cui, Kaixin Wang, Zhe Li, Xinyi Zhou, Qing He, Yanru Wu, Yufeng Zhang   +15 more
wiley   +1 more source

Laboratuvar Hayvanlarında Tarama Programlarının Önemi ve Bazı Önemli Viral Ajanların Araştırılması

Laboratuvar Hayvanları Bilimi ve Uygulamaları Dergisi
Laboratuvar hayvanlarının sağlık tarama programları, biyomedikal araştırmalarda standardizasyonun sağlanması ve hem hayvanların hem de araştırma personelinin sağlığının korunması açısından büyük önem taşımaktadır.
Sebahattin Akça, Hayrunnisa Bostan Yörü, Yasin Kalay, Erdal Polat   +3 more
doaj   +1 more source

Rapid maternal death surveillance and response during a hepatitis E virus outbreak in Madani, Al Jazera state, Sudan

International Journal of Gynecology &Obstetrics, EarlyView.
Mawda Alshaarany, Benjamin Black, Gillian Burkhadt, Noor Rijnberg, Abrar Abdelsalam Zakria Sharif, Maura Daly, Gautam Harigovind, Ali Almohammed   +7 more
wiley   +1 more source

Liver Organoids: From Disease Modelling to Regenerative Medicine

Cell Proliferation, EarlyView.
Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang, Xiaotian Qu, Jinhong Si, Junkang Meng, Ting Zhang, Shuliang Niu   +5 more
wiley   +1 more source

Neurological manifestation of HEV infection: still a rare disease entity?

, 2023
Hepatitis E virus (HEV) infection is the most common form of viral hepatitis and is reported to cause neurological manifestation in up to 30% of diagnosed infections.
Tumani, Hayrettin, Zizer, Eugen, Wiesenfarth, Maximilian, Ludolph, Albert C., Stamminger, Thomas   +4 more
core   +1 more source