Management of Hepatitis E Virus (HEV) Zoonotic Transmission: Protection of Rabbits against HEV Challenge following Immunization with HEV 239 Vaccine [PDF]
Hepatitis E virus (HEV) constitutes a significant health burden worldwide, with an estimated approximately 33% of the world's population exposed to the pathogen. The recent licensed HEV 239 vaccine in China showed excellent protective efficacy against HEV of genotypes 1 and 4 in the general population and pregnant women.
Peng Liu +8 more
openaire +5 more sources
Identification of a putative novel genotype 3/rabbit hepatitis E virus (HEV) recombinant. [PDF]
Hepatitis E virus (HEV) is a viral pathogen transmitted by the fecal-oral route and is a major cause of waterborne acute hepatitis in many developing countries.
Ka-Cheung Luk +3 more
doaj +2 more sources
Hepatitis E Virus (HEV) Infection Among Immunocompromised Individuals: A Brief Narrative Review
Radostina Alexandrova,1 Ilia Tsachev,2 Plamen Kirov,1 Abedulkadir Abudalleh,1 Hristo Hristov,1 Tanya Zhivkova,1 Lora Dyakova,3 Magdalena Baymakova4 1Department of Pathology, Institute of Experimental Morphology, Pathology and Anthropology with Museum ...
Alexandrova R +7 more
doaj +1 more source
Reversing Macrophage Immunometabolic Dysfunction in Prolonged Infections Via a Glutaminolysis-Fueled Restoration-Based Hierarchically Selective Therapeutic System. [PDF]
A hierarchically selective immunotherapeutic nanoplatform, mGls@HEV‐MTP, selectively restores macrophage immunocompetence through GLS1‐mediated restoration of glutaminolysis‐fueled anaplerosis. Concurrently, it renders Staphylococcus aureus (S. aureus) more readily recognizable to the metabolically reprogrammed macrophages, thereby facilitating ...
Yang W +17 more
europepmc +2 more sources
Hev b 1, Hev b 2 and Hev b 3 content in natural rubber latex and latex gloves
Contact with latex gloves or powder from the gloves can induce an allergic reaction in sensitized persons. Although eleven latex allergens (Hev b 1 to Hev b 11) have been identified, there have been few reports on the levels of the specific allergens present in latex gloves.
Yeang, Hoong Yeet +6 more
openaire +2 more sources
Anti-HEV seroprevalence and rate of viremia in a German cohort of dogs, cats, and horses [PDF]
Hepatitis E virus (HEV) genotype 3 infections in Germany are mainly transmitted zoonotically through the consumption of swine meat. Furthermore, there is evidence that pets might come into contact with HEV, but the relevance of companion animals as ...
M. Mader +32 more
core +1 more source
High Hepatitis E Virus (HEV) Seroprevalence and No Evidence of HEV Viraemia in Vietnamese Blood Donors [PDF]
The prevalence of hepatitis E virus (HEV) in the Vietnamese population remains underestimated. The aim of the present study was to investigate the seroprevalence of HEV IgG/IgM antibodies and the presence of HEV RNA in blood donors as a part of ...
Ngo Thi Minh Chau +27 more
core +1 more source
Assessment of the cross-protective capability of recombinant capsid proteins derived from pig, rat, and avian hepatitis E viruses (HEV) against challenge with a genotype 3 HEV in pigs [PDF]
Hepatitis E virus (HEV), the causative agent of hepatitis E, is primarily transmitted via the fecal-oral route through contaminated water supplies, although many sporadic cases of hepatitis E are transmitted zoonotically via direct contact with infected ...
Meng, Xiang-Jin +5 more
core +1 more source
Rescue of a genotype 4 human hepatitis E virus from cloned cDNA and characterization of intergenotypic chimeric viruses in cultured human liver cells and in pigs [PDF]
Hepatitis E virus (HEV) is an important but extremely understudied human pathogen. Genotypes 1 and 2 are restricted to humans, whereas genotypes 3 and 4 are zoonotic, infecting both humans and pigs.
Meng, Xiang-Jin +6 more
core +1 more source
First isolation of Hepatitis E virus genotype 4 in Europe through swine surveillance in the Netherlands and Belgium. [PDF]
Hepatitis E virus (HEV) genotypes 3 and 4 are a cause of human hepatitis and swine are considered the main reservoir. To study the HEV prevalence and characterize circulating HEV strains, fecal samples from swine in the Netherlands and Belgium were ...
Coillie, E., Van +14 more
core +2 more sources

