Results 61 to 70 of about 17,549 (208)

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

VIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore, Beatrice Pellegrini, Antonia Mancuso, Maria Chiara Cristiano, Salvatore Panza, Donatella Paolino   +5 more
wiley   +1 more source

The HEV Ventilator Proposal

, 2020
We propose the design of a ventilator which can be easily manufactured and integrated into the hospital environment to support COVID-19 patients. The unit is designed to support standard ventilator modes of operation, most importantly PRVC (Pressure Regulated Volume Control) and SIMV-PC (Synchronised Intermittent Mandatory Ventilation) modes.
Buytaert, J., Abud, A. Abed, Akiba, K., Bay, A., Bertella, C., Bowcock, T., Byczynski, W., Coco, V., Collins, P., Francisco, O. Augusto De Aguiar, Dikic, N., Dumps, R., Durante, P., Prieto, A. Fernández, Lima, V. Franco, Guida, R., Hennessy, K., Hutchcroft, D., Ilic, S., Jevtic, A., Kapusniak, K., Cid, E. Lemos, Lindner, J., Milovanovic, M., Murray, D., Nasteva, I., Neufeld, N., Pons, X., Sanders, F., Schwemmer, R., Svihra, P.   +30 more
openaire   +2 more sources

Father–Son Comparison of Reproductive Traits

Andrology, EarlyView.
ABSTRACT Background Little is known about the relative contribution of genetic and environmental factors on male reproductive function. Objectives We studied in a cross‐sectional setting, whether testicular function and genital size correlate in father–son pairs.
Heidi Elamo, Wiwat Rodprasert, Louise Scheutz Henriksen, Niels Jørgensen, Niels E. Skakkebaek, Anders Juul, Helena Ollila, Katharina M. Main, Jorma Toppari, Helena E. Virtanen   +9 more
wiley   +1 more source

BALB/c Mouse Is a Potential Animal Model System for Studying Acute and Chronic Genotype 4 Hepatitis E Virus Infection

Frontiers in Microbiology, 2020
Hepatitis E virus (HEV) is the main pathogen of hepatitis worldwide. However, its infection biology and pathogenesis remain largely unknown. Suitable small-animal models are required to advance the study of HEV infection.
Yunlong Li, Feiyan Long, Chenchen Yang, Xianhui Hao, Jian Wu, Jianwen Situ, Shuangfeng Chen, Zhongyao Qian, Fen Huang, Wenhai Yu   +9 more
doaj   +1 more source

Clinical Burden of Symptomatic HEV‐3 Infection in Southern Spain

Alimentary Pharmacology &Therapeutics, EarlyView.
Clinical burden of symptomatic HEV‐3 infection in southern Spain. Between 2022 and 2025, 1124 patients with acute hepatitis, defined as ALT ≥ 3 times the upper limit of normal and negative screening for HAV, HBV, HCV, EBV and CMV, were evaluated in Andalusia.
María Casares‐Jimenez, Claudia Ferreira‐Tata, Isabel Viciana, Carolina Freyre‐Carrillo, Pedro Lopez‐Lopez, Ana Belen Perez, Berta Becerril‐Carral, Ana Fuentes, Juan Macías, Lucia Rios‐Muñoz, Francisco Franco‐Alvarez de Luna, María Teresa Cabezas‐Fernandez, Diana Corona‐Mata, Antonio Rivero‐Juarez, Antonio Rivero   +14 more
wiley   +1 more source

Periodontitis‐Associated Circulating EVs Promote Colorectal Cancer Progression via Carnosine‐Mediated Acidosis Adaptation

Cell Proliferation, EarlyView.
This study identifies a link between periodontitis and CRC progression mediated by carnosine‐enriched circulating EVs. These EVs target the intestine and elevate tumour cell intracellular pH (pHi), which rescues lysosomal function. This process drives a transition from dysfunctional lysosomes to functional ones, promoting a high malignancy phenotype in
Ruoyi Wu, Zihan Cai, Hualing Sun, Haikun Yu, Bicheng Zhang, Chi Zhang, Yi Fan, Xiaoxuan Zhu, Yueqi Ni, Yu Cui, Kaixin Wang, Zhe Li, Xinyi Zhou, Qing He, Yanru Wu, Yufeng Zhang   +15 more
wiley   +1 more source

Seroprevalence characteristics of hepatitis E virus among blood donors infected with hepatitis B virus

Zhongguo shuxue zazhi
[Objective] To investigate the seroprevalence characteristics of hepatitis E virus (HEV) among blood donors with hepatitis B virus (HBV) infection, so as to provide data support for the monitoring, prevention and treatment of HEV.
YU Qin, XU Tingting, YANG Hao, ZHAO Lei
doaj   +1 more source

Liver Organoids: From Disease Modelling to Regenerative Medicine

Cell Proliferation, EarlyView.
Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang, Xiaotian Qu, Jinhong Si, Junkang Meng, Ting Zhang, Shuliang Niu   +5 more
wiley   +1 more source

Rapid maternal death surveillance and response during a hepatitis E virus outbreak in Madani, Al Jazera state, Sudan

International Journal of Gynecology &Obstetrics, EarlyView.
Mawda Alshaarany, Benjamin Black, Gillian Burkhadt, Noor Rijnberg, Abrar Abdelsalam Zakria Sharif, Maura Daly, Gautam Harigovind, Ali Almohammed   +7 more
wiley   +1 more source

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source