Results 51 to 60 of about 1,761 (159)

Role of hydrogen bonding in conformational energies of hexachlorophene and its derivatives - A theoretical study [PDF]

, 2018
643-648Conformational space around two dihedral angles (viz., θ and φ) in hexachlorophene (HCP), dimethylhexachlorophene (DMHCP) and diphenylhexachlorophene (DPHCP), has been scanned at the AM1 level and further the minima optimized at DFT(B3LYP)/ 6-31G ...
Akilandeswari, L, Prathipa, C, Kalpana, P   +2 more
core  

Review of the role of biofilms in equine wounds: Clinical indications and treatment strategies

Equine Veterinary Education, Volume 36, Issue 3, Page 152-168, March 2024.
Summary Recognition of the role that biofilms play in the persistence of wounds and lack of response to therapy in horses is increasing. Prevention of biofilm development in the early stages of wound care involves three primary strategies: wound debridement and cleansing to reduce bacterial counts in the wound bed, appropriate use of advanced wound ...
Kara Marchant, Dean A. Hendrickson, Lynn M. Pezzanite   +2 more
wiley   +1 more source

Apicoplast‐Resident Processes: Exploiting the Chink in the Armour of Plasmodium falciparum Parasites

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2024, Issue 1, 2024.
The discovery of a relict plastid, also known as an apicoplast (apicomplexan plastid), that houses housekeeping processes and metabolic pathways critical to Plasmodium parasites’ survival has prompted increased research on identifying potent inhibitors that can impinge on apicoplast‐localised processes.
Collins Ojonugwa Mamudu, Mercy Eyitomi Tebamifor, Mary Ohunene Sule, Titilope Modupe Dokunmu, Olubanke Olujoke Ogunlana, Franklyn Nonso Iheagwam, Parasuraman Pavadai   +6 more
wiley   +1 more source

Prospective Investigation of Nasal Mupirocin, Hexachlorophene Body Wash, and Systemic Antibiotics for Prevention of Recurrent Community-Associated Methicillin-Resistant Staphylococcus aureus Infections

, 2012
Recurrent community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) skin infections are an increasingly common problem. However, there are no data on the efficacy of decolonization regimens.
Samantha J. Eells, Jennifer Tan, Allen B. Radner, Loren G. Miller, Esther Benitez   +4 more
core   +1 more source

The effects of hexachlorophene on mitochondrial and artificial membrane systems

Hexachlorophene (HCP; 2,2'-methylenebis-(3,4,6-trichlorophenol)) was developed as an antibacterial agent but was also found to induce toxic effects in various tissues in animals and humans. Changes were found in myelinated nerve fibers and cerebral white
Ramberg, Donald Allen
core   +4 more sources

Reversible and irreversible inhibitors of coronavirus Nsp15 endoribonuclease. [PDF]

J Biol Chem, 2023
Chen J, Farraj RA, Limonta D, Tabatabaei Dakhili SA, Kerek EM, Bhattacharya A, Reformat FM, Mabrouk OM, Brigant B, Pfeifer TA, McDermott MT, Ussher JR, Hobman TC, Glover JNM, Hubbard BP.   +14 more
europepmc   +1 more source

Antimicrobial and toxicological studies on an antiseptic based on hexachlorophene and destructive distillate of castor oil

, 1978
Bactericidal, bacteriostatic, fungistatic and toxicological evaluaton of an emulsion containing 0.25% hexachlorophene (W/V), 9.5% terpineol (V/V), 1.5% oil of terpentine (V/V), 13% ethanol (V/V), 6% castor oil distillate 1201275 degrees C (V/V) and 6 ...
Basit, N., Mahmood, I., Bukhari, A. Q., Siddiqui, M. A., Ahmed, S.   +4 more
core  

The sensitivity of the zebrafish embryo coiling assay for the detection of neurotoxicity by compounds with diverse modes of action. [PDF]

Environ Sci Pollut Res Int, 2023
von Hellfeld R, Gade C, Baumann L, Leist M, Braunbeck T.   +4 more
europepmc   +1 more source

An ELISA for discovering protein-protein interaction inhibitors: Blocking lysinoalanine crosslinking between subunits of the spirochete flagellar hook as a test case. [PDF]

SLAS Discov
Deshpande M, Lynch MJ, Kurniyati K, Li C, Crane BR.   +4 more
europepmc   +1 more source

Identification of Nsp15 inhibitors restoring interferon-dependent antiviral activity against SARS-CoV-2. [PDF]

Antiviral Res
Maloccu S, Otsuka Y, Molchan E, Foti M, Paulis A, Vishwakarma J, Malune P, Cottiglia F, Corona A, Scampavia L, Spicer TP, Harris RS, Tramontano E, Fanunza E.   +13 more
europepmc   +1 more source