Synthesis of 1,6-bis(semicarbazide)hexanes and 1,6-bis(1,2,4-triazol-5-one)hexanes and their antiproliferative and antimicrobial activity [PDF]
A series of 1,6-bis(3-substituted-4,5-dihydro-1H-1,2,4-triazol-5-on-4- yl)hexanes (3a-g) were synthesized by the cyclization reaction of 1,6-bis(1- substituted-semicarbazide-4-yl)hexanes (2a-g) in alkaline medium.
Pitucha M. +3 more
doaj +2 more sources
Enantioselective Synthesis of 2-Oxabicyclo[2.1.1]hexanes and Bicyclo[2.1.1]hexanes via Catalytic Asymmetric Intramolecular Photocycloadditions [PDF]
Due to the ubiquitous presence of ortho-disubstituted benzenes in pharmaceuticals and agrochemicals, the exploration of their bioisosteres incorporating three-dimensional bridged cyclic scaffolds has attracted significant interest among chemists in ...
Dong Tian +6 more
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THE SYNTHESIS AND CONFORMATIONAL ANALYSIS OF 1,5-DIAZABICYCLO(3.1.0) HEXANES.
THE SYNTHESIS AND CONFORMATIONAL ANALYSIS OF 1,5-DIAZABICYCLO(3.1.0 ...
HUEY PERRY. MALONE (7974716)
core +6 more sources
The practice of latent print analysis is comprised of a visual examination and the comparison of the fingerprint pattern from a questioned print to an exemplar(s).
Jessica Kindell, Candice Bridge
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1,2-Disubstituted Bicyclo[2.1.1]hexanes as Bioisosteres of the ortho-substituted Benzene [PDF]
1,2-Disubstitued bicyclo[2.1.1]hexanes have been designed, synthesized, and validated as a new generation of saturated bioisosteres of ortho-substituted benzenes. Incorporation of the bicyclo[2.1.1]hexane core into the structure of agrochemicals Boskalid
Iryna , Sadkova +8 more
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Catalytic borylations of sp3 C-H bonds occur with high selectivities for primary C-H bonds or secondary C-H bonds that are activated by nearby electron-withdrawing substituents. Catalytic borylation at tertiary C-H bonds has not been observed.
Pashenko, Alexander +17 more
core +1 more source
Determination of Organosulfides from Onion Oil
Qualitative and semi-quantitative analysis of organosulfides extracted from oil obtained by steam distillation of yellow onions was performed by gas chromatography-mass spectrometry (GC-MS).
Maranda S. Cantrell +3 more
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3-Azabicyclo[3.1.0]hexanes are common structural components in natural products and bioactive compounds. Traditionally, the metal-mediated cyclopropanation domino reaction of chain enzymes is the most commonly used strategy for the construction of this ...
Jingya Li +5 more
doaj +1 more source
Enantioselective photocatalytic synthesis of bicyclo[2.1.1]hexanes as orthodisubstituted benzene bioisosteres with improved biological activity [PDF]
1,5-Disubstituted bicyclo[2.1.1]hexanes are bridged scaffolds with well-defined exit vectors that are becoming increasingly popular building blocks in medicinal chemistry since they are saturated bioisosteres of orthosubstituted phenyl rings.
Israel , Fernandez +6 more
core +1 more source
Trimethyl 4,4′,4′′-(ethene-1,1,2-triyl)tribenzoate
The title compound, C26H22O6, is formed as the major product from the reaction between syn-1,2-bis(pinacolatoboron)-1,2-bis(4-methylcarboxyphenyl)ethene and excess methyl 4-iodobenzoate in basic DMSO using a palladium catalyst at 80°C via Suzuki coupling
Melvin J. G. Lesley +3 more
doaj +1 more source

