A Inibição do Metabolismo da Glicose por miR-34a e miR-125b Protege contra a Morte Celular de Cardiomiócitos Causada por Hiperglicemia [PDF]
Resumo Fundamento: É sabido que a resistência à insulina e a hiperglicemia são causas patológicas importantes no desenvolvimento de cardiomiopatia diabética (CMD).
Chao-rui Xu, Qiu-ju Fang
doaj +4 more sources
Purificação de hexoquinases de rim de coelho [PDF]
Rabbit kidney has been used as a source for the purification of hexokinases. Phosphorylation of glucose, fructose, mannose, and galactose were accomplished by crude extracts, and by partialy purified preparations obtained from acetone powders prepared from prefrozen kidneys.Hexokinase activity in rabbit tissues was assayed in kidney, heart, brain ...
Jaira Bele de Figueiredo +2 more
openaire +4 more sources
Chronic Hyperglycemia Modulates Rat Osteoporotic Cortical Bone Microarchitecture into Less Fragile Structures. [PDF]
There is controversy concerning the diabetes impact on bone quality, notorious in type 2 diabetic postmenopausal women. One pointed cause might be uncontrolled glycemia. In this study, the effect of chronic hyperglycemia in bone turnover, morphology, and biomechanics was evaluated in female Wistar rats in the presence/absence of estrogens (ovariectomy).
de Mello-Sampayo C +8 more
europepmc +2 more sources
Changes in trehalose content of baker's yeast as affected by octanoic acid Alterações no teor de trealose de levedura de panificação provocadas por ácido octanóico [PDF]
Octanoic acid inhibited ethanolic fermentation by Saccharomyces cerevisiae (bakers yeast) and the trehalose accumulation, however did not affect the endogenous degradation of trehalose.
L.E. Gutierrez
doaj +3 more sources
Purificação e caracterização da VDAC de mitocôndrias corticais aviares: identificação de modificações pós-traducionais nas porinas neuronais murinas e aviares [PDF]
A VDAC é uma porina presente na MME cuja função é crucial no metabolismo energético, sobrevivência e morte celular. A caracterização da VDAC torna-se importante para a compreensão das inter-relações da mitocôndria com os diferentes componentes ...
Phelipe Augusto Mariano Vitale +4 more
doaj +2 more sources
A VDAC é a proteína mais abundante na membrana mitocondrial externa. Exerce o controle da atividade desta organela através da regulação da troca de metabólitos e tem função crucial no mecanismo de apoptose.
Carla Rossini Crepaldi +3 more
doaj +1 more source
Chemotherapy of Chagas' disease: state of the art and perspectives for the development of new drugs [PDF]
Neglected diseases are a major global cause of illness, long-term disability and death. Chagas' disease is a parasitic infection widely distributed throughout Latin America, with devastating consequences in terms of human morbidity and mortality.
ANDRICOPULO, Adriano Defini +5 more
core +2 more sources
Analisou-se a influência exercida pelo tratamento hormonal substitutivo no metabolismo eritrocitário de 16 doentes com hipotiroidismo primário, estudados antes e durante terapêutica com tiroxina.
Carlota Proença +5 more
doaj +1 more source
The isoenzyme profiles (IP) of 33 strains of Entamoeba histolytica isolated from patients and carriers of two regions in Brazil (Amazonia and Southeast) were determined.
Ana Maria Barral de Martinez +4 more
doaj +1 more source
Red Wine Consumption Is Associated with Fecal Microbiota and Malondialdehyde in a Human Population [PDF]
[Objectives] Red wine intake has been associated with a lower risk of cardiovascular disease; its polyphenol content is the primary cause of antioxidant and anti-inflammatory properties attributed to this beverage.
Cuervo, Adriana +6 more
core +1 more source

