Results 1 to 10 of about 146,517 (120)
Recent advances in the use of liquid biopsy to fight central nervous system tumors
Cancer Treatment and Research Communications, 2023 Brain tumors are considered one of the deadliest types of cancer, being challenging to treat, especially due to the blood-brain barrier, which has been linked to treatment resistance.
Carlos Pilotto Heming +3 more
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Medicina, 2023 Different cancers have multiple genetic mutations, which vary depending on the affected tumour tissue. Small biopsies may not always represent all the genetic landscape of the tumour.
Veronica Aran +7 more
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The genotypic and phenotypic impact of hypoxia microenvironment on glioblastoma cell lines
BMC Cancer, 2021 Background Glioblastoma is a fatal brain tumour with a poor patient survival outcome. Hypoxia has been shown to reprogram cells towards a stem cell phenotype associated with self-renewal and drug resistance properties.
Lucy Wanjiku Macharia +9 more
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Case Report: Anomalous Experience in a Dissociative Identity and Borderline Personality Disorder
Frontiers in Psychiatry, 2022 IntroductionDissociative identity disorder, formerly called multiple personality disorder, is a rupture of identity characterized by the presence of two or more distinct personality states, described in some cultures as an experience of possession ...
Hugo André de Lima Martins +4 more
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Hepatology, EarlyView., 2022 Graphical abstract summarizing the study design, main results and key findings Abstract Background and Aims Fatty liver disease (FLD) has been associated with excess mortality. Screening for hepatic steatosis (HS) in patients with metabolic dysfunction is therefore recommended by several guidelines, despite a paucity of evidence on the clinical ...
Laurens A. van Kleef +5 more
wiley +1 more source
P-glycoprotein and cancer: what do we currently know?
Heliyon, 2022 Acquired resistance during cancer treatment is unfortunately a frequent event. There are several reasons for this, including the ability of the ATP-binding cassette transporters (ABC transporters), which are integral membrane proteins, to export ...
Carlos Pilotto Heming +5 more
doaj +1 more source
Psychosocial approach of epilepctic patients
Arquivos de Neuro-Psiquiatria, 1992 Psychosocial aspects of patient's life were analysed in 30 patients with epilepsy aged over 18 years old. At this age people usually are apt by themselves to exert several psychosocial activities.
N. O. Facure, C.m.b. Toniolo, M. Maeda
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Alois Alzheimer and vascular brain disease: Arteriosclerotic atrophy of the brain. [PDF]
, 2015 Alois Alzheimer is best known for his description of neurofibrillary changes in brain neurons of a demented patient, identifying a novel disease, soon named after him by Kraepelin.
Engelhardt, Eliasz, Grinberg, Lea T
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Gliomas and the vascular fragility of the blood brain barrier
Frontiers in Cellular Neuroscience, 2014 Astrocytes, members of the glial family, interact through the exchange of soluble factors or by directly contacting neurons and other brain cells, such as microglia and endothelial cells. Astrocytic projections interact with vessels and act as additional
Luiz Gustavo eDubois +15 more
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Medir o cérebro, para quê? [PDF]
, 2009 Várias são as “janelas” da Ressonância Magnética (RM) que hoje têm aplicação na clínica. Servem para fundamentar o diagnóstico (p.e., da encefalopatia microvascular do idoso), o prognóstico (p.e., do declínio cognitivo), a terapêutica (p.e., da ...
Marçalo, José +2 more
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