Results 11 to 20 of about 2,774 (172)

Differential response of chondrocytes and chondrogenic-induced mesenchymal stem cells to C1-OH tributanoylated N-acetylhexosamines. [PDF]

open access: yesPLoS ONE, 2013
Articular cartilage has a limited ability to self-repair because of its avascular nature and the low mitotic activity of the residing chondrocytes. There remains a significant need to develop therapeutic strategies to increase the regenerative capacity ...
Jeannine M Coburn   +5 more
doaj   +1 more source

Synthesis and in vitro cytotoxicity of acetylated 3-fluoro, 4-fluoro and 3,4-difluoro analogs of D-glucosamine and D-galactosamine

open access: yesBeilstein Journal of Organic Chemistry, 2016
Background: Derivatives of D-glucosamine and D-galactosamine represent an important family of the cell surface glycan components and their fluorinated analogs found use as metabolic inhibitors of complex glycan biosynthesis, or as probes for the study of
Štěpán Horník   +8 more
doaj   +1 more source

Synthesis of Hexosamine in the Rat

open access: yesExperimental Biology and Medicine, 1955
Summary1. The relationship of carcass hexosamine concentration to age in growing rats showed that a marked decrease occurs between 10 and 80 days of age. 2. Hexosamine synthesis within the rat was demonstrated by means of balance studies on fasted animals and on animals fed diets containing very small or moderate amounts of hexosamine.
J B, FOLEY, N F, BOAS
openaire   +2 more sources

Bioquímica e ação citotóxica de alfa-aminocetonas endógenas Biochemistry and cytotoxicity of alpha-aminoketones

open access: yesQuímica Nova, 2005
alpha-Aminoketones are expected to undergo enolization and subsequent aerobic oxidation yielding oxyradicals and highly toxic a-oxoaldehydes. Our interest has been focused on two endogenous a-aminoketones: 5-aminolevulinic acid (ALA) and aminoacetone (AA)
Fernando Dutra, Etelvino J. H. Bechara
doaj   +1 more source

Effect of Antiepileptic Drug Sodium Valproate on Stomach Tissue Glycoproteins: The Protective Role of Moringa Extract

open access: yesArchives of Epilepsy, 2023
Objective:Sialic acid, hexoses, hexosamines and fucose are components of glycoprotein, glycolipid and/or ganglioside. These glycoconjugates are essential components of cellular membrane and receptors, which are required for normal cellular activities ...
Umar Faruk Magaji   +3 more
doaj   +1 more source

Evidence that intracellular stages of Leishmania major utilize amino sugars as a major carbon source. [PDF]

open access: yesPLoS Pathogens, 2010
Intracellular parasites, such as Leishmania spp, must acquire suitable carbon sources from the host cell in order to replicate. Here we present evidence that intracellular amastigote stages of Leishmania exploit amino sugars in the phagolysosome of ...
Thomas Naderer   +2 more
doaj   +1 more source

Cytotoxicity and Glycan-Binding Properties of an 18 kDa Lectin Isolated from the Marine Sponge <em>Halichondria </em><em>o</em><em>kadai</em>

open access: yesToxins, 2012
A divalent cation-independent lectin—HOL-18, with cytotoxic activity against leukemia cells, was purified from a demosponge, <em>Halichondria okadai</em>. HOL-18 is a 72 kDa tetrameric lectin that consists of four non-covalently bonded 18 kDa
Yasuhiro Ozeki   +15 more
doaj   +1 more source

Features of Changes in Biochemical Parameters of Gastric Juice in Patients with Gastroesophageal Reflux Disease

open access: yesGastroenterologìa, 2016
There were studied the features of changes in the factors of aggression and protection in the gastric juice of 91 patients with gastroesophageal reflux disease (GERD) combined with sphincter of Oddi dysfunction. It was determined the pH, concentration of
L.M. Mosiichuk   +6 more
doaj   +1 more source

Disruption of O-GlcNAc cycling in C. elegans perturbs Nucleotide Sugar pools and Complex Glycans

open access: yesFrontiers in Endocrinology, 2014
The carbohydrate modification of serine and threonine residues with O-linked beta-N-acetylglucosamine (O-GlcNAc) is ubiquitous and governs cellular processes ranging from cell signaling to apoptosis.
Salil K Ghosh   +5 more
doaj   +1 more source

Pontiella desulfatans gen. nov., sp. nov., and Pontiella sulfatireligans sp. nov., Two Marine Anaerobes of the Pontiellaceae fam. nov. Producing Sulfated Glycosaminoglycan-like Exopolymers

open access: yesMicroorganisms, 2020
Recently, we isolated two marine strains, F1T and F21T, which together with Kiritimatiella glycovorans L21-Fru-ABT are the only pure cultures of the class Kiritimatiellae within the phylum Verrucomicrobiota.
Daan M. van Vliet   +6 more
doaj   +1 more source

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