Results 1 to 10 of about 26,061 (186)

Preparation, Physicochemical Characterization and Anti-Fungal Evaluation of Amphotericin B-Loaded PLGA-PEG-Galactosamine Nanoparticles [PDF]

Advanced Pharmaceutical Bulletin, 2021
Purpose: The present study aimed to formulate PLGA and PLGA-PEG-galactosamine nanoparticles (NPs) loaded with amphotericin B with appropriate physicochemical properties and antifungal activity.
Ghobad Mohammadi, Mostafa Fathian-Kolahkaj, Pardis Mohammadi, Khosro Adibkia, Ali Fattahi   +4 more
doaj   +1 more source

Divergent Accumulation of Microbial Residues and Amino Sugars in Loess Soil after Six Years of Different Inorganic Nitrogen Enrichment Scenarios

Applied Sciences, 2021
Amino sugars are key microbial biomarkers for determining the contribution of microbial residues in soil organic matter (SOM). However, it remains largely unclear as to what extent inorganic nitrogen (N) fertilization can lead to the significant ...
Dominic Kwadwo Anning, Zhilong Li, Huizhen Qiu, Delei Deng, Chunhong Zhang, Philip Ghanney, Qirong Shen   +6 more
doaj   +1 more source

Dynamics of Acute Liver Injury in Experimental Models of Hepatotoxicity in the Context of Their Implementation in Preclinical Studies on Stem Cell Therapy

Frontiers in Bioscience-Landmark, 2022
Background and Aims: Experimental models using carbon tetrachloride (CCl4) and D-galactosamine (D-GalN) can be used in preclinical assessment of acute liver failure (ALF) therapies.
Piotr Czekaj, Mateusz Król, Łukasz Limanówka, Aleksandra Skubis-Sikora, Emanuel Kolanko, Edyta Bogunia, Mateusz Hermyt, Marcin Michalik, Bartosz Sikora, Agnieszka Prusek, Aniela Grajoszek, Jacek Pająk   +11 more
doaj   +1 more source

Determination of glucosamine and galactosamine in food by liquid chromatography with pre-column derivatization

Food and Agricultural Immunology, 2022
A pre-column derivatization liquid chromatographic method was developed for the simultaneous determination of both glucosamine and galactosamine in selected food samples. The derivatization of glucosamine and galactosamine with 9-fluorenylmethoxycarbonyl
Li Mu, Ying Xu, Gang Li, Shuo Dai, Qi Tong, Bin Liu   +5 more
doaj   +1 more source

Crosstalk of TNF-α, IFN-γ, NF-kB, STAT1 and redox signaling in lipopolysaccharide/d-galactosamine/dimethylsulfoxide-induced fulminant hepatic failure in mice

Saudi Pharmaceutical Journal, 2023
Purpose: The clinical study of fulminant hepatic failure is challenging due to its high mortality and relative rarity, necessitating reliance on pre-clinical models to gain insight into its pathophysiology and develop potential therapies.
Abdulrazaq Alanazi, Mahmoud N. Nagi, Dhafer Y. Alhareth, Mohammed A Al-Hamamah, Mohamed A Mahmoud, Sheikh F. Ahmad, Mushtaq A. Ansari, Ahmed Nadeem, Saleh A. Bakheet, Gamaleldin I. Harisa, Sabry M. Attia   +10 more
doaj   +1 more source

Quantitative Analysis of Impurities in Unfractionated Heparin of Bovine Origin

Frontiers in Medicine, 2020
The USP heparin sodium monograph lists impurities with specifications developed for porcine derived products. Most of these impurities are of biological origin and are present in porcine intestinal mucosa, the tissue source used in the production of ...
Wesley E. Workman, Kevin L. Carrick
doaj   +1 more source

Susceptibility of Asialoglycoprotein Receptor-Deficient Mice to LPS/Galactosamine Liver Injury and Protection by Betaine Administration

Biology, 2020
Background: Work from our laboratory has shown that the ethanol-induced increase in apoptotic hepatocellular death is closely related to the impairment in the ability of the asialoglycoprotein receptor (ASGP-R) to remove neighboring apoptotic cells.
Karuna Rasineni, Serene M. L. Lee, Benita L. McVicker, Natalia A. Osna, Carol A. Casey, Kusum K. Kharbanda   +5 more
doaj   +1 more source

Evaluating the best time to intervene acute liver failure in rat models induced by d-galactosamine [PDF]

Acta Cirúrgica Brasileira, 2016
PURPOSE: To describe an animal model for acute liver failure by intraperitoneal d-galactosamine injections in rats and to define when is the best time to intervene through King's College and Clichy´s criteria evaluation.
Lígia Patrícia de Carvalho Batista Éboli, Alcides Augusto Salzedas Netto, Ramiro Antero de Azevedo, Valéria Pereira Lanzoni, Tatiana Sugayama de Paula, Alberto Goldenberg, Adriano Miziara Gonzalez   +6 more
doaj   +1 more source

Assembly of a Library of Pel-Oligosaccharides Featuring α-Glucosamine and α-Galactosamine Linkages

Frontiers in Chemistry, 2022
Pseudomonas aeruginosa, a pathogenic Gram-negative bacterium for which currently antibiotic resistance is posing a significant problem and for which no vaccines are available, protects itself by the formation of a biofilm.
Yongzhen Zhang, Liming Wang, Liming Wang, Herman S. Overkleeft, Gijsbert A. van der Marel, Jeroen D. C. Codée   +5 more
doaj   +1 more source

Spray-dried Centella asiatica ethanol extract preserves liver functions in Gal/LPS-induced hepatitis rats through anti-inflammatory and antioxidant properties [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: The hepatoprotective activity of Centella asiatica is very well described. However, it is often administered to the animals before prominent damage to the liver occurs.
Tri Yuliani, Indah D. Dewijanti, Marissa Angelina, Sofa Fajriah, Rizna T. Dewi, Gian Primahana, Ahmad Randy, Salsabila Fitriani, Yulvian Sani   +8 more
doaj   +1 more source