Results 21 to 30 of about 41,097 (233)

MAPK-activated protein kinase 2-deficiency causes hyperacute tumor necrosis factor-induced inflammatory shock [PDF]

open access: yes, 2014
Background: MAPK-activated protein kinase 2 (MK2) plays a pivotal role in the cell response to (inflammatory) stress. Among others, MK2 is known to be involved in the regulation of cytokine mRNA metabolism and regulation of actin cytoskeleton dynamics ...
Brouckaert, Peter   +5 more
core   +1 more source

Studies of liver phosphorylase in hepatic injuries. I. Alteration in enzyme activity [PDF]

open access: yes, 1978
Phosphorylase activities (total and a form) were determined in the livers of experimental hepatic injuries with carbon tetrachloride or galactosamine and the livers of patients with liver diseases.
Kobayashi, Michio
core   +1 more source

HPLC-PDA-MS/MS Characterization of Bioactive Secondary Metabolites from Turraea fischeri Bark Extract and Its Antioxidant and Hepatoprotective Activities In Vivo

open access: yesMolecules, 2017
Turraea fischeri is an East African traditional herb, which is widely used in traditional medicine. In this study, we profiled the secondary metabolites in the methanol extract of T.
Mansour Sobeh   +6 more
doaj   +1 more source

Phosphorylation of eIF2α mitigates endoplasmic reticulum stress and hepatocyte necroptosis in acute liver injury

open access: yesAnnals of Hepatology, 2020
Introduction and objectives: Necroptosis and endoplasmic reticulum (ER) stress has been implicated in acute and chronic liver injury. Activated eukaryotic initiation factor 2 alpha (eIF2α) attenuates protein synthesis and relieves the load of protein ...
Ren-Dong Tian   +10 more
doaj   +1 more source

Electric Method for the Desulfation of Polysaccharides From Red Microalgae (Porphyridium cruentum) Cultures. [PDF]

open access: yesBiopolymers
A non‐destructive method for depleting sulfates from the red microalgae Porphyridium cruentum by directly exposing the growth medium to a moderate electric field has been developed. The reported electric‐field separation method is a simple, straightforward, and non‐toxic means for the direct recovery of desulfated polysaccharides from P.
Levy-Ontman O   +7 more
europepmc   +2 more sources

The Emerging Role of Disturbed CoQ Metabolism in Nonalcoholic Fatty Liver Disease Development and Progression [PDF]

open access: yes, 2015
Although non-alcoholic fatty liver disease (NAFLD), characterised by the accumulation of triacylglycerol in the liver, is the most common liver disorder, the causes of its development and progression to the more serious non-alcoholic steatohepatitis ...
Elena Bravo   +3 more
core   +3 more sources

Succinate dehydrogenase inhibitor dimethyl malonate alleviates LPS/-galactosamine-induced acute hepatic damage in mice

open access: yesInnate Immunity, 2019
In addition to its energy-supplying function, increasing evidence suggests that mitochondria also play crucial roles in the regulation of inflammation.
Yongqiang Yang   +7 more
doaj   +1 more source

Definition of the Anti-inflammatory Oligosaccharides Derived From the Galactosaminogalactan (GAG) From Aspergillus fumigatus

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
Galactosaminogalactan (GAG) is an insoluble aminosugar polymer produced by Aspergillus fumigatus and has anti-inflammatory properties. Here, the minimum glycosidic sequences required for the induction of IL-1Ra by peripheral blood mononuclear cells ...
Markus Gressler   +13 more
doaj   +1 more source

Brevibacterium sandarakinum sp. nov., isolated from a wall of an indoor environment [PDF]

open access: yes, 2009
A Gram-stain-positive, rod-shaped, non-endospore-forming, orange-pigmented (coloured) actinobacterium (01-Je-003T) was isolated from the wall of an indoor environment primarily colonized with moulds.
Busse, Hans-Jürgen   +3 more
core   +1 more source

Correlation between synthesis of α2-macroglobulin as acute phase protein and degree of hepatopathy in rats

open access: yesLaboratory Animal Research, 2019
The degree of hepatopathy affecting the synthesis of α2-macroglobulin (α2M) as an acute phase protein in rats was investigated. Hepatopathy was induced in Sprague-Dawley rats by intravenous administration of galactosamine at a dose of 30 mg/kg for 7 days.
Reina Ito, Takashi Kuribayashi
doaj   +1 more source

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