Results 11 to 20 of about 26,061 (186)

The Therapeutic Efficacy of MS473, a Fully Human Single-Chain Variable Fragment Targeting Staphylococcus aureus Toxic Shock Syndrome Toxin-1, in a D-Galactosamine-Sensitized Mouse Model of Lethal Shock [PDF]

open access: yesBMC Microbiology
Toxic shock syndrome toxin-1 (TSST-1), produced by Staphylococcus aureus, is one of the most potent superantigens involved in causing life-threatening TSS and contributes to the onset of some autoimmune diseases.
Fatemeh Rahimi-Jamnani   +6 more
doaj   +2 more sources

Pathways for the utilization of N‐acetyl‐galactosamine and galactosamine in Escherichia coli [PDF]

open access: yesMolecular Microbiology, 2000
Among enteric bacteria, the ability to grow on N‐acetyl‐galactosamine (GalNAc or Aga) and on d‐galactosamine (GalN or Gam) differs. Thus, strains B, C and EC3132 of Escherichia coli are Aga+ Gam+ whereas E. coli K‐12 is Aga− Gam−, similarly to Klebsiella pneumoniae KAY2026, Klebsiella oxytoca M5a1 and Salmonella typhimurium LT2.
A, Brinkkötter   +3 more
openaire   +2 more sources

Enzymic phosphorylation of galactosamine and galactose [PDF]

open access: yesArchives of Biochemistry and Biophysics, 1953
Abstract The transfer of phosphate from adenosine triphosphate to galactosamine was found to be catalyzed by a liver enzyme. On the basis of the parallel distribution and from crossed inhibition experiments, it is suggested that the enzyme may be galactokinase. The optimum conditions for activity and a method for partial purification are described.
Cardini, Carlos E.   +1 more
openaire   +3 more sources

Galactosamine Hepatitis, Endotoxemia, and Lactulose [PDF]

open access: yesHepatology, 1983
Studies by Liehr et al. suggest that endotoxins are important in the pathogenesis of galactosamine hepatitis (Gal–N hepatitis) in rats. Lactulose (9.1 gm per kg per day) prevents hepatic lesions induced by Gal–N; an antiendotoxin effect of lactulose is postulated.
H, van Vugt, J, van Gool, L L, Thomas
openaire   +2 more sources

Targeted Sterically Stabilized Phospholipid siRNA Nanomedicine for Hepatic and Renal Fibrosis

open access: yesNanomaterials, 2016
Since its discovery, small interfering RNA (siRNA) has been considered a potent tool for modulating gene expression. It has the ability to specifically target proteins via selective degradation of messenger RNA (mRNA) not easily accessed by conventional ...
Fatima Khaja   +3 more
doaj   +1 more source

Possible Association Between DHEA and PKCε in Hepatic Encephalopathy Amelioration: A Pilot Study

open access: yesFrontiers in Veterinary Science, 2021
Objective: Hepatic encephalopathy (HE) is a neuropsychiatric syndrome caused by liver failure and by an impaired neurotransmission and neurological function caused by hyperammonemia (HA).
Alessandro Di Cerbo   +7 more
doaj   +1 more source

Fluorogenic Coupled Assays Reveal Catalytic Properties, Inhibition Constants and Cellular Location of Mucin‐Active Carbohydrate Sulfatases

open access: yesAngewandte Chemie, EarlyView.
We report plate‐based coupled assays to rapidly and quantitatively determine the activity and selectivity of mucin‐active carbohydrate sulfatases. This fluorogenic assay further enables inhibitor identification and allows determination of (sub‐)cellular location. ABSTRACT Sulfated glycans play a central role in human health and influence cell signaling,
Charles W. E. Tomlinson   +5 more
wiley   +2 more sources

Hepatoprotective activity of a new polyherbal formulation against paracetamol and D-galactosamine induced hepatic toxicity

open access: yesJournal of Pharmacy and Bioallied Sciences, 2015
Objective: The present study was envisaged to evaluate the protective effect of polyherbal formulation, DRDC/AY/8060, developed by Dabur India Ltd., against paracetamol and D-galactosamine induced hepatic toxicities in Wistar rats. Materials and Methods:
Mohammad Ahmed Khan   +4 more
doaj   +1 more source

HPLC-PDA-MS/MS Characterization of Bioactive Secondary Metabolites from Turraea fischeri Bark Extract and Its Antioxidant and Hepatoprotective Activities In Vivo

open access: yesMolecules, 2017
Turraea fischeri is an East African traditional herb, which is widely used in traditional medicine. In this study, we profiled the secondary metabolites in the methanol extract of T.
Mansour Sobeh   +6 more
doaj   +1 more source

Weiteres über Galactosamin. [PDF]

open access: yesHoppe-Seyler´s Zeitschrift für physiologische Chemie, 1901
n ...
Schulz, Fr. N., Ditthorn, Fr.
openaire   +2 more sources

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