Results 51 to 60 of about 5,015 (194)

Hyperglycaemia‐induced reactive oxygen species production in cardiac ventricular myocytes differs among mammals

The Journal of Physiology, EarlyView.
Abstract figure legend In rat and human adult ventricular myocytes, acute hyperglyceaemia (Glucose) causes increased glucose uptake (via GLUT) leading to O‐GlcNAcylation of CaMKII at Ser280, such that CaMKII activates NADPH oxidase 2 (NOX2) to increase cytosolic reactive oxygen species (ROS). That perturbs the ROS to Antioxidant (AntiOx) balance.
Shan Lu, Maria J. Baier, Risto‐Pekka Polonen, Zhandi Liao, Jody L. Martin, Kenneth S. Ginsburg, Julian Mustroph, Donald M. Bers   +7 more
wiley   +1 more source

Prediction of course and progression of nonalcoholic fatty liver disease in patients with obesity and pathology of the biliary tract with the help of mathematical modeling.

Medičnì Perspektivi, 2017
Determination of the most important functional parameters of the liver, lipid peroxidation (LPO) and antioxidant protection (AOP) markers of endogenous intoxication and indicators of connective-tissue metabolism in patients with non-alcoholic fatty liver
A. Yu. Filippova, I. A. Gubar, V. V. Rudakova   +2 more
doaj   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, Volume 101, Issue 2, Page 751-803, April 2026.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

A novel type of meso-diaminopimelic acid-based peptidoglycan and novel poly(erythritol phosphate) teichoic acids in cell walls of two coryneform isolates from the surface flora of French cooked cheeses [PDF]

, 1993
The primary structure of the peptidoglycan and the teichoic acids of two coryneform isolates from the surface flora of French cooked cheeses, CNRZ 925 and CNRZ 926, have been determined.
Accolas, Jean-Pierre, Fiedler, Franz, Reiml, Dieter, Schubert, Karin   +3 more
core  

Can neap-spring tidal cycles modulate biogeochemical fluxes in the abyssal near-seafloor water column? [PDF]

, 2017
Before particulate matter that settles as ‘primary flux’ from the interior ocean is deposited into deep-sea sediments it has to traverse the benthic boundary layer (BBL) that is likely to cover almost all parts of the seafloor in the deep seas.
Dale, Andrew, Lahajnar, Niko, Lampitt, Richard S,, Sakamoto, Kei, Turnewitsch, Robert   +4 more
core   +1 more source

Diabetic kidney disease, biomarkers, and finerenone

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2582-2593, April 2026.
Abstract Diabetic kidney disease (DKD), the leading cause of kidney failure worldwide, is associated with an increased risk of cardiovascular disease (CVD). A complex pathobiology involving hemodynamic, metabolic, and immune dysregulation promotes inflammatory and fibrotic pathways that contribute to kidney disease progression and CVD in individuals ...
Ashish Verma, Ashish Upadhyay
wiley   +1 more source

Features of cytological picture at multiforme exudative erythema in oral cavity [PDF]

, 2016
Було вивчено цитологічну картину вмісту ерозій у хворих з токсико-алергічною формою мультиформної еритеми в порожнині рота. Було виявлено, що склад клітинних елементів неспецифічний. Гематогенні і гістіогенні клітини в основному незруйновані.
Karpets, L.M., Lakhtin, Yurii Volodymyrovych, Moskalenko, Pavlo Oleksandrovych, Лахтин, Юрий Владимирович, Лахтін, Юрій Володимирович, Москаленко, Павел Александрович, Москаленко, Павло Олександрович   +6 more
core  

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, Volume 36, Issue 24, 23 March 2026.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Aggressive and protective factors of gastric juice in patients with pyloroduodenal stenosis of the ulcerative origin

Gastroenterologìa, 2019
Background. The purpose was to evaluate the aggressive and protective properties of gastric juice depending on the severity of pyloroduodenal stenosis in patients with severe peptic ulcer disease. Materials and methods.
V.M. Ratchik, S.O. Tarabarov, A.I. Rudenko, N.V. Prolom   +3 more
doaj   +1 more source

Hexosamines Provoke Membrane Cholesterol Accrual, Filamentous Actin Loss, and GLUT4 Dysregulation in Adipocytes through Transcriptional Activation of Specificity Protein 1 [PDF]

, 2012
poster abstractThe hexosamine biosynthesis pathway (HBP) serves as a sensor of excess nutrient bioavailability and has been implicated in the pathogenesis of type 2 diabetes.
Elmendorf, Jeffrey S., Penque, Brent A.
core