Results 51 to 60 of about 5,058 (210)
Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting
Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi +2 more
wiley +1 more source
Biochemical & histochemical changes relating to fibrosis following, infection with Mycobacterium tuberculosis in the guineapig [PDF]
Guineapigs infected with M. tuberculosis were studied for pammeters relating to fibrosis following infection. The infected animals were followed up to a period of 44 wk and the changes that occurred in the lung, liver and spleen were studied ...
Jayasankar, K, Ramanathan, V D
core
Fibrinogen-related proteins in ixodid ticks
Background Fibrinogen-related proteins with lectin activity are believed to be part of the tick innate immune system. Several fibrinogen-related proteins have been described and characterised mainly on the basis of their cDNA sequences while direct ...
Vancova Marie +4 more
doaj +1 more source
Central illustration: Pathophysiological mechanisms linking diabetes mellitus and cardiovascular disease. Chronic hyperglycaemia, insulin resistance, and low‐grade inflammation contribute to endothelial dysfunction, myocardial fibrosis, and cardiomyocyte apoptosis.
Lilian Anagnostopoulou +13 more
wiley +1 more source
This study employs an interpretable machine learning framework to predict diabetes‐cancer comorbidity, with the Random Forest and LightGBM models demonstrating exceptional performance. SHAP value analysis reveals that while advanced age and cardiometabolic dysfunctions serve as primary risk drivers, dietary antioxidants (particularly daidzein and ...
Ming Xu +8 more
wiley +1 more source
Background. The purpose was to evaluate the aggressive and protective properties of gastric juice depending on the severity of pyloroduodenal stenosis in patients with severe peptic ulcer disease. Materials and methods.
V.M. Ratchik +3 more
doaj +1 more source
Defining the tumor microenvironment of non‐small cell lung cancer
The tumor microenvironment (TME) in non‐small cell lung cancer is highly heterogeneous, both at a patient level and tumor microenvironment resolution. Defining the tumor microenvironment from patient‐responders and non‐responders will aid in the development of targeted therapeutics specific for each individual patient.
Kidane Siele Embaye +5 more
wiley +1 more source
A novel type of meso-diaminopimelic acid-based peptidoglycan and novel poly(erythritol phosphate) teichoic acids in cell walls of two coryneform isolates from the surface flora of French cooked cheeses [PDF]
The primary structure of the peptidoglycan and the teichoic acids of two coryneform isolates from the surface flora of French cooked cheeses, CNRZ 925 and CNRZ 926, have been determined.
Accolas, Jean-Pierre +3 more
core
Explanation of the use of ozonated stem cells of cord blood
Introduction. Experimental studies using stem cells of cord blood were conducted on mature guinea pigs with the model of pancreatic necrosis. The results are presented in the article "Changes in the blood physical state regulation of guinea pigs with the
A. В. Kebkalo
doaj +1 more source
Leveraging extracellular vesicle biology for novel tests and therapeutics for kidney fibrosis
Extracellular vesicles (EVs) are bilipid membrane‐encased nanoparticles that play critical roles as cell‐to‐cell messengers and waste management mechanisms. EVs cargos can be leveraged as biomarkers to develop minimally invasive tests for kidney fibrosis and guide personalised mechanism‐driven care.
Chin‐Ya Sophie Chiang +3 more
wiley +1 more source

