Results 1 to 10 of about 1,408 (77)

In silico Approach for Unveiling the Glycoside Hydrolase Activities in Faecalibacterium prausnitzii Through a Systematic and Integrative Large-Scale Analysis [PDF]

Frontiers in Microbiology, 2019
This work presents a novel in silico approach to the prediction and characterization of the glycolytic capacities of the beneficial intestinal bacterium Faecalibacterium prausnitzii. Available F.
Guillermo Blanco, Guillermo Blanco, Guillermo Blanco, Borja Sánchez, Florentino Fdez-Riverola, Florentino Fdez-Riverola, Florentino Fdez-Riverola, Abelardo Margolles, Anália Lourenço, Anália Lourenço, Anália Lourenço, Anália Lourenço   +11 more
doaj   +7 more sources

A conserved motif in the hexosyltransferases [PDF]

Molecular Microbiology, 1999
Henderson, Ian R., Nataro, James P.
openaire   +5 more sources

Structural analysis and functional evaluation of the disordered ß–hexosyltransferase region from Hamamotoa (Sporobolomyces) singularis

Frontiers in Bioengineering and Biotechnology, 2023
Hamamotoa (Sporobolomyces) singularis codes for an industrially important membrane bound ß-hexosyltransferase (BHT), (BglA, UniprotKB: Q564N5) that has applications in the production of natural fibers such as galacto-oligosaccharides (GOS) and natural sugars found in human milk.
Suzanne F. Dagher, Asmita Vaishnav, Christopher B. Stanley, Flora Meilleur, Flora Meilleur, Brian F. P. Edwards, José M. Bruno-Bárcena   +6 more
openaire   +3 more sources

Heterologous Expression of a Bioactive β-Hexosyltransferase, an Enzyme Producer of Prebiotics, from Sporobolomyces singularis [PDF]

Applied and Environmental Microbiology, 2013
ABSTRACTGalacto-oligosaccharides (GOS) are indigestible dietary fibers that are able to reach the lower gastrointestinal tract to be selectively fermented by health-promoting bacteria. In this report, we describe the heterologous expression of an optimized synthetically produced version of the β-hexosyltransferase gene (Bht) fromSporobolomyces ...
Suzanne F, Dagher, M Andrea, Azcarate-Peril, José M, Bruno-Bárcena   +2 more
openaire   +2 more sources

Biochemical and Biophysical Characterization of the Sialyl-/Hexosyltransferase Synthesizing the Meningococcal Serogroup W135 Heteropolysaccharide Capsule [PDF]

Journal of Biological Chemistry, 2013
Neisseria meningitidis (Nm) is a leading cause of bacterial meningitis and sepsis. Crucial virulence determinants of pathogenic Nm strains are the polysaccharide capsules that support invasion by hindering complement attack. In NmW-135 and NmY the capsules are built from the repeating units (→ 6)-α-D-Gal-(1 → 4)-α-Neu5Ac-(2 →)n and (→ 6)-α-D-Glc-(1 → 4)
Romanow, Angela, Haselhorst, Thomas, Stummeyer, Katharina, Claus, Heike, Bethe, Andrea, Muehlenhoff, Martina, Vogel, Ulrich, von Itzstein, Mark, Gerardy-Schahn, Rita   +8 more
openaire   +3 more sources

A novel N-terminal region of the membrane β-hexosyltransferase: its role in secretion of soluble protein by Pichia pastoris

Microbiology, 2016
The β-hexosyltransferase (BHT) from Sporobolomyces singularis is a membrane-bound enzyme that catalyses transgalactosylation reactions to synthesize galacto-oligosaccharides (GOSs). To increase the secretion of the active soluble version of this protein, we examined the uncharacterized novel N-terminal region (amino acids 1-110), which included two ...
Suzanne F, Dagher, José M, Bruno-Bárcena   +1 more
openaire   +2 more sources

Pathogenic DDOST Variant Is Associated with Humoral Immune Deficiency. [PDF]

J Clin Immunol, 2023
Sitek A, Ligezka A, Budhraja R, Morava E, Chiarella SE.   +4 more
europepmc   +1 more source

A homozygous nonsense variant in the oligosaccharyltransferase complex gene, RPN1, causes a congenital disorder of glycosylation. [PDF]

HGG Adv
Ng BG, Zhang W, Neil JE, Danish M, Marafi D, Kamal TM, Bastaki L, Al Saffar M, Yang E, He M, Walsh CA, Mochida GH, Freeze HH.   +12 more
europepmc   +1 more source

Innovative Immobilization of <i>Aspergillus aculeatus</i> OI4C2 Fructosyltransferase on MANAE-Agarose Cross-Linked with Genipin for Enhanced Production of Fructooligosaccharides. [PDF]

J Agric Food Chem
Inagaki TS, de Andrades D, Souza Alves Picciarelli G, Polizeli MLTM, Poleto de Oliveira D, Pereira de Carvalho Junior V, Helfenstein Rother PD, Fabricio MF, Ayub MAZ, Hertz PF, Kadowaki MK.   +10 more
europepmc   +1 more source

Expanded Clinical Spectrum of Autosomal-Dominant STT3A-CDG. [PDF]

Biomolecules
Al-Shahrani H, Szabó E, Staccone C, MacDonald G, Furuta Y, Schecter D, Edmondson AC, McRae A, Baker J, Morava E, Tinker RJ.   +10 more
europepmc   +1 more source