Extraction and Optimization of Fucoidan From Sargassum muticum Using Acidic Eutectic Solvents and Evaluation of Their Effects on Fibroblast Cell Lines. [PDF]
Fucoidan, a sulfated polysaccharide extracted from the cell wall of macroalgae such as S. muticum, exhibits promising biological properties. This study investigated a green extraction using deep eutectic solvents (DESs), with an emphasis on process optimization and bioactive evaluation of fucoidan.
Leite M +8 more
europepmc +2 more sources
Erucastrum virgatum subsp. virgatum (Brassicaceae) Endemic to Sicily (Italy): Biological Properties and Phenolic Content of Leaf Extracts. [PDF]
ABSTRACT The present work reports a comparative study between extracts obtained by different methods (ultrasonic bath‐assisted extraction, maceration, decoction, and Soxhlet extraction) from the leaves of Erucastrum virgatum subsp. virgatum collected in Sicily (Italy), using ethanol and water as “green” solvents.
Galletta B +8 more
europepmc +2 more sources
Early Markers of Cardiac and Skeletal Muscle Metabolic Derangement in the Apc(min/+) Male Mouse. [PDF]
ABSTRACT Background and Aims Cancer cachexia is a metabolic and wasting disease that occurs in up to 80% of cancer patients. Currently, there are no clear diagnostic criteria, its effects are irreversible, and it cannot be treated. Most patients progress undetected to late stages of cancer cachexia, stop responding to traditional treatment, and die ...
Parry TL +7 more
europepmc +2 more sources
Glycosaminoglycans as Polyelectrolytes: Charge, Interactions, and Applications. [PDF]
Glycosaminoglycans (GAGs) are linear, anionic biopolymers with their functions tightly linked to their charge. This review approaches GAGs from a polyelectrolyte perspective, shedding light on how the distribution of sulfate groups and, thus, negative charges, governs their interactions with other biomolecules.
Szekeres GP +7 more
europepmc +2 more sources
Improving in vitro Gastrointestinal Stability of Phlorotannins From Food Grade Fucus vesiculosus Extracts Using Cyclodextrins. [PDF]
ABSTRACT Phlorotannins have gained significant attention for their potential bioactive and functional properties. However, these compounds are highly sensitive to gastrointestinal digestion, which limits their bioavailability and consequently the in vivo efficacy.
Reis SF +5 more
europepmc +2 more sources
Subcritical Water Hydrolysis of Citrus Pectin, Pea Protein Concentrate, and Their Mixture for Oligosaccharide and Peptide Production [PDF]
Bioactive oligosaccharides and peptides have drawn great attention due to reported health benefits such as antidiabetic, anti-obesity, anticancer, anti-hypertensive, and antioxidant.
Vo, Hung Ha Phuoc
core +2 more sources
Engineering of Corynebacterium glutamicum for growth and production of L-ornithine, L-lysine, and lycopene from hexuronic acids [PDF]
Hadiati A, Krahn I, Lindner S, Wendisch VF. Engineering of Corynebacterium glutamicum for growth and production of L-ornithine, L-lysine, and lycopene from hexuronic acids. Bioresources and Bioprocessing.
Irene Krahn +7 more
core +2 more sources
Assignment of hexuronic acid stereochemistry in synthetic heparan sulfate tetrasaccharides with 2-O-sulfo uronic acids using electron detachment dissociation [PDF]
The present work focuses on the assignment of uronic acid stereochemistry in heparan sulfate (HS) oligomers. The structural elucidation of HS glycosaminoglycans is the subject of considerable importance due to the biological and biomedical significance ...
Medicinal Chemistry and Chemical Biology +6 more
core +1 more source
The effect of enzyme treatment on the in vitro fermentation of Lucerne incubated with equine faecal inocula [PDF]
A series of experiments was conducted to determine the effects of a fibrolytic enzyme preparation (enzyme 1; E1) on the in vitro fermentation of lucerne incubated with equine faecal inocula.
Moore-Colyer, Meriel J. S. +10 more
core +1 more source
Protein O-glycosylation in the Bacteroidota phylum. [PDF]
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Hoffmanns L, Svedberg D, Mateus A.
europepmc +2 more sources

