Results 111 to 120 of about 43,089 (386)

Changes of calcium cycling in HFrEF and HFpEF

Mechanobiology in Medicine, 2023
Dysfunctions of calcium cycling occur in heart failure with reduced and preserved ejection fraction (HFrEF and HFpEF). HFrEF and HFpEF showed Ca2+ leakage at diastole. The compensation of Na+/Ca2+ exchanger and the decrease of T-tubule density reduces cytoplasmic Ca2+ concentration in HFrEF and impairs systolic function.
Shou, Jian, Huo, Yunlong
openaire   +2 more sources

Heart failure with preserved ejection fraction. [PDF]

, 2012
Heart failure with preserved ejection fraction (HFpEF) has recently emerged as a major cause of cardiovascular morbidity and mortality. Contrary to initial beliefs, HFpEF is now known to be as common as heart failure with reduced ejection fraction (HFrEF)
ElGuindy, A, Yacoub, MH
core   +1 more source

Growth differentiation factor‐15 and N‐terminal pro‐BNP in acute heart failure with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 888-899, April 2025.
Abstract Aims Heart failure with preserved ejection fraction (HFpEF) continues to be an increasingly common health problem associated with a high mortality rate. Elevated levels of Growth differentiation factor‐15 (GDF15) and N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) are reportedly associated with poor clinical outcomes in a broad range of ...
Yoichiro Otaki, Tetsu Watanabe, Mari Shimizu, Shingo Tachibana, Junya Sato, Yuta Kobayashi, Harutoshi Tamura, Shigehiko Kato, Satoshi Nishiyama, Hiroki Takahashi, Takanori Arimoto, Masafumi Watanabe   +11 more
wiley   +1 more source

The role of cardiac acoustic biomarkers in monitoring patients with heart failure: A systematic literature review

ESC Heart Failure, Volume 12, Issue 2, Page 980-997, April 2025.
Abstract Heart failure (HF) creates a considerable clinical, humanistic and economic burden on patients and caregivers as well as on healthcare systems. To attenuate the significant burden of HF, there is a need for enhanced management of patients with HF.
Javed Butler, Malcolm Brown, Philippe Prokocimer, Ashley C. Humphries, Sophie Pope, Olivia Wright, Jun Su, Osama Elnawasany, Bogdan Muresan   +8 more
wiley   +1 more source

Clinical, Echocardiographic, and Therapeutic Characteristics of Heart Failure in Patients with Preserved, Mid-Range, and Reduced Ejection Fraction: Future Directions

International Journal of General Medicine, 2021
Manal M Alem Department of Pharmacology, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi ArabiaCorrespondence: Manal M AlemDepartment of Pharmacology, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal ...
Alem MM
doaj  

Microvascular and lymphatic dysfunction in HFpEF and its associated comorbidities

Basic Research in Cardiology, 2020
Heart failure with preserved ejection fraction (HFpEF) is a complex heterogeneous disease for which our pathophysiological understanding is still limited and specific prevention and treatment strategies are lacking.
I. Cuijpers, S. Simmonds, M. van Bilsen, E. Czarnowska, A. González Miqueo, S. Heymans, Annika R. Kuhn, P. Mulder, A. Ratajska, E. Jones, E. Brakenhielm   +10 more
semanticscholar   +1 more source

Dynamic changes and prognostic value of pulmonary congestion by lung ultrasound in acute and chronic heart failure: a systematic review [PDF]

, 2017
Aims: Pulmonary congestion is an important finding in patients with heart failure (HF) that can be quantified by lung ultrasound (LUS). We conducted a systematic review to describe dynamic changes in LUS findings of pulmonary congestion (B-lines) in ...
Al Deeb, Ambrosy, Butler, Cleland, Cogliati, Coiro, Cortellaro, Facchini, Frassi, Frasure, Gargani, Gheorghiade, Gustafsson, Hlatky, Joynt, Kim, Lala, Martindale, Melenovsky, O'Connor, Pfeffer, Picano, Pivetta, Platz, Platz, Stroup, Vitturi, Volpicelli, Volpicelli, Wang   +29 more
core   +1 more source

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Association Between Visceral Fat, Blood Pressure and Arterial Stiffness in Patients with HFpEF: A Mediation Analysis

Diabetes, Metabolic Syndrome and Obesity, 2023
Min Sun,1,2 Lei Gao,1 Hongmei Bai,1 Weiwei Hu,1 Xiaofang Zhang,1 Jin Xiao,1 Xiangliang Deng,1 Hongmei Tao,1 Ping Ge,2 Yuhong Qin,1,* Dongying Zhang1,* 1Department of Cardiovascular Medicine, The First Affiliated Hospital of Chongqing Medical ...
Sun M, Gao L, Bai H, Hu W, Zhang X, Xiao J, Deng X, Tao H, Ge P, Qin Y, Zhang D   +10 more
doaj  

Effect of Praliciguat on Peak Rate of Oxygen Consumption in Patients With Heart Failure With Preserved Ejection Fraction: The CAPACITY HFpEF Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2020
Importance Heart failure with preserved ejection fraction (HFpEF) is often characterized by nitric oxide deficiency. Objective To evaluate the efficacy and adverse effects of praliciguat, an oral soluble guanylate cyclase stimulator, in patients with ...
J. Udelson, G. Lewis, Sanjiv J. Shah, M. Zile, M. Redfield, J. Burnett, J. Parker, J. Seferovic, Phebe J. Wilson, R. Mittleman, A. Profy, M. Konstam   +11 more
semanticscholar   +1 more source