Results 131 to 140 of about 21,749 (235)

Heart-Lung Interactions in Pulmonary Hypertension due to Heart Failure With Preserved Ejection Fraction. [PDF]

Compr Physiol
Prabala P, Raza F, Chesler NC.
europepmc   +1 more source

Determinants of Abnormal Pulmonary Vasodilatory Response With Exercise in HFpEF: Pulmonary Vascular‐Left Atrial Axis Abnormalities

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Compared to traditional cardiometabolic comorbidities, COPD and atrial fibrillation are uniquely linked to pulmonary vascular remodeling in HFpEF. The impact of these two comorbidities on pulmonary vascular‐left atrial axis is highlighted by the shared biventricular morphology among HFpEF subgroups.
Mariana Garcia‐Arango, Angela Kristo, Ahmed El Shaer, Yimin Chen, Aditya Sahai, Anas Abed, Wanxin Tu, Soham Ghosh, Babak Tehrani, Shannon Heffernan, Amir Esmaeeli, Tashfeen Javaid, Ran Tao, Naga Dharmavaram, James Runo, Alejandro Roldán‐Alzate, Adam D. Gepner, Matthew Kalscheur, Colleen M. Witzenburg, Ryan J. Tedford, Farhan Raza   +20 more
wiley   +1 more source

Assessment of Pulmonary Vascular Impedance in Patients With Severe Pulmonary Arterial Hypertension

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Pulmonary vascular impedance (PVZ) was calculated from clinical PA pressure and RVOT flow velocity profiles. Participants with increased pulmonary vascular resistance have increased PVZ, afterload, and diastolic stiffness. The characteristic impedance (ZC) to mean PA pressure relationship models the effect of proximal vasculature remodeling on ZC for a
Keeley Shea Ravellette, Saad Kubba, Frank Servin, Michael Insel, Joe G. N. Garcia, Tushar Acharya, Franz P. Rischard, Rebecca R. Vanderpool   +7 more
wiley   +1 more source

Heart failure and preserved ejection fraction: pathophysiology, clinical assessment, and management of exercise intolerance. [PDF]

Eur Heart J
Landsteiner I, Verwerft J, Belov D, Verbrugge FH, Lewis GD.   +4 more
europepmc   +1 more source

Myocardial Lipid Metabolism Imbalance: The Pathological Core and Novel Diagnostic‐Therapeutic Directions of Cardiovascular Diseases

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
In cardiac cells, Plin5/AMPK regulate lipid homeostasis; excess CD36‐mediated uptake drives lipotoxicity, mitochondrial dysfunction, and CVDs (e.g., heart failure). Biomarkers (ApoB/ApoA‐1) and therapies (SGLT2 inhibitors) target this cascade. ABSTRACT Cardiac lipid metabolism is fundamental to myocardial energy homeostasis, with fatty acid oxidation ...
Peiyun Xie, Qun Zeng, Hongrui Wang, Meihua She   +3 more
wiley   +1 more source

Valvular Heart Disease in Heart Failure with Preserved Ejection Fraction. [PDF]

Card Fail Rev
Adeli A, Sampath-Kumar R, Wang A, Manouras A, Savarese G, Hahn RT, Lund LH, Shahim B.   +7 more
europepmc   +1 more source

Atrial High‐Rate Episodes Mirror Atrial Fibrillation in Stroke Prediction: Evidence From an Indian Prospective Cohort

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
This prospective matched cohort study, which generates hypotheses, finds that device‐detected AF lasting under 24 h is linked to a notably increased risk of stroke/TIA and progression to clinical AF among Indian patients. ABSTRACT Aims To assess the risk of stroke/TIA and progression to atrial fibrillation (AF) in Indian patients with device‐detected ...
Sedhupathi Shanmugam, Sreevilasam P. Abhilash, Jyothi Vijay, Sapna erat Sreedharan, Narayanan Namboodiri   +4 more
wiley   +1 more source

Aging and HFpEF: Are we running out of time?

Journal of Molecular and Cellular Cardiology, 2022
Withaar, Coenraad, Li, Sunhuo, Meems, Laura M.G., Silljé, Herman H.W., de Boer, Rudolf A.   +4 more
openaire   +3 more sources

Screening for HFpEF in pacemaker patients: Study design and protocol of the PM-HFpEF study. [PDF]

PLoS One
Santos E, Teixeira R, Almeida J, Fonseca P, Oliveira M, Gonçalves H, Primo J, Diaz S, Barros A, Vilela E, Sampaio F, Saraiva F, Oliveira M, de Carvalho RF.   +13 more
europepmc   +1 more source

Utility of Post‐Procedural HFA‐PEFF Reassessment for Long‐Term Heart Failure Risk Stratification After Atrial Fibrillation Ablation

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
In this single‐center cohort of 856 patients with preserved left ventricular ejection fraction undergoing atrial fibrillation ablation, post‐procedural HFA‐PEFF reassessment provided better long‐term discrimination for heart failure hospitalization than pre‐procedural assessment over a median 5.2‐year follow‐up.
Hironori Ishiguchi, Yasuhiro Yoshiga, Masakazu Fukuda, Shintaro Hashimoto, Goki Nakashima, Takuya Omuro, Akihiko Shimizu, Motoaki Sano   +7 more
wiley   +1 more source