Results 151 to 160 of about 30,754 (261)

Slow calcium removal contributes to impaired lusitropic response to β‐adrenergic stimulation in HFpEF mice

The Journal of Physiology, EarlyView.
Abstract figure legend Heart failure with preserved ejection fraction (HFpEF) is the most common form of heart failure, yet major gaps remain in our understanding of its underlying mechanisms, disease progression and effective treatment strategies. Mice with HFpEF exhibited exercise intolerance and diastolic dysfunction in vivo, while isolated hearts ...
Tamzin Zawadzki, Diana S. Usai, Sif G. Kaad, Katrine H. Rasmussen, Mie S. Larsen, Jens C. B. Jacobsen, Morten B. Thomsen   +6 more
wiley   +1 more source

The role of ventricular-arterial coupling indicators in patients with acute heart failure with preserved ejection fraction

reservedRazionale e scopo. Lo scompenso cardiaco a frazione di eiezione preservata (HFpEF) è la forma più frequente di scompenso cardiaco nei pazienti ricoverati in Medicina Interna, con una prevalenza in aumento negli ultimi anni. La diagnosi di HFpEF
GRIMOLDI, FEDERICO
core  

Development of a heart failure with preserved ejection fraction risk prediction score in primary care settings with a high HIV prevalence. [PDF]

Open Heart
Honwana F, Wolfson J, Ahmed AM, Huang Z, Mgidlana M, Aremu O, Omar Z, Ntusi N, Meintjes G, Myer L, Baker JV, Ntsekhe M.   +11 more
europepmc   +1 more source

SGLT2i in heart failure: Cardiorenal mechanisms, clinical evidence and translational perspectives

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
SGLT2 inhibitors improve heart failure outcomes through integrated cardiorenal mechanisms. In the kidney, they reduce glucose and sodium reabsorption, promoting natriuresis, osmotic diuresis and renal protection. In the heart, they enhance myocardial energetics, reduce inflammation, oxidative stress, fibrosis and adverse remodelling, resulting in fewer
Jelica Grujic‐Milanovic, Jovana Rajkovic, Radmila Novakovic, Javad Sharifi‐Rad, Daniela Calina   +4 more
wiley   +1 more source

Coronary microvascular dysfunction in HFpEF: pathophysiologic mechanisms, diagnosis, treatments, and the amplifying potential of sepsis. [PDF]

Front Med (Lausanne)
Chattha S, Kapadia K, Lynch D, McWhorter Y.   +3 more
europepmc   +1 more source

Molecular Pathways, Target Landscape, and Translational Models in Heart Failure with Preserved Ejection Fraction. [PDF]

Cells
Qamar H, Saini JS, Figarska SM, Buys ES, Wagh V.   +4 more
europepmc   +1 more source

Neutrophil Extracellular Traps in Atherosclerosis and Cardiovascular Disease

MedComm, Volume 7, Issue 10, October 2026.
NETs as integrated effectors in the atherosclerotic cardiovascular disease continuum. Activated neutrophils release NETs that promote endothelial injury, thrombo‐inflammation, and plaque destabilization throughout atherosclerotic disease progression. Created with BioRender.com.
Ji Zhang, Fangjiaqi Wei, Mengdi Qu, Yuwen Shao, Tingye Xu, Darko Stojkov, Hans‐Uwe Simon, Ben Huang, Changhong Miao, Hao Zhang   +9 more
wiley   +1 more source

Heart failure with a preserved ejection fraction: synergy between cardiac and extracardiac mechanisms and effects of novel therapies. [PDF]

Heart Fail Rev
Nassiri S, Handoko ML, van de Bovenkamp AA, van Empel VPM, van Raalte DH, Eringa EC.   +5 more
europepmc   +1 more source

Osteopontin in HFpEF

Journal of the American College of Cardiology, 2019
Fadi N. Salloum, Vinh Q. Chau
openaire   +1 more source

Cardiovascular–Kidney–Metabolic Overlaps, Clinical Outcomes, and Medications Among Patients With Heart Failure: Results From the Chinese Cardiovascular Association Database–Heart Failure Center Registry

MedComm, Volume 7, Issue 10, October 2026.
In a nationwide heart failure cohort, cardiovascular–kidney–metabolic (CKM) multimorbidity was common in Chinese hospitalized heart failure (HF) patients and associated with poor prognosis. Higher CKM burden and combinations identified high‐risk patients.
Xiang Wang, Jingkuo Li, Yi Li, Lubi Lei, Wei Wang, Xuyang Meng, Chenxi Xia, Chenguang Yang, Lihua Zhang, Yuhua Liao, Weimin Li, Yugang Dong, Xinli Li, Jingmin Zhou, Jiefu Yang, Fang Wang   +15 more
wiley   +1 more source