Results 161 to 170 of about 30,754 (261)

High-probability heart failure with preserved ejection fraction phenotype in atrial fibrillation patients undergoing ablation: insights from RECAP. [PDF]

Europace
Erzeel J, De Wever M, van Es M, Dhont S, Mullens W, Pison L, Martens P.   +6 more
europepmc   +1 more source

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

Brain perivascular diffusion and cognitive impairment in heart failure with preserved ejection fraction. [PDF]

Front Med (Lausanne)
Yu T, Duan C, Sun M, Liu Y, Yuan Y.
europepmc   +1 more source

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

British Journal of Pharmacology, Volume 183, Issue 19, Page 5732-5751, October 2026.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam, James Harris, Jürgen Bernhagen, Antony Vinh, Katrina M. Mirabito Colafella   +4 more
wiley   +1 more source

Within a Heartbeat: A Machine Learning Approach Using VCG for Heart Failure Assessment in Sinus Rhythm. [PDF]

J Pers Med
Karagiannis IM, Samaras A, Filos D, Giannakoulas G, Chouvarda I.   +4 more
europepmc   +1 more source

Cardiovascular Autonomic Neuropathy and Indices of Heart Failure in Type 2 Diabetes: The CANCAN Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9356-9366, October 2026.
ABSTRACT Aim To quantify the association between cardiovascular autonomic neuropathy (CAN) and heart failure (HF) in individuals with type 2 diabetes (T2D). Materials and Methods Two hundred T2D individuals were recruited from two Danish outpatient clinics between 2021–2024. CAN was defined by abnormal cardiovascular autonomic reflex test results.
Jonas R. Schaarup, Lasse Bjerg, Christian S. Hansen, Daniel R. Witte, Henrik H. Thomsen, Jesper Fleischer, Rodica Pop‐Busui, Signe T. Andersen   +7 more
wiley   +1 more source

HFpEF-ABA Score for the Diagnosis and Prognosis of HFpEF in Outpatients With Type 2 Diabetes. [PDF]

JACC Adv
Gonzalez-Manzanares R, Anguita M, Muñiz J, Barrios V, Gimeno-Orna JA, Pérez A, Rodríguez-Padial L, Anguita-Gámez M.   +7 more
europepmc   +1 more source

Glycemic and Renal Effects of SGLT2 Inhibitors in Monogenic Diabetes: A Real‐World National Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9633-9643, October 2026.
ABSTRACT Aims Evidence regarding the efficacy and safety of sodium–glucose cotransporter 2 inhibitors (SGLT2i) in monogenic diabetes is limited. We evaluated real‐world metabolic, renal, and safety outcomes of SGLT2i therapy in adults with monogenic diabetes.
Estelle Audrain, Pierre Bel Lassen, Christine Bellanné‐Chantelot, Marie Christine Vantyghem, Hippolyte Dupuis, Tiphaine Vidal‐Trecan, Nicolas Chevalier, Danièle Dubois‐Laforgue, Sophie Lamothe, Camille Vatier, Orianne Villard, René Valéro, Claire Briet, Corinne Vigouroux, Cécile Ciangura, Chloé Amouyal   +15 more
wiley   +1 more source

Heart failure with preserved ejection fraction in women: a sex-specific clinical review. [PDF]

Korean J Intern Med
Kim SJ, Shin MS.
europepmc   +1 more source

Valvular Heart Disease as the Main Cause of Acute Heart Failure with Preserved Ejection Fraction: Dynamic Severe Functional Valvular Regurgitation as the Main Mechanism of Decompensation. [PDF]

Card Fail Rev
Bellicini MG.
europepmc   +1 more source