New pharmacological treatments for heart failure with reduced ejection fraction (HFrEF)
Background: Heart failure with reduced ejection fraction (HFrEF) has contributed to an increasing number of deaths and readmissions over the past few decades.
Heng Li+7 more
semanticscholar +1 more source
Effect on Mortality of Higher Versus Lower β-Blocker (Metoprolol Succinate or Carvedilol) Dose in Patients With Heart Failure [PDF]
This study aimed to compare the effect of β-blocker dose and heart rate (HR) on mortality in patients with heart failure with reduced ejection fraction (HFrEF).
Ajam, Samer+4 more
core +1 more source
cBIN1 Score (CS) Identifies Ambulatory HFrEF Patients and Predicts Cardiovascular Events
Background Cardiac Bridging Integrator 1 (cBIN1) is a membrane deformation protein that generates calcium microdomains at cardiomyocyte t-tubules, whose transcription is reduced in heart failure, and is released into blood.
T. Hitzeman+21 more
semanticscholar +1 more source
Identifying Pathophysiological Mechanisms in Heart Failure With Reduced Versus Preserved Ejection Fraction [PDF]
Background: Information on the pathophysiological differences between heart failure with reduced ejection fraction (HFrEF) versus heart failure with preserved ejection fraction (HFpEF) is needed Objectives: The purpose of this study was to establish ...
Anker, Stefan D.+18 more
core +3 more sources
Different determinants of exercise capacity in HFpEF compared to HFrEF
Quality of life is as important as survival in heart failure (HF) patients. Controversies exist with regards to echocardiographic determinants of exercise capacity in HF, particularly in patients with preserved ejection fraction (HFpEF). The aim of this study was to prospectively examine echocardiographic parameters that correlate and predict ...
Shpend Elezi+8 more
openaire +5 more sources
The Multi-Biomarker Approach for Heart Failure in Patients with Hypertension [PDF]
We assessed the predictive ability of selected biomarkers using N-terminal pro-brain natriuretic peptide (NT-proBNP) as the benchmark and tried to establish a multi-biomarker approach to heart failure (HF) in hypertensive patients. In 120 hypertensive
Agata Bielecka-Dabrowa+10 more
core +2 more sources
New in the diagnosis of heart failure and management of associated conditions in 2021 ESC guidelines
Oben Baysan+2 more
doaj +1 more source
Frailty, Guideline-Directed Medical Therapy, and Outcomes in HFrEF: From the GUIDE-IT Trial.
M. S. Khan+10 more
semanticscholar +1 more source
Isosorbide dinitrate, with or without hydralazine, does not reduce wave reflections, left ventricular hypertrophy, or myocardial fibrosis in patients with heart failure with preserved ejection fraction [PDF]
Background-Wave reflections, which are increased in patients with heart failure with preserved ejection fraction, impair diastolic function and promote pathologic myocardial remodeling.
Akers, Scott+13 more
core +1 more source