Results 71 to 80 of about 37,898 (281)

What can we learn from SOCRATES: more questions than answers? [PDF]

, 2017
This editorial refers to ‘Vericiguat in patients with worsening chronic heart failure and preserved ejection fraction: results of the SOluble guanylate Cyclase stimulatoR in heArT failurE patientS with PRESERVED EF (SOCRATES-PRESERVED) Study’, by B ...
Cleland, John G.F., Mueller, Christian
core   +1 more source

Comparison of procedural outcomes in patients undergoing catheter vs surgical ablation for atrial fibrillation and heart failure with reduced ejection fraction

Journal of Arrhythmia, 2021
Background There is a lack of research comparing procedural outcomes of surgical ablation (SA) and catheter ablation (CA) among patients with heart failure with reduced ejection fraction (HFrEF) and atrial fibrillation (AF).
Rajkumar Doshi, Ashish Kumar, Mariam Shariff, Devina Adalja, Krunalkumar Patel, Kirtenkumar Patel, Rupak Desai, Nageshwara Gullapalli, Saraschandra Vallabhajosyula   +8 more
doaj   +1 more source

The impact of peripheral arterial disease on patients with mechanical circulatory support. [PDF]

, 2020
Background: Left ventricular assist devices (LVAD) are indicated as bridging or destination therapy for patients with advanced (Stage D) heart failure and reduced ejection fraction (HFrEF). Due to the clustering of the mutual risk factors, HFrEF patients
Ajmal, Rasikh, Al-Khadra, Yasser, Alraies, M Chadi, Asfour, Abedelrahim, Darmoch, Fahed, Gardi, Delair, Glazier, James, Mir, Tanveer, Moussa-Pacha, Homam, Sattar, Yasar, Ullah, Waqas   +10 more
core   +1 more source

Integration of RNA-Seq and Machine Learning Identifies Hub Genes for Empagliflozin Benefitable Heart Failure with Reduced Ejection Fraction

Journal of Inflammation Research, 2023
Qiang Yang,1,* Jing Gao,2,* Tian-Yu Wang,1 Jun-Can Ding,1 Peng-Fei Hu3 1Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang Province, 310053, People’s Republic of China; 2Department of Cardiology, Sir Run Run ...
Yang Q, Gao J, Wang TY, Ding JC, Hu PF
doaj  

Profibrotic, Electrical, and Calcium-Handling Remodeling of the Atria in Heart Failure Patients With and Without Atrial Fibrillation

Frontiers in Physiology, 2018
Atrial fibrillation (AF) and heart failure (HF) are common cardiovascular diseases that often co-exist. Animal models have suggested complex AF-promoting atrial structural, electrical, and Ca2+-handling remodeling in the setting of HF, but data in human ...
Cristina E. Molina, Cristina E. Molina, Cristina E. Molina, Issam H. Abu-Taha, Qiongling Wang, Elena Roselló-Díez, Marcus Kamler, Stanley Nattel, Stanley Nattel, Stanley Nattel, Ursula Ravens, Ursula Ravens, Xander H. T. Wehrens, Leif Hove-Madsen, Jordi Heijman, Dobromir Dobrev   +15 more
doaj   +1 more source

Impact of Renal Impairment on Beta-Blocker Efficacy in Patients With Heart Failure. [PDF]

, 2019
BACKGROUND: Moderate and moderately severe renal impairment are common in patients with heart failure and reduced ejection fraction, but whether beta-blockers are effective is unclear, leading to underuse of life-saving therapy.
Andersson, B, Anker, SD, Beta-Blockers in Heart Failure Collaborative Group, Böhm, M, Cleland, JGF, Coats, AJS, Damman, K, Flather, MD, Gill, SK, Holmes, J, Kjekshus, J, Kotecha, D, Manzano, L, McMurray, JJV, Packer, M, Redon, J, Rigby, AS, Rosano, G, Ruschitzka, F, van Veldhuisen, DJ, von Lueder, TG, Wedel, H, Wikstrand, J   +22 more
core   +8 more sources

Risk factors for new-onset heart failure with reduced or preserved ejection fraction in patients with ischemic heart disease: A cohort study

Journal of Clinical Sciences, 2021
Background: Risk factors for heart failure (HF) with reduced ejection fraction (HFrEF) or HF with preserved ejection fraction (HFpEF) in Ethiopian and Sub-Saharan African patients with ischemic heart disease (IHD) is not well-known.
Senbeta Guteta Abdissa
doaj   +1 more source

LncRNA Foxo6os as a Novel “ Scaffold” Mediates MYBPC3 in Combating Pathological Cardiac Hypertrophy and Heart Failure

Advanced Science, EarlyView.
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng, Qin Lin, Yizhuo Sun, Yilei Meng, Sangyu Hu, Huaming Cao, Fang Lin, Yuping Zhu, Luying Peng, Li Li   +9 more
wiley   +1 more source

Clinical, Echocardiographic, and Therapeutic Characteristics of Heart Failure in Patients with Preserved, Mid-Range, and Reduced Ejection Fraction: Future Directions

International Journal of General Medicine, 2021
Manal M Alem Department of Pharmacology, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi ArabiaCorrespondence: Manal M AlemDepartment of Pharmacology, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal ...
Alem MM
doaj  

Glucose-Induced Hemodynamic and Metabolic Response of Skeletal Muscle in Heart Failure Patients with Reduced vs. Preserved Ejection Fraction—A Pilot Study

Journal of Cardiovascular Development and Disease, 2022
(1) Background: Insulin resistance (IR) is a characteristic pathophysiologic feature in heart failure (HF). We tested the hypothesis that skeletal muscle metabolism is differently impaired in patients with reduced (HFrEF) vs.
Michael Boschmann, Lars Klug, Frank Edelmann, Anja Sandek, Stephan von Haehling, Hans-Dirk Düngen, Jochen Springer, Stefan D. Anker, Wolfram Doehner, Nadja Jauert   +9 more
doaj   +1 more source