Results 81 to 90 of about 19,142 (214)

Guidance or Misdirection? Unpacking the Role of Feedback in Health Preference Assessments

Health Economics, EarlyView.
ABSTRACT This study investigated the impact of providing feedback to respondents on a dominance‐structured choice task on subsequent choice behavior in a discrete choice experiment (DCE). The DCE was conducted among 626 patients with heart failure. Respondents were given a dominance‐structured choice task in which two devices (Device A and Device B ...
Mesfin G. Genie, Shelby D. Reed, Semra Ozdemir   +2 more
wiley   +1 more source

Comparative analysis of serum galanin levels in patients with coronary artery disease with and without heart failure with reduced ejection fraction and in individuals without cardiovascular diseases

Кардиоваскулярная терапия и профилактика
Aim. To study the level of the neuro-regulatory peptide galanin in pa­tients with coronary artery disease (CAD) with and without heart failu­re with reduced ejection fraction (HFrEF) in comparison with individuals without cardiovascular disease (CVD ...
Yu. S. Timofeev, A. A. Yafarova, A. F. Sheptulina, A. R. Kiselev, V. A. Metelskaya, N. I. Dubovskaya, O. M. Drapkina   +6 more
doaj   +1 more source

Sacubitril/Valsartan Ameliorates Inflammation and Oxidative Stress in Hypertensive Heart Disease by Upregulating CAMKK2 Protein and Modulating the AMPK/AKT/GSK‐3β Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Sacubitril/valsartan (Sac/Val) has emerged as an effective compound with myocardium‐protective functions in experimental and clinical trials for heart failure. This study investigated the function of Sac/Val in hypertensive heart disease (HHD) and explored the underlying mechanism.
Yan‐Jun Yang, Jiu‐Sheng Li
wiley   +1 more source

Cardiac surveillance in immune checkpoint inhibitor therapy: Insights from the Essen Cardio‐oncology Registry

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune checkpoint inhibitors (ICI) have revolutionized cancer therapy, offering improvements in survival across various malignancies. However, their toxicities pose a major challenge for cardio‐oncology units. Despite their growing importance, data on effectiveness of such specialized units in mitigating ICI‐associated ...
Elias Haj‐Yehia, Lisa Zimmer, Lena Lampe, Dimitra Vlachopoulou, Matthias Totzeck, Tienush Rassaf, Raluca I. Mincu   +6 more
wiley   +1 more source

Decreased endogenous nitric oxide production in acute decompensated heart failure with a reduced ejection fraction

ESC Heart Failure
Aims Heart failure represents a substantial burden to both patients and healthcare systems worldwide. Nitric oxide (NO) dysregulation may play a key role in patients transitioning from chronic to acute heart failure with a reduced ejection fraction ...
Roman Falls, Bing H. Wang, Sara Vogrin, Christopher J. Neil   +3 more
doaj   +1 more source

Cardiovascular Health in Women—Across the Lifespan

Clinical Endocrinology, EarlyView.
ABSTRACT Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity among women worldwide. However, CVD continues to be perceived as a predominantly male issue. CVD in women therefore remains understudied, underrecognized and undertreated.
Jaya Chandrasekhar, Jessica Yao, Simone Gong, Madhuka Wijayarathne, Monique Watts, Swati Mukherjee   +5 more
wiley   +1 more source

Comparing outcomes after pulmonary vein isolation in patients with systolic and diastolic heart failure

Heart Rhythm O2
Background: The benefit of pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF) and heart failure with reduced ejection fraction (HFrEF) is well established; its efficacy in patients with heart failure preserved ejection fraction ...
Ahmad B. Allaw, MD, Jeremy Treger, MD, PhD, Jia Guo, MD, Dipayon Roy, MD, Amulya Gampa, MD, Swati Rao, MD, Stephanie A. Besser, MSAS, Andrew D. Beaser, MD, Zaid Aziz, MD, Cevher Ozcan, MD, Srinath Yeshwant, MD, Gaurav A. Upadhyay, MD   +11 more
doaj   +1 more source

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

Cell Proliferation, EarlyView.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang, Ying Zhang, Yue Xu, Mengyuan Yang, Yuan Wei, Yuan Li, Tongyue Yang, Xu Wang, Chaona Yang, Qi Feng, Guolan Xing   +10 more
wiley   +1 more source

Mineralocorticoid receptor antagonists: Efficacy and safety in chronic kidney disease

Diabetes, Obesity and Metabolism, EarlyView.
Abstract The mineralocorticoid receptor (MR) has a multifaceted role in normal physiologic functions. However, research has uncovered the deleterious consequences of overactivation of the MR. It has been implicated in chronic kidney disease (CKD) via its strong association with glomerulosclerosis, interstitial fibrosis, proteinuria, and decline in ...
Amy K. Mottl, Kamlesh Khunti, Chantal Mathieu   +2 more
wiley   +1 more source

Iron deficiency in heart failure: Epidemiology, diagnostic criteria and treatment modalities

ESC Heart Failure, Volume 12, Issue 2, Page 723-726, April 2025.
Stephan von Haehling
wiley   +1 more source