Results 21 to 30 of about 13,891 (260)

DNA vaccines for HFRS: Laboratory and clinical studies

Virus Research, 2014
DNA vaccines can be constructed to produce specific immunogens while avoiding the risks associated with propagating infectious viruses. Plasmid DNA vaccines have well established manufacturing procedures and are safe in that they are replication defective, cannot revert to virulence and cannot be transmitted from person-to-person or into the ...
Connie S, Schmaljohn, Kristin W, Spik, Jay W, Hooper   +2 more
openaire   +3 more sources

Spatiotemporal variations and potential influencing factors of hemorrhagic fever with renal syndrome: A case study in Weihe Basin, China.

PLoS Neglected Tropical Diseases, 2023
BackgroundHemorrhagic fever with renal syndrome (HFRS) is a widespread zoonotic disease seriously threatening Chinese residents' health. HFRS of Weihe Basin remains highly prevalent in recent years and attracts wide attention.
Lingli Zhu, Liang Lu, Shujuan Li, Hongyan Ren   +3 more
doaj   +2 more sources

Epidemiological Characteristics of Hemorrhagic Fever with Renal Syndrome and Its Relationship with Meteorological Factors in Guangdong from 2015 to 2021 [PDF]

Zhongguo quanke yixue, 2022
Background Hemorrhagic fever with renal syndrome (HFRS) is a severe acute infectious disease and there are still some control deficiencies according to the epidemic report.
Jing TAN, Xiaoling HUANG, Ping HUANG, Lijun LIANG
doaj   +1 more source

The role of glomerular lesions in the prognosis of patients with acute kidney injury during hemorrhagic fever with renal syndrome

Renal Failure, 2023
Objective This study aimed to explore the role of glomerular lesions in patients who suffered from acute kidney injury (AKI) during hemorrhagic fever with renal syndrome (HFRS).Methods The study comprised 66 patients with AKI during HFRS treated at the ...
Min Min, Meiling Liu, Chunyu Lu, Lina Zhu, Jiong Zhang, Jinquan Wang   +5 more
doaj   +1 more source

Discovering common pathogenic processes between COVID-19 and HFRS by integrating RNA-seq differential expression analysis with machine learning

Frontiers in Microbiology, 2023
Zoonotic virus spillover in human hosts including outbreaks of Hantavirus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) imposes a serious impact on the quality of life of patients.
F. Noor, U. Ashfaq, Abu Bakar, Waqar ul Haq, Khaled S. Allemailem, Basmah F. Alharbi, W. Al-Megrin, Muhammad Tahir ul Qamar   +7 more
semanticscholar   +1 more source

The epidemic characteristics and changing trend of hemorrhagic fever with renal syndrome in Hubei Province, China. [PDF]

PLoS ONE, 2014
BACKGROUND: Hemorrhagic fever with renal syndrome (HFRS) is caused by different hantaviruses within the Bunyaviridae family. HFRS is a fulminant, infectious disease that occurs worldwide and is endemic in all 31 provinces of China.
Yi-Hui Zhang, Liang Ge, Li Liu, Xi-Xiang Huo, Hai-Rong Xiong, Yuan-Yuan Liu, Dong-Ying Liu, Fan Luo, Jin-Lin Li, Jia-Xin Ling, Wen Chen, Jing Liu, Wei Hou, Yun Zhang, Hong Fan, Zhan-Qiu Yang   +15 more
doaj   +1 more source

The Spatiotemporal Pattern and Its Determinants of Hemorrhagic Fever With Renal Syndrome in Northeastern China: Spatiotemporal Analysis

JMIR Public Health and Surveillance, 2023
BackgroundHemorrhagic fever with renal syndrome (HFRS) is a significant zoonotic disease mainly transmitted by rodents.
Yanding Wang, Xianyu Wei, Ruizhong Jia, XingYu Peng, Xiushan Zhang, Meitao Yang, Zhiqiang Li, Jinpeng Guo, Yong Chen, Wenwu Yin, Wenyi Zhang, Yong Wang   +11 more
doaj   +1 more source

HTNV infection of CD8+ T cells is associated with disease progression in HFRS patients

Communications Biology, 2021
Hantaan viruses (HTNVs) are zoonotic pathogens transmitted mainly by rodents and capable of infecting humans. Increasing knowledge of the human response to HTNV infection can guide the development of new preventative vaccines and therapeutic strategies ...
Rongrong Liu, Ruixue Ma, Zi-yu Liu, Haifeng Hu, Jiayi Shu, P. Hu, Junjun Kang, Yusi Zhang, Mingwei Han, Xiaoxiao Zhang, Yiting Zheng, Qikang Ying, Shi-Fang Hou, Wenqiu Wang, Fang Wang, Ning Cheng, Zhuang Yan, J. Lian, Xia Jin, Xingan Wu   +19 more
semanticscholar   +1 more source

Spatiotemporal association of rapid urbanization and water-body distribution on hemorrhagic fever with renal syndrome: A case study in the city of Xi'an, China.

PLoS Neglected Tropical Diseases, 2022
Hemorrhagic fever with renal syndrome (HFRS) is a zoonosis characterized by clinical features of high fever, hemorrhage, and renal damage. China has the largest number of HFRS cases worldwide, accounting for over 90% of the total reported cases.
Li Shen, Minghao Sun, Xiao Wei, Yao Bai, Qingwu Hu, Shuxuan Song, Boxuan Gao, Weilu Zhang, Jifeng Liu, Zhongjun Shao, Kun Liu   +10 more
doaj   +1 more source

Effects of Climate and Rodent Factors on Hemorrhagic Fever with Renal Syndrome in Chongqing, China, 1997-2008. [PDF]

PLoS ONE, 2015
China has the highest global incidence of hemorrhagic fever with renal syndrome (HFRS), constituting 90% of the cases in the world. Chongqing, located in the Three Gorges Reservoir Region, has been experiencing differences in the occurrence of HFRS from ...
Yuntao Bai, Zhiguang Xu, Bo Lu, Qinghua Sun, Wenge Tang, Xiaobo Liu, Weizhong Yang, Xinyi Xu, Qiyong Liu   +8 more
doaj   +1 more source