Results 111 to 120 of about 13,128 (181)

Fetal cardiac rhabdomyomas susceptible to prenatal treatment with mTOR inhibitors: literature review and proposal of a prenatal management algorithm

Frontiers in Medicine
Certain types of fetal cardiac rhabdomyomas can lead to severe complications, including intrauterine death, yet no specific criteria have been established for the prenatal use of pharmacological therapies to mitigate the impact of rhabdomyomas.
Alfonso Martinez-Garcia, Alfonso Martinez-Garcia, Omar A. Tirado-Aguilar, Sandra Acevedo-Gallegos, Juan M. Gallardo-Gaona, Berenice Velazquez-Torres, Jose A. Ramirez-Calvo, Dulce M. A. Camarena-Cabrera, Maria J. Rodriguez-Sibaja, Mario I. Lumbreras-Marquez, Mario I. Lumbreras-Marquez, Mario I. Lumbreras-Marquez, Yazmin Copado-Mendoza, Yazmin Copado-Mendoza   +13 more
doaj   +1 more source

Retracted: MiR‐191‐5p inhibits lung adenocarcinoma by repressing SATB1 to inhibit Wnt pathway

Molecular Genetics & Genomic Medicine, 2020
Background To investigate the function of miR‐191‐5p in lung adenocarcinoma and its possible mechanism. Methods QRT‐PCR was adopted for the detection of the expression levels of miR‐191‐5p and SATB1 (HGNC: 10541).
Lai‐yong Zhou, Fu‐wei Zhang, Jian Tong, Fang Liu   +3 more
doaj   +1 more source

DNF Sampling for ProbLog Inference [PDF]

, 2010
Inference in probabilistic logic languages such as ProbLog, an extension of Prolog with probabilistic facts, is often based on a reduction to a propositional formula in DNF. Calculating the probability of such a formula involves the disjoint-sum-problem,
Janssens, Gerda, Kimmig, Angelika, Mantadelis, Theofrastos, Shterionov, Dimitar Sht.   +3 more
core  

A Study of Thymidylate Synthase Expression as a Biomarker for Resectable Colon Cancer: Alliance (Cancer and Leukemia Group B) 9581 and 89803. [PDF]

, 2017
PurposeTumor levels of thymidylate synthase (TS), a target of 5-fluorouracil (5-FU)-based chemotherapy for colorectal cancer, have been studied as a predictive or prognostic biomarker with mixed results.Patients and methodsTumor TS levels were ...
Bertagnolli, Monica M, Colacchio, Thomas A, Compton, Carolyn C, Fuchs, Charles S, Goldberg, Richard M, Hasson, Rian M, Lenz, Heinz-Josef, Mayer, Robert J, Niedzwiecki, Donna, Ogino, Shuji, Redston, Mark, Saltz, Leonard B, Warren, Robert S, Ye, Cynthia   +13 more
core   +1 more source

Krüppel-like factors in cancer progression: three fingers on the steering wheel [PDF]

, 2013
Kruppel-like factors (KLFs) comprise a highly conserved family of zinc finger transcription factors, that are involved in a plethora of cellular processes, ranging from proliferation and apoptosis to differentiation, migration and pluripotency.
de Beeck, Ken Op, De Wever, Olivier, Lardon, Filip, LIMAME, RIDHA, Pauwels, Patrick   +4 more
core   +3 more sources

Natural Language Query in the Biochemistry and Molecular Biology Domains Based on Cognition Search™ [PDF]

Motivation: With the tremendous growth in scientific literature, it is necessary to improve upon the standard pattern matching style of the available search engines. Semantic NLP may be the solution to this problem.
Elizabeth J. Goldsmith, Saurabh Mendiratta, Radha Akella, Kathleen Dahlgren   +3 more
core   +1 more source

Proteome Based Construction of the Lymphocyte Function-Associated Antigen 1 (LFA-1) Interactome in Human Dendritic Cells. [PDF]

, 2016
The β2-integrin lymphocyte function-associated antigen 1 (LFA-1) plays an important role in the migration, adhesion and intercellular communication of dendritic cells (DCs).
A Cambi, A Franceschini, A Zarbock, A Zarbock, Alessandra Cambi, B Schwanhausser, C Eich, C Laudanna, C Saravanan, Carl G. Figdor, Christina Eich, E Arana, Edwin Lasonder, EJ Ezratty, EY Choi, F Attanasio, F Ye, Fabrizio Mattei, G Bernardini, G Fengos, G Jacquemet, GD Keizer, HY Kueh, Inge Reinieren-Beeren, J Cox, J Cox, J Han, J Rappsilber, JC Kuo, JD Humphries, K Katagiri, K Krauss, K Peter, KJ Borgman, LA Johnson, Luis J. Cruz, M Moser, M Shimaoka, MH Ginsberg, ML Dustin, MM Abdel-Latif, N Hogg, N Tsukamoto, P Cervero, P Gonzalo, P Lajoie, P Mina-Osorio, R Alon, R Lakshminarayan, R Lasserre, R Sampath, R Zaidel-Bar, S Bolte, S Miyamoto, S Ono, SI Buschow, SM Pontier, Sonja I. Buschow, T Geiger, T Lammermann, TS van Zanten, Y Zhang   +61 more
core   +9 more sources

Reclassification of VUS in BRCA1 and BRCA2 using the new BRCA1/BRCA2 ENIGMA track set demonstrates the superiority of ClinGen ENIGMA Expert Panel specifications over the standard ACMG/AMP classification system

Genetics in Medicine Open
Purpose: Variants of uncertain significance (VUS) are considered one of the most significant impediments to the translation of genetic test results into precise clinical recommendations.
Anna Benet-Pagès, Andreas Laner, Luis R. Nassar, Tobias Wohlfrom, Verena Steinke-Lange, Maximilian Haeussler, Elke Holinski-Feder   +6 more
doaj   +1 more source

Analysis of proteins in computational models of synaptic plasticity [PDF]

, 2018
The desire to explain how synaptic plasticity arises from interactions between ions, proteins and other signalling molecules has propelled the development of biophysical models of molecular pathways in hippocampal, striatal and cerebellar synapses.
Armstrong, J Douglas, Heil, Katharina F, Hellgren Kotaleski, Jeanette, Simpson, T Ian, Sorokina, Oksana, Sterratt, David C, Wysocka, Emilia   +6 more
core   +1 more source

Impact of an Alu insertion on the cellular localisation of tissue factor protein

Scientific Reports
Tissue Factor (Hugo Gene Nomenclature Consortium HGNC gene Factor III (F3)) plays vital roles in many cellular processes including haemostasis, thrombosis, inflammation and angiogenesis.
Courtney Chatterton-Bartley, Jun Cao, Joseph Boyle, Dorian Haskard   +3 more
doaj   +1 more source