Human Herpes Virus-6 (HHV-6) Reactivation after Hematopoietic Cell Transplant and Chimeric Antigen Receptor (CAR)- T Cell Therapy: A Shifting Landscape. [PDF]
VirusesHHV-6B reactivation affects approximately half of all allogeneic hematopoietic cell transplant (HCT) recipients. HHV-6B is the most frequent infectious cause of encephalitis following HCT and is associated with pleiotropic manifestations in this setting,
Kampouri E, Handley G, Hill JA.
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Advanced Deep Learning Human Herpes Virus 6 (HHV-6) Molecular Detection in Understanding Human Infertility [PDF]
Computational Intelligence and Neuroscience, 2022 To see if HHV-6 may be a cause of infertility, researchers looked at 18 men and 10 women who had unexplained critical fertility and had at least one prior pregnancy.
Malik Bader Alazzam +4 more
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Tissue specific signature of HHV-6 infection in ME/CFS. [PDF]
Front Mol Biosci, 2022 First exposure to various human herpesviruses (HHVs) including HHV-6, HCMV and EBV does not cause a life-threatening disease. In fact, most individuals are frequently unaware of their first exposure to such pathogens. These herpesviruses acquire lifelong
Kasimir F +5 more
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Detection of HHV-6 Virus in specimen of a ductal pancreatic adenocarcinoma with comparison in tumor and normal tissue [PDF]
Diagnostic Pathology, 2023 Aims The association of human herpesvirus 6 (HHV-6) species with pancreatic cancer is controversially discussed. The aim of this study was to further investigate the postulated association and to identify the basis of HHV-6 DNA positivity reported for ...
S. Warkentin +5 more
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Chorea Associated with HHV-6 Encephalitis
Pediatric Neurology Briefs, 2013 Investigators at Brown University, Providence, RI and other centers in the US and Canada report a 14-month old child with multiple episodes of febrile status epilepticus, followed by chorea and developmental regression, caused by human herpes virus-6 ...
J Gordon Millichap
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Novel marmoset (Callithrix jacchus) model of human Herpesvirus 6A and 6B infections: immunologic, virologic and radiologic characterization. [PDF]
PLoS Pathogens, 2013 Human Herpesvirus 6 (HHV-6) is a ubiquitous virus with an estimated seroprevalence of 95% in the adult population. HHV-6 is associated with several neurologic disorders, including multiple sclerosis, an inflammatory demyelinating disease affecting the ...
Emily Leibovitch +11 more
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Meningoencephalitis in a background of inherited chromosomic integration of HHV-6 and CMV infection in an immunocompetent adult, which one is the culprit? [PDF]
IDCasesHHV-6 meningoencephalitis has been reported in immunocompromised individuals but is very uncommon in immunocompetent individuals. However, HHV-6 is the second most frequently detected virus in multiplex PCR tests. As HHV-6 DNA integrates in the telomeric
Anne-Laure Lajoye +3 more
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Cell Transplantation, 2022 A patient with an ultimate diagnosis of human herpesvirus-6 (HHV-6) encephalitis developed central nervous system (CNS) symptoms 13 days after undergoing myeloablative haploidentical allogeneic hematopoietic stem cell transplant (HSCT).
Harrison Zhu +6 more
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Haematologica, 2019 Of the two human herpesvirus 6 (HHV-6) species, human herpesvirus 6B (HHV-6B) encephalitis is an important cause of morbidity and mortality after allogeneic hematopoietic stem cell transplant. Guidelines for the management of HHV-6 infections in patients
Katherine N Ward +9 more
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GP96 interacts with HHV-6 during viral entry and directs it for cellular degradation.
PLoS ONE, 2014 CD46 and CD134 mediate attachment of Human Herpesvirus 6A (HHV-6A) and HHV-6B to host cell, respectively. But many cell types interfere with viral infection through rapid degradation of viral DNA.
Bhupesh K Prusty +4 more
doaj +3 more sources