Liver international (Print), 2017 Human herpesvirus 6 (HHV-6A and HHV-6B) can cause primary infection or reactivate from latency in liver transplant recipients, which can result in a variety of clinical syndromes, including fever, hepatitis, encephalitis and higher rates of graft ...
Tuan L. Phan +3 more
core +4 more sources
Novel marmoset (Callithrix jacchus) model of human Herpesvirus 6A and 6B infections: immunologic, virologic and radiologic characterization. [PDF]
PLoS Pathogens, 2013 Human Herpesvirus 6 (HHV-6) is a ubiquitous virus with an estimated seroprevalence of 95% in the adult population. HHV-6 is associated with several neurologic disorders, including multiple sclerosis, an inflammatory demyelinating disease affecting the ...
Emily Leibovitch +11 more
doaj +5 more sources
Dominance of variant A in Human Herpesvirus 6 viraemia after renal transplantation [PDF]
Virology Journal, 2011 Background Human herpesvirus 6 (HHV-6), mostly variant B reactivation in renal transplant patients has been published by other authors, but the pathogenetic role of HHV-6 variant A has not been clarified. Our aims were to examine the prevalence of HHV-6,
Csoma Eszter +5 more
doaj +6 more sources
Unique Challenges to Diagnosing Human Herpesvirus-6 (HHV-6) Encephalitis Following Post-Hematopoietic Stem Cell Transplant: A Case and Brief Review [PDF]
Cell Transplantation, 2022 A patient with an ultimate diagnosis of human herpesvirus-6 (HHV-6) encephalitis developed central nervous system (CNS) symptoms 13 days after undergoing myeloablative haploidentical allogeneic hematopoietic stem cell transplant (HSCT).
Harrison Zhu +6 more
doaj +3 more sources
Decreased HHV-6 IgG in Alzheimer’s Disease [PDF]
Frontiers in Neurology, 2017 Human herpesviruses have previously been implicated in the pathogenesis of Alzheimer's disease (AD) but whether they are causal, facilitating, or confounding factors is yet to be established. A total of 50 AD subjects and 52 non-demented (ND) controls were analyzed in a multiplex assay for IgG reactivity toward herpes simplex virus (HSV), varicella ...
Jonas Blomberg +5 more
openaire +3 more sources
The role of HHV-6 and HHV-7 infections in the development of fibromyalgia [PDF]
Journal of Neurovirology, 2019 Funding Information: Funding The work was supported by the project RSU ZP 13/2013: BAssociation of fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome with beta-herpesviruses (HHV-6A, HHV-6B, HHV-7) and parvovirus B19 infection^ (SC ...
Chapenko, Svetlana +9 more
core +4 more sources
Endogenization and excision of human herpesvirus 6 in human genomes. [PDF]
PLoS Genetics, 2020 Sequences homologous to human herpesvirus 6 (HHV-6) are integrated within the nuclear genome of about 1% of humans, but it is not clear how this came about. It is also uncertain whether integrated HHV-6 can reactivate into an infectious virus.
Xiaoxi Liu +22 more
doaj +2 more sources
Human herpesvirus 6 major immediate early promoter has strong activity in T cells and is useful for heterologous gene expression [PDF]
Virology Journal, 2011 Background Human herpesvirus-6 (HHV-6) is a beta-herpesvirus. HHV-6 infects and replicates in T cells. The HHV-6-encoded major immediate early gene (MIE) is expressed at the immediate-early infection phase.
Yamanishi Koichi +3 more
doaj +5 more sources
Haematologica, 2019 Of the two human herpesvirus 6 (HHV-6) species, human herpesvirus 6B (HHV-6B) encephalitis is an important cause of morbidity and mortality after allogeneic hematopoietic stem cell transplant. Guidelines for the management of HHV-6 infections in patients
Katherine N Ward +9 more
doaj +2 more sources
Human herpesvirus 6 infection impairs Toll-like receptor signaling [PDF]
Virology Journal, 2010 Human herpesvirus 6 (HHV-6) has a tropism for immunocompetent cells, including T lymphocytes, monocytes/macrophages, and dendritic cells (DCs) suggesting that HHV-6 infection affects the immunosurveillance system. Toll-like receptor (TLR) system plays an
Ochi Toshiki +7 more
doaj +4 more sources