Results 21 to 30 of about 6,907,620 (239)

Latency, Integration, and Reactivation of Human Herpesvirus-6

Viruses, 2017
Human herpesvirus-6A (HHV-6A) and human herpesvirus-6B (HHV-6B) are two closely related viruses that infect T-cells. Both HHV-6A and HHV-6B possess telomere-like repeats at the terminal regions of their genomes that facilitate latency by integration into
Shara N. Pantry, Peter G. Medveczky
doaj   +1 more source

The case of inherited chromosomal integrated human herpes virus type 6b in child with recurrent respiratory tract infections

Журнал инфектологии, 2020
The five years old boy with recurrent respiratory tract infections was under observation of infectiologist due to high levels of human herpes virus type 6 (HHV-6), found in patient’s blood and saliva during a few years.
M. A. Nikolsky, A. A. Vyazovaya, D. A. Lioznov, O. V. Narvskaya, N. N. Smirnova   +4 more
doaj   +1 more source

Human herpesvirus 6 iInfection in transplantation [PDF]

, 2001
2001-05Human herpesvirus 6 (HHV-6) is ubiquitous in the human population and causes exanthem subitum, a benign disease seen in infancy. The virus remains latent in the body after primary infection, and reactivates in immunocompromised patients. Infection
Yoshikawa, Tetsushi
core   +1 more source

Dominance of variant A in Human Herpesvirus 6 viraemia after renal transplantation

Virology Journal, 2011
Background Human herpesvirus 6 (HHV-6), mostly variant B reactivation in renal transplant patients has been published by other authors, but the pathogenetic role of HHV-6 variant A has not been clarified. Our aims were to examine the prevalence of HHV-6,
Csoma Eszter, Mészáros Beáta, Gáll Tamás, Asztalos László, Kónya József, Gergely Lajos   +5 more
doaj   +1 more source

Development and application of HHV-6 antigen capture assay for the detection of HHV-6 infections

Journal of Virological Methods, 1996
An HHV-6 antigen capture assay measuring gp116/64/54 antigen was developed. This ELISA is specific for HHV-6 Variants A and B, does not cross react with other human herpesviruses, is sensitive, stable, quantitative, and can detect antigen in body fluids and cell cultures.
S, Marsh, M, Kaplan, Y, Asano, D, Hoekzema, A L, Komaroff, J E, Whitman, D V, Ablashi   +6 more
openaire   +2 more sources

Case Report: Inherited chromosomally integrated HHV-6B in a pediatric medulloblastoma patient with encephalitis

Frontiers in Immunology
BackgroundHuman herpesvirus 6B (HHV-6B) is associated with various central nervous system (CNS) disorders, particularly in immunocompromised patients. We present a rare case of inherited chromosomally integrated HHV-6B (iciHHV-6B), also referred to as ...
Scott Sun, Scott Sun, Konstance Knox, Alexander Romashko, Madhu Kundu, Haiying Zhu, Meei-Li Huang, Denise M. Malicki, Denise M. Malicki, John R. Crawford, John R. Crawford, John R. Crawford   +11 more
doaj   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

Xenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Endogenous human herpesviruses 6A/B

Journal of Virology
Human herpesviruses 6A and 6B (HHV-6A/B) can integrate into the germline, resulting in inherited viral DNA—now proposed to be called “endogenous HHV-6A/B (eHHV-6A/B).” Present in 0.2–3% of humans, this integrated DNA is passed to offspring and may ...
Louis Flamand, Jesse Arbuckle, Pascale Bonnafous, Vincent Descamps, Joshua A. Hill, Ruth Jarrett, Keith Jerome, Benedikt B. Kaufer, Rie Koide, Anthony L. Komaroff, Peter Medveczky, Hiroki Miura, Yasuko Mori, Nicholas Parrish, Philip E. Pellett, Michael Wood, Tetsushi Yoshikawa, Danielle M. Zerr   +17 more
doaj   +1 more source

HHV-6A and HHV-6B in Autoimmune Disease

, 2014
A role for HHV-6 has been proposed in several autoimmune disorders (ADs), including multiple sclerosis (MS), autoimmune connective tissue diseases, and Hashimoto's thyroiditis. There are several potential mechanisms by which HHV-6 might induce autoimmune
Francesco Broccolo, BROCCOLO, FRANCESCO
core   +1 more source

Inherited chromosomally integrated human herpesvirus 6: regional variation in prevalence, association with angina, and identification of ancestral viral lineages in two large UK studies

Journal of Virology
Tens of millions of people worldwide have inherited chromosomally integrated human herpesvirus 6 (iciHHV-6), yet we know little about the consequences.
Michael L. Wood, Adam J. Bell, Robin Young, Christopher Brownlie, Nick Orr, Archie Campbell, Jenna Nichols, Konstantinos Papageorgiou, Annette Lake, Nicolas M. Suarez, Katherine Smollett, Natasha Jesudason, Salvatore Camiolo, Sreenu Vattipally, Joseph Hughes, Kirby Brown, Leah M. Hunter, Euan Shaw, Skye Storrie, Rithu Paul Stansilaus, Eillis Sweeney, Tingyi Zhu, Angie Fawkes, Lee Murphy, William Tyne, Philip Howard, Michael E. Jones, Katarzyna Tomczyk, Anne Richmond, James F. Wilson, Duncan A. Clark, Christian Delles, Nicola Royle, Shona M. Kerr, Ana da Silva Filipe, Andrew J. Davison, Alex McConnachie, Anthony J. Swerdlow, Caroline Hayward, Ruth F. Jarrett   +39 more
doaj   +1 more source