Results 1 to 10 of about 1,224 (103)

Transcriptomic profiling of thymic dysregulation and viral tropism after neonatal roseolovirus infection [PDF]

Frontiers in Immunology
IntroductionHerpesviruses, including the roseoloviruses, have been linked to autoimmune disease. The ubiquitous and chronic nature of these infections have made it difficult to establish a causal relationship between acute infection and subsequent ...
Andrei Belean, Eden Xue, Benjamin Cisneros, Elisha D. O. Roberson, Elisha D. O. Roberson, Elisha D. O. Roberson, Michael A. Paley, Michael A. Paley, Tarin M. Bigley, Tarin M. Bigley, Tarin M. Bigley   +10 more
doaj   +7 more sources

Disruption of thymic central tolerance by infection with murine roseolovirus induces autoimmune gastritis [PDF]

Journal of Experimental Medicine, 2022
Infections with herpesviruses, including human roseoloviruses, have been proposed to cause autoimmune disease, but defining a causal relationship and mechanism has been difficult due to the ubiquitous nature of infection and development of autoimmunity long after acute infection.
Tarin M Bigley, Liping Yang, Liang-I Kang   +2 more
exaly   +6 more sources

Past, present, and future perspectives on the diagnosis of Roseolovirus infections [PDF]

Current Opinion in Virology, 2014
Diagnosis of Roseolovirus infections mandates careful selection of patients, samples, and testing methods. We review advances in the field and highlight research priorities. Quantitative (q)PCR can accurately identify and distinguish between human herpesvirus 6 (HHV-6) species A and B.
Joshua A Hill, Ruth Hall Sedlak, Keith R Jérôme   +2 more
exaly   +4 more sources

Porcine Cytomegalovirus/Porcine Roseolovirus, Previously Transmitted During Xenotransplantation, Does Not Infect Human 293T and Mouse Cells with Impaired Antiviral Defense [PDF]

Viruses
Porcine cytomegalovirus, more accurately classified as porcine roseolovirus (PCMV/PRV), was shown to be pathogenic in the context of xenotransplantation.
Hina Jhelum, Reinhold Schäfer, Benedikt B. Kaufer, Joachim Denner   +3 more
doaj   +4 more sources

Mouse Models for Human Herpesviruses [PDF]

Pathogens, 2023
More than one hundred herpesviruses have been isolated from different species so far, with nine infecting humans. Infections with herpesviruses are characterized by life-long latency and represent a significant challenge for human health.
Ivana Kutle, Anne Dittrich, Dagmar Wirth
doaj   +3 more sources

An Approach to Controlling Inflammation and Coagulation in Pig-to-Baboon Cardiac Xenotransplantation. [PDF]

Xenotransplantation
Introduction Inflammatory responses and coagulation disorders are a relevant challenge for successful cardiac xenotransplantation on its way to the clinic. To cope with this, an effective and clinically practicable anti-inflammatory and anti-coagulatory
Bender M, Reichart B, Figueiredo C, Burgmann JM, Leuschen M, Wall F, Radan J, Neumann E, Mokelke M, Buttgereit I, Michel S, Ellgass R, Egerer S, Lange A, Baehr A, Kessler B, Kemter E, Klymiuk N, Denner J, Godehardt AW, Tönjes RR, Hagl C, Gebauer M, Binder U, Skerra A, Ayares D, Wolf E, Schmoeckel M, Brenner P, Längin M, Abicht JM.   +30 more
europepmc   +3 more sources

First virological and pathological study of Göttingen Minipigs with Dippity Pig Syndrome (DPS). [PDF]

PLoS ONE, 2023
Dippity Pig Syndrome (DPS) is a well-known but rare complex of clinical signs affecting minipigs, which has not been thoroughly investigated yet. Clinically affected animals show acute appearance of red, exudating lesions across the spine.
Hina Jhelum, Nanna Grand, Kirsten Rosenmay Jacobsen, Sabrina Halecker, Michelle Salerno, Robert Prate, Luise Krüger, Yannick Kristiansen, Ludwig Krabben, Lars Möller, Michael Laue, Benedikt Kaufer, Kari Kaaber, Joachim Denner   +13 more
doaj   +4 more sources

Detection of human herpesvirus 6 and 7 DNA in saliva from healthy adults from Rio de Janeiro, Brazil [PDF]

Memorias do Instituto Oswaldo Cruz, 2010
In this study, we aimed to evaluate virus shedding in the saliva of healthy adults from the metropolitan region of the city of Rio de Janeiro, Brazil, in order to verify the prevalence of both human herpesviruses 6 and 7 (HHV-6, HHV-7). The studied group
Ivna M Magalhães, Rebeca VN Martins, João J Cossatis, Renata M Cavaliere, Larissa A Afonso, Natalia Moysés, Solange A Oliveira, Silvia MB Cavalcanti   +7 more
doaj   +4 more sources

Active HHV-6 Infection of Cerebellar Purkinje Cells in Mood Disorders [PDF]

Frontiers in Microbiology, 2018
Early-life infections and associated neuroinflammation is incriminated in the pathogenesis of various mood disorders. Infection with human roseoloviruses, HHV-6A and HHV-6B, allows viral latency in the central nervous system and other tissues, which can ...
Bhupesh K. Prusty, Bhupesh K. Prusty, Nitish Gulve, Sheila Govind, Gerhard R. F. Krueger, Julia Feichtinger, Julia Feichtinger, Lee Larcombe, Richard Aspinall, Dharam V. Ablashi, Carla T. Toro, Carla T. Toro   +11 more
doaj   +2 more sources

A Murine Herpesvirus Closely Related to Ubiquitous Human Herpesviruses Causes T-Cell Depletion

Journal of Virology, 2017
The human roseoloviruses human herpesvirus 6A (HHV-6A), HHV-6B, and HHV-7 comprise the Roseolovirus genus of the human Betaherpesvirinae subfamily. Infections with these viruses have been implicated in many
Swapneel J Patel, Guoyan Zhao, Eugene Park   +2 more
exaly   +3 more sources