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Progress of Researches on Central Mechanism of Electroacupuncture Tolerance

针刺研究, 2016
Electroacupuncture(EA)has been demonstrated effective for pain relief.However,repeated application may decline analgesic effect of EA,which is termed EA tolerance,that reduces the clinical efficacy of EA.Therefore,it has attracted attention from ...
CUI Lu-ying, DING Ming-xing
doaj  

Runx3 instructs Aire⁺ mTEC development, TSA gene expression, and central tolerance. [PDF]

J Autoimmun
Sin JH, Phillips SH, Parent AV, Waterfield MR.   +3 more
europepmc   +1 more source

When Central Tolerance Fails: Thymic Malignancies at the Intersection of Cancer Immunity and Autoimmunity. [PDF]

Cancers (Basel)
Abikenari M, Choi J, Enayati I, Tucker A, Bhatnagar K, Chen Y, Himic V, Liu J, Nageeb G, Poe J, Ong SJ, Sanker V, Diehl M, Szeifert V, Terasaki A, Prolo LM, Engleman E, Okwan-Duodu D.   +17 more
europepmc   +1 more source

Claudin 1-mediated positioning of DC1 to mTECs is essential for maintenance of central tolerance. [PDF]

J Exp Med
Březina J, Brabec T, Machač D, Vobořil M, Ballek O, Pačes J, Sýkora V, Jančovičová K, Valter E, Kováčová K, Manning J, Tahtahová V, Čepková A, Dobešová M, Dobeš J, Kubovčiak J, Kolář M, Kašpárek P, Sedlacek R, Štepánek O, Černý J, Tsukita S, Malissen B, Anderson G, Filipp D.   +24 more
europepmc   +1 more source

Aire-dependent interferon signalling shapes thymocyte maturation and central tolerance in mice. [PDF]

Commun Biol
Jebrzycka A, Breivik L, Dolan D, Goldfarb Y, Abramson J, Wolff ASB, Husebye ES, Joshi A, Oftedal BE.   +8 more
europepmc   +1 more source

Absence of central tolerance in Aire-deficient mice synergizes with immune-checkpoint inhibition to enhance antitumor responses. [PDF]

Commun Biol, 2020
Benitez AA, Khalil-Agüero S, Nandakumar A, Gupta NT, Zhang W, Atwal GS, Murphy AJ, Sleeman MA, Haxhinasto S.   +8 more
europepmc   +1 more source

B7-CD28 co-stimulation modulates central tolerance via thymic clonal deletion and Treg generation through distinct mechanisms. [PDF]

Nat Commun, 2020
Watanabe M, Lu Y, Breen M, Hodes RJ.
europepmc   +1 more source

Permissive central tolerance plus defective peripheral checkpoints license pathogenic memory B cells in CASPR2-antibody encephalitis. [PDF]

Sci Adv
Sun B, Fernandes D, Soltys J, Kienzler AK, Paneva S, Harrison R, Ramanathan S, Harrison AL, Makuch M, Fichtner ML, Donat RF, Akdeniz D, Bayuangga H, Im MG, Williams R, Vasconcelos A, Thomsen S, Fower A, Sun R, Fox H, Mgbachi V, Davies A, Tseng M, Handel A, Kelly M, Zhao M, Bancroft J, Bashford-Rogers R, Pluvinage JV, Dandekar R, Alvarenga BD, Dustin LB, Rinaldi S, Owens R, Anthony D, Bennett DL, Waters P, Davis SJ, Wilson MR, O'Connor KC, Carvalho AL, Irani SR.   +41 more
europepmc   +1 more source

Functionally diverse thymic medullary epithelial cells interplay to direct central tolerance. [PDF]

Cell Rep
Ushio A, Matsuda-Lennikov M, Kalle-Youngoue F, Shimizu A, Abdelmaksoud A, Kelly MC, Ishimaru N, Takahama Y.   +7 more
europepmc   +1 more source

Central tolerance shapes the neutralizing B cell repertoire against a persisting virus in its natural host. [PDF]

Proc Natl Acad Sci U S A
Florova M, Abreu-Mota T, Paesen GC, Beetschen AS, Cornille K, Marx AF, Narr K, Sahin M, Dimitrova M, Swarnalekha N, Beil-Wagner J, Savic N, Pelczar P, Buch T, King CG, Bowden TA, Pinschewer DD.   +16 more
europepmc   +1 more source