Results 1 to 10 of about 960,253 (307)
Non-structural proteins of arthropod-borne bunyaviruses: roles and functions [PDF]
, 2013 Viruses within the Bunyaviridae family are tri-segmented, negative-stranded RNA viruses. The family includes several emerging and re-emerging viruses of humans, animals and plants, such as Rift Valley fever virus, Crimean-Congo hemorrhagic fever virus ...
Alain Kohl +17 more
core +3 more sources
Modulation of antigen-specific T-cells as immune therapy for chronic infectious diseases and cancer [PDF]
, 2014 Copyright: © 2014 Li, Symonds, Miao, Sanderson and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Abraham +55 more
core +2 more sources
Chronic Active Epstein-Barr Virus Infection
Uirusu, 2011 The ubiquitous Epstein-Barr virus (EBV), which establishes latency after primary infection, does not cause any symptomatic diseases as long as cellular immunity is intact. In apparently immunocompetent individuals, a chronic infection can develop, and this has been called as chronic active EBV infection (CAEBV).
openaire +3 more sources
Emerging Infectious Diseases, 2019 Ebola virus disease (EVD) is associated with elevated cytokine levels, and hypercytokinemia is more pronounced in fatal cases. This type of hyperinflammatory state is reminiscent of 2 rheumatologic disorders known as macrophage activation syndrome and ...
Anita K. McElroy +13 more
doaj +1 more source
Quantitative subcellular proteome and secretome profiling of influenza A virus-infected human primary macrophages. [PDF]
PLoS Pathogens, 2011 Influenza A viruses are important pathogens that cause acute respiratory diseases and annual epidemics in humans. Macrophages recognize influenza A virus infection with their pattern recognition receptors, and are involved in the activation of proper ...
Niina Lietzén +6 more
doaj +1 more source
Fresh Insights into Disease Etiology and the Role of Microbial Pathogens. [PDF]
, 2016 Pathogens have been implicated in the initiation and/or promotion of systemic sclerosis (scleroderma, SSc); however, no evidence was found to substantiate the direct contribution to this disease in past years.
FARINA, Antonella, Farina, G.a.2.
core +1 more source
Peptide Bbeta(15-42) preserves endothelial barrier function in shock [PDF]
, 2009 Loss of vascular barrier function causes leak of fluid and proteins into tissues, extensive leak leads to shock and death. Barriers are largely formed by endothelial cell-cell contacts built up by VE-cadherin and are under the control of RhoGTPases. Here
Atrasheuskaya, Alena +12 more
core
A study on the relationship between HCV NS3 and endogenous IRF-3
European Journal of Inflammation, 2018 This study aims to investigate the relationship between hepatitis C virus (HCV) NS3/4A and endogenous interferon regulatory factor-3 (IRF-3). The localization of endogenous IRF-3 protein before and after virus infection was analyzed by immunofluorescence
Hong-Ping Liang, Hotta Hak, Jian-Min Ji
doaj +1 more source
Activation of One Plant Virus by Another
Nature, 1960 TOBACCO necrosis is a disease that can be caused by several serologically unrelated viruses1, all of which are soil-borne and cause necrotic local lesions in leaves of tobacco (Nicotiana tabacum L.) and French bean (Phaseolus vulgaris L.) plants. The virus Bawden and Pirie2,3 called the ‘Rothamsted culture’ differed in several respects from other ...
Kassanis, B., Nixon, H. L.
openaire +2 more sources
DYRK4 upregulates antiviral innate immunity by promoting IRF3 activation
EMBO ReportsViral infection activates the transcription factors IRF3 and NF-κB, which induce type I interferon (IFN) and antiviral innate immune responses. Here, we identify dual-specific tyrosine phosphorylation-regulated kinase 4 (DYRK4) as an important regulator ...
Xianhuang Zeng +8 more
doaj +1 more source