A Nomogram for Predicting BK Virus Activation in Kidney Transplantation Recipients Using Clinical Risk Factors [PDF]
Frontiers in Medicine, 2022 BK virus is a common opportunistic viral infection that could cause BK virus-associated nephropathy in renal transplant recipients. Thus, we retrospectively analyzed clinical and laboratory data associated with a higher risk of BK virus activation from ...
Jiyan Wang +14 more
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Activation of Inflammasome during Bluetongue Virus Infection
Pathogens, 2023 Bluetongue virus (BTV), a double-stranded RNA virus belonging to the Sedoreoviridae family, provokes an economically important disease in ruminants.
Marie Pourcelot +5 more
doaj +3 more sources
Clinical Case Reports, 2021 Psoriasis is a chronic inflammatory disease with characteristic skin manifestations. Several pathogens can cause flare‐ups of psoriasis. The risks of skin infections are increased in patients receiving immunomodulators.
Wu‐Feng Hsieh +5 more
doaj +1 more source
Diversity in Proprotein Convertase Reactivity among Human Papillomavirus Types
Viruses, 2023 The cleavage of viral surface proteins by furin is associated with some viruses’ high virulence and infectivity. The human papillomavirus (HPV) requires the proteolytic processing of its capsid proteins for activation before entry.
Gonzalo Izaguirre +5 more
doaj +1 more source
Hepatitis B screening rates and reactivation in solid organ malignancy patients undergoing chemotherapy in Southern Thailand [PDF]
Clinical and Molecular Hepatology, 2019 Background/Aims Hepatitis B virus reactivation (HBVr) following chemotherapy (CMT) is well-known among hematologic malignancies, and screening recommendations are established. However, HBVr data in solid organ malignancy (SOM) patients are limited.
Ratchapong Laiwatthanapaisan +7 more
doaj +1 more source
Regulation of PI3K/Akt dependent apoptotic markers during b virus infection of human and macaque fibroblasts. [PDF]
PLoS ONE, 2017 B virus (Macacine herpesvirus 1), a simplex virus endemic in macaques, causes encephalitis, encephalomyelitis, and death in 80% of untreated zoonotically infected humans with delayed or no treatment.
Mugdha Vasireddi, Julia K Hilliard
doaj +1 more source
Differential activation of human neutrophils by SARS-CoV-2 variants of concern
Frontiers in Immunology, 2022 The emerging SARS-CoV-2 virus has affected the entire world with over 600 million confirmed cases and 6.5 million deaths as of September 2022. Since the beginning of the pandemic, several variants of SARS-CoV-2 have emerged, with different infectivity ...
Samuel Lebourgeois +19 more
doaj +1 more source
The virion host shut-off (vhs) protein blocks a TLR-independent pathway of herpes simplex virus type 1 recognition in human and mouse dendritic cells. [PDF]
PLoS ONE, 2010 Molecular pathways underlying the activation of dendritic cells (DCs) in response to Herpes Simplex Virus type 1 (HSV-1) are poorly understood. Removal of the HSV virion host shut-off (vhs) protein relieves a block to DC activation observed during wild ...
Christopher R Cotter +5 more
doaj +1 more source
Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication. [PDF]
PLoS Pathogens, 2017 Influenza A virus usurps host signaling factors to regulate its replication. One example is mTOR, a cellular regulator of protein synthesis, growth and motility.
Sharon K Kuss-Duerkop +13 more
doaj +1 more source
Mast Cells Modulate Antigen-Specific CD8+ T Cell Activation During LCMV Infection
Frontiers in Immunology, 2021 Mast cells (MCs), strategically localized at mucosal surfaces, provide first-line defense against pathogens and shape innate and adaptive immune responses.
Yana Hackler +6 more
doaj +1 more source