Results 21 to 30 of about 615,631 (266)
Porcine Trypsin in the Manufacture of Biological Medicinal Products. Risks and Safety Requirements
Биопрепараты: Профилактика, диагностика, лечение, 2018 Trypsin is a reagent widely used in the manufacture of biological medicinal products (BMPs). Until recently, pancreata of cattle, pigs and poultry were the main sources of trypsin preparations. The discovery of the disease called «transmissive spongiform
S. M. Sukhanov, E. M. Petruchuk
doaj +1 more source
The Haemagglutinating Activity of Berne Virus
Journal of General Virology, 1986 Berne virus possesses haemagglutinating activity which is inhibited by antisera that neutralize the infectivity of the virus. In decreasing order, human, rabbit and guinea-pig erythrocytes were agglutinated whereas agglutination was not observed with rat, goose, chicken or horse red blood cells. This pattern is different from that seen with the closely
R, Zanoni, M, Weiss, E, Peterhans
openaire +2 more sources
Trypsin. Properties and Use in the Production of Biological Medicinal Products
Биопрепараты: Профилактика, диагностика, лечение, 2018 The production of biological medicinal products used for prophylactic, diagnostic and therapeutic purposes includes the use of inherently variable biological processes and materials.
S. M. Sukhanova +2 more
doaj +1 more source
The actin nucleator Spir-1 is a virus restriction factor that promotes innate immune signalling.
PLoS Pathogens, 2022 Cellular proteins often have multiple and diverse functions. This is illustrated with protein Spir-1 that is an actin nucleator, but, as shown here, also functions to enhance innate immune signalling downstream of RNA sensing by RIG-I/MDA-5. In human and
Alice A Torres +6 more
doaj +1 more source
Activation thermodynamics of virus adsorption to solids [PDF]
Applied and Environmental Microbiology, 1988 The kinetics of bacteriophage MS2, T2, and f2 adsorption to powdered nitrocellulose and disrupted Seitz S1 filters at pH 7 were determined as a function of temperature. Data from these studies were combined with data produced in a previous study on MS2 adsorption to clay by Stagg et al. (Appl. Environ. Microbiol. 33:385-391, 1977).
D R, Preston, S R, Farrah
openaire +2 more sources
Cell Reports, 2016 Host response to RNA virus infection is sensed by RNA sensors such as RIG-I, which induces MAVS-mediated NF-κB and IRF3 activation to promote inflammatory and antiviral responses, respectively.
Changying Jiang +10 more
doaj +1 more source
Influenza Virus-Induced Oxidized DNA Activates Inflammasomes
iScience, 2020 Summary: Influenza virus M2 and PB1-F2 proteins have been proposed to activate the Nod-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome in macrophages by altering intracellular ionic balance or mitochondrial reactive oxygen species ...
Miyu Moriyama +5 more
doaj +1 more source
Resting regulatory CD4 T cells: a site of HIV persistence in patients on long-term effective antiretroviral therapy. [PDF]
PLoS ONE, 2008 BACKGROUND: In HIV-infected patients on long-term HAART, virus persistence in resting long-lived CD4 T cells is a major barrier to curing the infection.
Tu-Anh Tran +11 more
doaj +1 more source
Inter-domain communication in SARS-CoV-2 spike proteins controls protease-triggered cell entry
Cell Reports, 2022 Summary: SARS-CoV-2 continues to evolve into variants of concern (VOC), with greatest variability in the multidomain, entry-facilitating spike proteins. To recognize the significance of adaptive spike protein changes, we compare variant SARS-CoV-2 virus ...
Enya Qing +7 more
doaj +1 more source
Flavonoids as Molecules With Anti-Zika virus Activity [PDF]
Frontiers in Microbiology, 2021 Zika virus (ZIKV) is an arthropod-born virus that is mainly transmitted to humans by mosquitoes of the genus Aedes spp. Since its first isolation in 1947, only a few human cases had been described until large outbreaks occurred on Yap Island (2007), French Polynesia (2013), and Brazil (2015).
Depieri Cataneo, Allan Henrique +10 more
openaire +4 more sources