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Estrogen and viral infection. [PDF]

open access: yesFront Immunol
Gender differences exist in the susceptibility, incidence, progression, and prognosis of diseases caused by viral infections. These differences are influenced by various factors, including lifestyle and habits between males and females. Some reports have pointed out that estrogen plays an important immune-modulatory role in many viral infections.
Wei X   +6 more
europepmc   +4 more sources

Viral infections [PDF]

open access: yesJournal of Clinical Pathology, 1976
Although rubella is the only virus which can be regarded in the strict sense of the term a teratogen, there is no convincing evidence that other viruses can cause fetal damage of varying severity. The risk to the fetus appears to depend on the nature of the infectious agent, the maternal immune status and the gestational age when infection takes place.
L, Weinstein, T W, Chang
openaire   +5 more sources

Defining basic rules for hardening influenza A virus liquid condensates

open access: yeseLife, 2023
In biological systems, liquid and solid-like biomolecular condensates may contain the same molecules but their behaviour, including movement, elasticity, and viscosity, is different on account of distinct physicochemical properties.
Temitope Akhigbe Etibor   +9 more
doaj   +1 more source

Increased Production of Inflammatory Cytokines after Inoculation with Recombinant Zoster Vaccine in Mice

open access: yesVaccines, 2022
Increasing numbers of patients with zoster were reported recently, and recombinant zoster vaccine (Shingrix®) was licensed using the AS01B adjuvant system.
Tetsuo Nakayama   +2 more
doaj   +1 more source

Neurogenesis and Viral Infection [PDF]

open access: yesFrontiers in Immunology, 2022
Neural stem cells (NSCs) are multipotent stem cells that reside in the fetal and adult mammalian brain, which can self-renew and differentiate into neurons and supporting cells. Intrinsic and extrinsic cues, from cells in the local niche and from distant sites, stringently orchestrates the self-renewal and differentiation competence of NSCs.
Ihunwo A. O.   +4 more
openaire   +4 more sources

Fibroblasts are a site of murine cytomegalovirus lytic replication and Stat1-dependent latent persistence in vivo

open access: yesNature Communications, 2023
To date, no herpesvirus has been shown to latently persist in fibroblastic cells. Here, we show that murine cytomegalovirus, a β-herpesvirus, persists for the long term and across organs in PDGFRα-positive fibroblastic cells, with similar or higher ...
Katarzyna M. Sitnik   +8 more
doaj   +1 more source

Chimeric Measles Virus (MV/RSV), Having Ectodomains of Respiratory Syncytial Virus (RSV) F and G Proteins Instead of Measles Envelope Proteins, Induced Protective Antibodies against RSV

open access: yesVaccines, 2021
In our previous study, fusion (F) or glyco (G) protein coding sequence of respiratory syncytial virus (RSV) was inserted at the P/M junction of the measles AIK-C vector (MVAIK), and the recombinant measles virus induced protective immune responses.
Akihito Sawada   +3 more
doaj   +1 more source

Diminished neutralization responses towards SARS-CoV-2 Omicron VoC after mRNA or vector-based COVID-19 vaccinations

open access: yesScientific Reports, 2022
SARS-CoV-2 variants accumulating immune escape mutations provide a significant risk to vaccine-induced protection against infection. The novel variant of concern (VoC) Omicron BA.1 and its sub-lineages have the largest number of amino acid alterations in
Henning Jacobsen   +29 more
doaj   +1 more source

Cytokine and Chemokine Production in Mice Inoculated with NVX-CoV2373 (Nuvaxovid®) in Comparison with Omicron BA.4/5 Bivalent BNT162b2 (Comirnaty®)

open access: yesVaccines, 2023
A recombinant SARS-CoV-2 spike protein vaccine (NVX-CoV2373) has been licensed and has a lesser incidence of adverse events. To know the immunological mechanisms of adverse events, the production of cytokines and chemokines was investigated in mice ...
Tetsuo Nakayama   +3 more
doaj   +1 more source

Immunosuppression in Viral Infections [PDF]

open access: yesClinical Infectious Diseases, 1986
Viruses may cause immunosuppression by a variety of mechanisms. This review delineates four categories. First, immunosuppression can result from the direct effects of viral replication on lymphocyte functions. Either all classes of lymphocytes can be affected, as occurs in measles, or the effect can be restricted to a cell subtype, as is the case with ...
B T, Rouse, D W, Horohov
openaire   +2 more sources

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