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TMPRSS2 Is Essential for SARS-CoV-2 Beta and Omicron Infection
Viruses, 2023 The COVID-19 pandemic remains a global health threat and novel antiviral strategies are urgently needed. SARS-CoV-2 employs the cellular serine protease TMPRSS2 for entry into lung cells, and TMPRSS2 inhibitors are being developed for COVID-19 therapy ...
Kristin Metzdorf +13 more
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The nucleolus and viral infection [PDF]
Virologica Sinica, 2010 The nucleolus is a subnuclear structure of eukaryocytes. It was thought that nucleolus only participates in the biogenesis and processing of rRNA. However, more and more evidence shows that it has many other functions, such as tRNA precursor processing, stress sensing and it is also involved in gene silencing, senescence and cell cycle regulation. Here,
Wang, Lei +3 more
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One Step Ahead: Herpesviruses Light the Way to Understanding Interferon-Stimulated Genes (ISGs)
Frontiers in Microbiology, 2020 The host immune system is engaged in a constant battle with microorganisms, with the immediate detection of pathogenic invasion and subsequent signalling acting as crucial deterrents against the establishment of a successful infection.
A. Cristina Gonzalez-Perez +5 more
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Frontiers in Immunology, 2023 IntroductionThe evolution of novel SARS-CoV-2 variants significantly affects vaccine effectiveness. While these effects can only be studied retrospectively, neutralizing antibody titers are most used as correlates of protection.
Maeva Katzmarzyk +12 more
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Postgraduate Medical Journal, 2004 Abstract Dengue viral infections are one of the most important mosquito borne diseases in the world. They may be asymptomatic or may give rise to undifferentiated fever, dengue fever, dengue haemorrhagic fever (DHF), or dengue shock syndrome.
G N, Malavige +3 more
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BMC Infectious Diseases, 2019 Background Human papillomavirus (HPV) causes cancers in men, including penile, anal, and oropharyngeal cancers. This cross-sectional study aimed to investigate the prevalence, the genotypes, and the risk factors of HPV infections in the oral cavity ...
Hai Ha Long Le +5 more
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Liquid Biomolecular Condensates and Viral Lifecycles: Review and Perspectives
Viruses, 2021 Viruses are highly dependent on the host they infect. Their dependence triggers processes of virus–host co-adaptation, enabling viruses to explore host resources whilst escaping immunity.
Temitope Akhigbe Etibor +2 more
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Indian Journal of Dermatology, 2010 Dengue viral infections are one of the most important mosquito-borne diseases in the world. Presently dengue is endemic in 112 countries in the world. It has been estimated that almost 100 million cases of dengue fever and half a million cases of dengue hemorrhagic fever (DHF) occur worldwide. An increasing proportion of DHF is in children less than 15
Gurugama Padmalal +4 more
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Current Opinion in Infectious Diseases, 1998 This section should be of particular interest to the travel medicine physician as it reports many new manifestations of exotic viral infections, both in terms of new clinical expression or extension to new geographical territory. Included are descriptions of improved diagnostic methodologies for arboviral diseases, a discussion of safety issues ...
T F, Tsai, S B, Halstead
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Vaccines, 2019 We previously reported that recombinant measles virus expressing the respiratory syncytial virus (RSV) fusion protein (F), MVAIK/RSV/F, induced neutralizing antibodies against RSV, and those expressing RSV-NP (MVAIK/RSV/NP) and M2-1 (MVAIK/RSV/M2-1 ...
Yoshiaki Yamaji +4 more
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