Respiratory syncytial virus and neutrophil activation [PDF]
Clinical and Experimental Immunology, 2005 SummaryRespiratory syncytial virus infects almost all children by 2 years of age. Neutrophils are the predominant airway leucocytes in RSV bronchiolitis and they are activated in the presence of infection. However it is not clear whether RSV can directly signal to activate neutrophil cytotoxic function. To investigate this we have used a preparation of
E L, Bataki, G S, Evans, M L, Everard
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Trypsin. Properties and Use in the Production of Biological Medicinal Products
Биопрепараты: Профилактика, диагностика, лечение, 2018 The production of biological medicinal products used for prophylactic, diagnostic and therapeutic purposes includes the use of inherently variable biological processes and materials.
S. M. Sukhanova +2 more
doaj +1 more source
A fatal case of hepatitis B virus (HBV) reactivation during long-term, very-low-dose steroid treatment in an inactive HBV carrier [PDF]
Clinical and Molecular Hepatology, 2012 Hepatitis B virus (HBV) may be reactivated after chemotherapy or immunosuppressive therapy, and therefore administration of antiviral agents before such treatment is recommended.
Joong Ho Bae +8 more
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Has HIV evolved to induce immune pathogenesis? [PDF]
, 2008 Human immunodeficiency virus (HIV) induces a chronic generalized activation of the immune system, which plays an important role in the pathogenesis of AIDS.
Bartha, István +2 more
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Assembly and architecture of the EBV B cell entry triggering complex. [PDF]
, 2014 Epstein-Barr Virus (EBV) is an enveloped double-stranded DNA virus of the gammaherpesvirinae sub-family that predominantly infects humans through epithelial cells and B cells.
Chen, Jia +10 more
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Porcine Trypsin in the Manufacture of Biological Medicinal Products. Risks and Safety Requirements
Биопрепараты: Профилактика, диагностика, лечение, 2018 Trypsin is a reagent widely used in the manufacture of biological medicinal products (BMPs). Until recently, pancreata of cattle, pigs and poultry were the main sources of trypsin preparations. The discovery of the disease called «transmissive spongiform
S. M. Sukhanov, E. M. Petruchuk
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Generation of virus-specific cytotoxic T cells in vitro I. Induction conditions of primary and secondary Sendai virus-specific cytotoxic T cells [PDF]
, 1979 H-2-restricted cytotoxic T cells specific for Sendai virus were generated in vitro in a primary response from normal mouse lymphocytes cultured in the presence of infective as well as inactivated Sendai virus. Antigen-presenting cells of different origin,
Andersson +41 more
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An investigation of herpes simplex virus promoter activity compatible with latency establishment reveals VP16-independent activation of immediate-early promoters in sensory neurones [PDF]
, 2011 Herpes simplex virus (HSV) type-1 establishes lifelong latency in sensory neurones and it is widely assumed that latency is the consequence of a failure to initiate virus immediate-early (IE) gene expression. However, using a Ore reporter mouse system in
Arthur, J. +6 more
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Influenza Virus-Induced Oxidized DNA Activates Inflammasomes
iScience, 2020 Summary: Influenza virus M2 and PB1-F2 proteins have been proposed to activate the Nod-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome in macrophages by altering intracellular ionic balance or mitochondrial reactive oxygen species ...
Miyu Moriyama +5 more
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The actin nucleator Spir-1 is a virus restriction factor that promotes innate immune signalling.
PLoS Pathogens, 2022 Cellular proteins often have multiple and diverse functions. This is illustrated with protein Spir-1 that is an actin nucleator, but, as shown here, also functions to enhance innate immune signalling downstream of RNA sensing by RIG-I/MDA-5. In human and
Alice A Torres +6 more
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