Results 31 to 40 of about 615,631 (266)

Interferon-beta pretreatment of conventional and plasmacytoid human dendritic cells enhances their activation by influenza virus. [PDF]

PLoS Pathogens, 2008
Influenza virus produces a protein, NS1, that inhibits infected cells from releasing type I interferon (IFN) and blocks maturation of conventional dendritic cells (DCs).
Hannah Phipps-Yonas, Jeremy Seto, Stuart C Sealfon, Thomas M Moran, Ana Fernandez-Sesma   +4 more
doaj   +1 more source

Activation of One Plant Virus by Another

Nature, 1960
TOBACCO necrosis is a disease that can be caused by several serologically unrelated viruses1, all of which are soil-borne and cause necrotic local lesions in leaves of tobacco (Nicotiana tabacum L.) and French bean (Phaseolus vulgaris L.) plants. The virus Bawden and Pirie2,3 called the ‘Rothamsted culture’ differed in several respects from other ...
Kassanis, B., Nixon, H. L.
openaire   +2 more sources

Respiratory syncytial virus and neutrophil activation [PDF]

Clinical and Experimental Immunology, 2005
SummaryRespiratory syncytial virus infects almost all children by 2 years of age. Neutrophils are the predominant airway leucocytes in RSV bronchiolitis and they are activated in the presence of infection. However it is not clear whether RSV can directly signal to activate neutrophil cytotoxic function. To investigate this we have used a preparation of
E L, Bataki, G S, Evans, M L, Everard
openaire   +2 more sources

Endosymbiotic RNA virus inhibits Leishmania-induced caspase-11 activation

iScience, 2021
Summary: New World species of the intracellular protozoan parasites of the Leishmania genus can cause mucocutaneous leishmaniases. The presence of an endosymbiotic Leishmania RNA virus (LRV) in Leishmania guyanensis (L.g.) promotes disease exacerbation ...
Renan V.H. de Carvalho, Djalma S. Lima-Júnior, Caroline V. de Oliveira, Dario S. Zamboni   +3 more
doaj   +1 more source

Microassay for Sindbis virus and interferon activity [PDF]

Journal of Clinical Microbiology, 1983
A simple and rapid microplaque assay for Sindbis virus was developed which uses microtiter plates and overlay medium consisting of methylcellulose and specific antibody to Sindbis virus. Discrete plaque formation was consistently observed on baby hamster kidney (BHK-15) cells within 24 h. The assay was reproducible, quantitative, and had about the same
R E, Lloyd, D A, Weigent, G J, Stanton
openaire   +2 more sources

Activation of TLR4 by viral glycoproteins: A double-edged sword?

Frontiers in Microbiology, 2022
Recognition of viral infection by pattern recognition receptors is paramount for a successful immune response to viral infection. However, an unbalanced proinflammatory response can be detrimental to the host.
Emily A. Halajian, Emmanuelle V. LeBlanc, Katrina Gee, Che C. Colpitts   +3 more
doaj   +1 more source

Map3k14 as a Regulator of Innate and Adaptive Immune Response during Acute Viral Infection

Pathogens, 2020
The replication of virus in secondary lymphoid organs is crucial for the activation of antigen-presenting cells. Balanced viral replication ensures the sufficient availability of antigens and production of cytokines, and both of which are needed for ...
Thamer A. Hamdan, Hilal Bhat, Lamin B. Cham, Tom Adomati, Judith Lang, Fanghui Li, Ali Murtaza, Cornelia Hardt, Philipp A. Lang, Vikas Duhan, Karl S. Lang   +10 more
doaj   +1 more source

Autophagic machinery activated by dengue virus enhances virus replication

Virology, 2008
Autophagy is a cellular response against stresses which include the infection of viruses and bacteria. We unravel that Dengue virus-2 (DV2) can trigger autophagic process in various infected cell lines demonstrated by GFP-LC3 dot formation and increased LC3-II formation.
Lee, Ying-Ray, Lei, Huan-Yao, Liu, Ming-Tao, Wang, Jen-Ren, Chen, Shun-Hua, Jiang-Shieh, Ya-Fen, Lin, Yee-Shin, Yeh, Trai-Ming, Liu, Ching-Chuan, Liu, Hsiao-Sheng   +9 more
openaire   +2 more sources

Locus-specific proteomics identifies novel regulators of Epstein-Barr virus lytic reactivation

Journal of Virology
The Epstein-Barr virus (EBV) is a human gamma-herpesvirus which infects over 90% of the global population and is associated with lymphoid and epithelioid cancers. After infection, EBV enters a latent state in B cells, whereby the viral genome persists as
Daniel E. Greaves, Ildar Gabaev, James C. Williamson, Stuart Bloor, Sergio Martinez Cuesta, Nicholas J. Matheson, Lori Frappier, Jérôme Déjardin, Paul J. Lehner   +8 more
doaj   +1 more source

Virus-based vaccine vectors with distinct replication mechanisms differentially infect and activate dendritic cells

npj Vaccines, 2021
The precise mechanism by which many virus-based vectors activate immune responses remains unknown. Dendritic cells (DCs) play key roles in priming T cell responses and controlling virus replication, but their functions in generating protective immunity ...
Carolina Chiale, Anthony M. Marchese, Yoichi Furuya, Michael D. Robek   +3 more
doaj   +1 more source