Status of F-18 fluorodeoxyglucose uptake in normal and hibernating myocardium after glucose and insulin loading [PDF]
Objective: F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) has been increasingly used in myocardial viability imaging. In routine PET viability studies, oral glucose and intravenous insulin loading is commonly utilized.
Ismet Sarikaya +4 more
doaj +4 more sources
Stunned and Hibernating Myocardium: Where Are We Nearly 4 Decades Later? [PDF]
T he concepts of stunned and hibernating myocardium were described and received considerable attention in the 1980s. These phenomena, related to myocardial ischemia (Figure 1), occur far more frequently than when they were initially described.
Robert A. Kloner
doaj +4 more sources
Novel Therapeutic Approaches Enhance PGC1-alpha to Reduce Oxidant Stress-Inflammatory Signaling and Improve Functional Recovery in Hibernating Myocardium [PDF]
Ischemic heart disease affects millions of people around the world. Current treatment options, including coronary artery bypass grafting, do not result in full functional recovery, highlighting the need for novel adjunctive therapeutic approaches ...
Rishav Aggarwal +4 more
doaj +3 more sources
The aim of this prospective study was to explore the feasibility of 18F-fluoromisonidazole (18F-FMISO) cardiac positron emission tomography/computed tomography (PET/CT) in the detection of cardiac hypoxia in patients of ischemic heart disease (IHD) and ...
Rajlaxmi Jagtap +2 more
doaj +3 more sources
An Adjuvant Stem Cell Patch with Coronary Artery Bypass Graft Surgery Improves Diastolic Recovery in Porcine Hibernating Myocardium. [PDF]
Diastolic dysfunction persists despite coronary artery bypass graft surgery (CABG) in patients with hibernating myocardium (HIB). We studied whether the adjunctive use of a mesenchymal stem cells (MSCs) patch during CABG improves diastolic function by ...
Aggarwal R +11 more
europepmc +4 more sources
Global intracoronary infusion of allogeneic cardiosphere-derived cells improves ventricular function and stimulates endogenous myocyte regeneration throughout the heart in swine with hibernating myocardium. [PDF]
Cardiosphere-derived cells (CDCs) improve ventricular function and reduce fibrotic volume when administered via an infarct-related artery using the "stop-flow" technique.
Gen Suzuki +6 more
doaj +3 more sources
Cardiomyocyte Remodeling in Atrial Fibrillation and Hibernating Myocardium: Shared Pathophysiologic Traits Identify Novel Treatment Strategies? [PDF]
Atrial fibrillation (AF) is the most common arrhythmia and is associated with a high risk of morbidity and mortality. However, there are limited treatment strategies for prevention of disease onset and progression.
Weil BR, Ozcan C.
europepmc +4 more sources
Is there an association between hibernating myocardium and left ventricular mechanical dyssynchrony in patients with myocardial infarction? [PDF]
Zhang F +10 more
europepmc +4 more sources
Association between hibernating myocardium and collateral circulation in patients with coronary chronic total occlusion [PDF]
ObjectiveTo explore the association between the quantity of hibernating myocardium (HM) and collateral circulation in patients with coronary chronic total occlusion (CTO).Materials and methods88 CTO patients were retrospectively analyzed who underwent ...
Yaqi Liu +14 more
doaj +2 more sources
Myocardial Viability: Evolving Insights and Challenges in Revascularization and Functional Recovery [PDF]
The prevalence of heart failure, driven significantly by ischemic heart disease, continues to rise globally. Myocardial viability—the potential ability of dysfunctional myocardium to recover contractile function after revascularization—remains an ongoing
Kristoffer Ken Ralota +3 more
doaj +2 more sources

