Results 51 to 60 of about 12,269 (201)

Hibernating ribosomes as drug targets?

Frontiers in Microbiology
When ribosome-targeting antibiotics attack actively growing bacteria, they occupy ribosomal active centers, causing the ribosomes to stall or make errors that either halt cellular growth or cause bacterial death. However, emerging research indicates that
Chinenye L. Ekemezie, Sergey V. Melnikov, Sergey V. Melnikov   +2 more
doaj   +1 more source

Bioclimatic, demographic and anthropogenic correlates of grizzly bear activity patterns in the Greater Yellowstone Ecosystem

Oikos, EarlyView.
Plasticity of diel activity rhythms may be a key element for adaptations of wildlife populations to changing environmental conditions. In the last decades, grizzly bears Ursus arctos in the Greater Yellowstone Ecosystem (GYE) have experienced notable environmental fluctuations, including changes in availability of food sources and severe droughts ...
Aurora Donatelli, Mark A. Haroldson, Justin G. Clapp, Paolo Ciucci, Frank T. van Manen   +4 more
wiley   +1 more source

Convergent accelerated evolution of mammal-specific conserved non-coding elements in hibernators

Scientific Reports
Mammals maintain their body temperature, yet hibernators can temporarily lower their metabolic rate as an energy-saving strategy. It has been proposed that hibernators evolved independently from homeotherms, and it is possible that the convergent ...
Daiki Nakayama, Takashi Makino
doaj   +1 more source

The paddy frog genome provides insight into the molecular adaptations and regulation of hibernation in ectotherms

iScience
Summary: Amphibians, like the paddy frog (Fejervarya multistriata), have played a critical role in the transition from water to land. Hibernation is a vital survival adaptation in cold environments with limited food resources.
Yunyun Lv, Chuan Chen, Chengzhi Yan, Wenbo Liao   +3 more
doaj   +1 more source

Single‐Cell Nanodroplet Processing Proteomics Pipeline for Analysis of Human‐Derived Microglia

PROTEOMICS, EarlyView.
ABSTRACT Single‐cell omics tools provide unique insights into heterogeneous cell populations and their responses to stimuli. For example, single‐cell RNA sequencing has identified several transcriptionally distinct populations of microglia, which are resident immune cells of the central nervous system (CNS) that are responsive to CNS injury, infection,
Ashley N. Ives, James M. Fulcher, Alex R. Bautista, Reta Birhanu Kitata, Sarah M. Williams, David A. Bennett, Philip L. De Jager, Vladislav A. Petyuk   +7 more
wiley   +1 more source

In Vivo Autophagy Up-Regulation of Small Intestine Enterocytes in Chinese Soft-Shelled Turtles during Hibernation

Biomolecules, 2019
Many studies have focused on how autophagy plays an important role in intestinal homeostasis under pathological conditions. However, its role in the intestine during hibernation remains unclear.
Waseem Ali Vistro, Yue Zhang, Xuebing Bai, Ping Yang, Yufei Huang, Wenjia Qu, Abdul Sattar Baloch, Ruizhi Wu, Imran Tarique, Qiusheng Chen   +9 more
doaj   +1 more source

Seasonal body mass dynamics mediate life-history trade-offs in a hibernating mammal. [PDF]

J Anim Ecol
We tested a suite of ecological hypotheses to explain variation in seasonal body mass dynamics of a fat‐storing mammalian hibernator. We further demonstrated that pre‐hibernation mass gain in ground squirrels mediates an annual allocation trade‐off between current and future reproduction as the squirrels forage and rear young under predation risk ...
Allison AZT, Conway CJ, Goldberg AR, Morris AE, Hakanson EC.   +4 more
europepmc   +2 more sources

The European honey buzzard (Pernis apivorus) as an ally for the control of the invasive yellow‐legged hornet (Vespa velutina nigrithorax)

Pest Management Science, Volume 81, Issue 4, Page 2237-2247, April 2025.
The predatory effect of the honey‐buzzard affects the reproductive performance of Asian‐hornet colonies, decreasing the density of workers over distance and time. The foraging distances of the honey‐buzzard concentrates within the first 2000 m from nest, which supports the results observed.
Jorge Ángel Martín‐Ávila, Luisa María Díaz‐Aranda, José Manuel Fernández‐Pereira, Salvador Rebollo   +3 more
wiley   +1 more source

Expressions of TLR4, MyD88, IRAK4 and NF-κΒ in the oviduct of Chinese brown frog (Rana dybowskii)

European Journal of Histochemistry, 2019
One special physiological phenomenon of the Chinese brown frog (Rana dybowskii) is that its oviduct goes through expansion prior to pre-hibernation instead of expanding during the breeding period. Our previous study discovered that some cytokines such as
Yue Zhang, Ao Zhang, Yue Zhao, Xiaohang Feng, Yuyao Sheng, Haolin Zhang, Qiang Weng, Meiyu Xu   +7 more
doaj   +1 more source

Hunting, but not outdoor recreation, modulates behavioural tolerance to human disturbance in Alpine marmots Marmota marmota

Wildlife Biology, EarlyView.
Humans are often perceived as predators by free‐living animals, and thus, even non‐consumptive human activities such as outdoor recreation may trigger behavioural and physiological responses, often with negative consequences on individual fitness and population persistence.
Friederike Zenth, Chiara Giari, Elena Morocutti, Ilse Storch, Daniel T. Blumstein, Andrea Corradini, Davide Righetti, Dominik Trenkwalder, Luca Corlatti   +8 more
wiley   +1 more source