Results 51 to 60 of about 569,916 (267)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Hierarchical and Non-Hierarchical Triples [PDF]

Symposium - International Astronomical Union, 1996
Triple stars and galaxies are referred to as having hierarchical or non-hierarchical structure. Thus, the dynamically stable and unstable triple systems are usually distinguished observationally by the ratio of the larger and smaller angular separation.
J. Anosova, L. Kiseleva, P. Eggleton, V. Orlov   +3 more
openaire   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Enantiomeric Ratio Modulates Hierarchical Networks and Rheological Performance in Cyclohexane Bisurea Supramolecular Gels

Gels
This study presents an enantiomeric-ratio-driven strategy for constructing mechanically robust supramolecular gels using cyclohexane bisurea derivatives.
Shaoshuai Hua, Yuqian Jiang, Andong Song, Jian Jiang   +3 more
doaj   +1 more source

Hierarchical Unambiguity

SIAM Journal on Computing, 2006
We develop techniques to investigate relativized hierarchical unambiguous computation. We apply our techniques to generalize known constructs involving relativized unambiguity based complexity classes (UP and \mathcal{UP}) to new constructs involving arbitrary higher levels of the relativized unambiguous polynomial hierarchy (UPH).
Holger Spakowski, Rahul Tripathi
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Characterization of High-Temperature Hierarchical Porous Mullite Washcoat Synthesized Using Aluminum Dross and Coal Fly Ash

Crystals, 2020
Mixture of aluminum dross (AD) and coal fly ash (CFA) was used to produce high-temperature porous mullite for washcoat application. CFA is the combustion by-product of pulverized coal in a coal-fired power plant, while AD is a waste product produced in ...
Thye Foo Choo, Mohamad Amran Mohd Salleh, Kuan Ying Kok, Khamirul Amin Matori, Suraya Abdul Rashid   +4 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

High‑Temperature Image Pre‐Processing Based on ε‐Ga2O3 Photo‐Synapses

Advanced Physics Research
The era of big data has brought about substantial challenges in terms of power consumption and communication bandwidth. Edge‐based neuromorphic computing with data pre‐processing can help alleviate these burdens and enhance overall system efficiency ...
Yingtong Lin, Yuhan Zhu, Feng Wang, Yuchen Cai, Zhengqiao Li, Shuhui Li, Xueying Zhan, Jun He, Chao Jiang, Zhenxing Wang   +9 more
doaj   +1 more source

Multidimensional Security Provision for Secure Communication in Vehicular Ad Hoc Networks Using Hierarchical Structure and End-to-End Authentication

IEEE Access, 2018
Vehicular ad hoc networks (VANETs) have been considered as one of the most influential applications of mobile ad hoc networks. The VANETs have also become an important part of Internet of Things.
Gulshan Kumar, Rahul Saha, Mritunjay Kumar Rai, Tai-Hoon Kim   +3 more
doaj   +1 more source