Results 71 to 80 of about 26,331 (262)

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

Advanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

Computational Identification of MoRFs in Protein Sequences Using Hierarchical Application of Bayes Rule.

PLoS ONE, 2015
MotivationIntrinsically disordered regions of proteins play an essential role in the regulation of various biological processes. Key to their regulatory function is often the binding to globular protein domains via sequence elements known as molecular ...
Nawar Malhis, Eric T C Wong, Roy Nassar, Jörg Gsponer   +3 more
doaj   +1 more source

Freedom dreaming of migrant justice: Critical reflections on counterspaces and institutional violence in the university

American Journal of Community Psychology, EarlyView.
Abstract US universities are built on stolen land and sustained through hierarchies of power that produce what migrant justice scholars name as b/order regimes. As institutions that claim to be sites of learning and inclusion, universities are fraught with contradictions as simultaneously sites of dispossession, exclusion, and control.
Sara L. Buckingham, Jesica Siham Fernández   +1 more
wiley   +1 more source

Hyperspectral Image Restoration under Complex Multi-Band Noises

Remote Sensing, 2018
Hyperspectral images (HSIs) are always corrupted by complicated forms of noise during the acquisition process, such as Gaussian noise, impulse noise, stripes, deadlines and so on.
Zongsheng Yue, Deyu Meng, Yongqing Sun, Qian Zhao   +3 more
doaj   +1 more source

Sheep Horn Development Revealed by Multi‐Tissue and Cross‐Species Transcriptomic Analysis

Animal Research and One Health, EarlyView.
Multi‐tissue and cross‐species transcriptomics with allele‐specific expression show sheep horns are a composite organ integrating epidermal and osteogenic programs. Conserved horn gene modules and cis‐regulatory variation fine‐tune expression networks underlying horn development and size (small scurs vs. large spiral horns).
Hao Li, Yuchen He, Yangshuo Hu, Naominggaowa, Huaiqiang Yang, Zhu Meng, Fei Liu, Shiwen Zhang, Yi Jin, Mingxing Chu, Zhangyuan Pan   +10 more
wiley   +1 more source

Identifying Systemic Lupus Erythematosus From Serum Proteomic Profiles Using Machine Learning and Genetic Risk Stratification

Arthritis &Rheumatology, EarlyView.
Objective Proteome‐wide risk models for lupus remain underexplored. We developed classification models to identify lupus from serum proteomic profiles. Methods Patients with lupus and individuals with other autoimmune diseases in the UK Biobank were included.
Mehmet Hocaoǧlu, Jishnu Das, Amr H. Sawalha   +2 more
wiley   +1 more source

Comparing Hierarchical Approaches to Enhance Supervised Emotive Text Classification

Big Data and Cognitive Computing
The performance of emotive text classification using affective hierarchical schemes (e.g., WordNet-Affect) is often evaluated using the same traditional measures used to evaluate the performance of when a finite set of isolated classes are used. However,
Lowri Williams, Eirini Anthi, Pete Burnap   +2 more
doaj   +1 more source

Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments

BMC Bioinformatics, 2006
Background The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently.
Wesselkamper Scott C, Tomlinson Craig R, Sartor Maureen A, Sivaganesan Siva, Leikauf George D, Medvedovic Mario   +5 more
doaj   +1 more source

Using Auxiliary Item Information in the Item Parameter Estimation of a Graded Response Model for a Small to Medium Sample Size: Empirical Versus Hierarchical Bayes Estimation. [PDF]

Appl Psychol Meas, 2023
Naveiras M, Cho SJ.
europepmc   +1 more source

Efficacy and Safety of Nanoencapsulated Sirolimus Plus Pegadricase: Results From the Randomized, Placebo‐Controlled Phase 3 Trials

Arthritis &Rheumatology, EarlyView.
Objective DISSOLVE I and II examined the efficacy and safety of nanoencapsulated sirolimus (NAS) plus pegadricase (NASP) in patients with uncontrolled gout (UG). Methods In these double‐blind, placebo‐controlled Phase 3 trials of NASP, patients were randomized 1:1:1 to infusions of high‐dose (HD) or low‐dose (LD) NAS plus pegadricase (HD NASP, LD NASP,
Herbert S. B. Baraf, Puja P. Khanna, Milan Petronijevic, Mamuka Lortkipanidze, Anand Patel, Kwabena Ayesu, Michael H. Pillinger, Atul Singhal, Joanna Sobierska, Jacquie Christie, Peter Traber, Rehan Azeem, Wesley DeHaan, Hugues Santin‐Janin, Bhavisha Desai, Alan Kivitz   +15 more
wiley   +1 more source