Results 91 to 100 of about 3,381,889 (354)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Hierarchical Clustering better than Average-Linkage [PDF]

ACM-SIAM Symposium on Discrete Algorithms, 2018
Hierarchical Clustering (HC) is a widely studied problem in exploratory data analysis, usually tackled by simple agglomerative procedures like average-linkage, single-linkage or complete-linkage.
M. Charikar, Vaggos Chatziafratis, Rad Niazadeh   +2 more
semanticscholar   +1 more source

Clustering Scatter Plots Using Data Depth Measures. [PDF]

, 2011
Clustering is rapidly becoming a powerful data mining technique, and has been broadly applied to many domains such as bioinformatics and text mining. However, the existing methods can only deal with a data matrix of scalars. In this paper, we introduce a
Borneman, James, Braun, Jonathan, Cui, Xinping, Jeske, Daniel R, Li, Xiaoxiao, Zhang, Zhanpan   +5 more
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Assessment of Heart Disease using Fuzzy Classification Techniques

The Scientific World Journal, 2001
In this paper we discuss the classification results of cardiac patients of ischemical cardiopathy, valvular heart disease, and arterial hypertension, based on 19 characteristics (descriptors) including ECHO data, effort testings, and age and weight.
Horia F. Pop, Tudor L. Pop, Costel Sarbu
doaj   +1 more source

Nonparametric Hierarchical Clustering of Functional Data

, 2014
In this paper, we deal with the problem of curves clustering. We propose a nonparametric method which partitions the curves into clusters and discretizes the dimensions of the curve points into intervals.
C. Abraham, D.M. Blei, F. Chamroukhi, G. Delaigle, G. Hébrail, J. Rissanen, M. Abramowitz, P. Hansen, R.M. Neal, T. Cover, T. Gasser, X. Nguyen   +11 more
core   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Solving non-uniqueness in agglomerative hierarchical clustering using multidendrograms

, 2009
In agglomerative hierarchical clustering, pair-group methods suffer from a problem of non-uniqueness when two or more distances between different clusters coincide during the amalgamation process.
A.D. GORDON, Alberto Fernández, B.J.T. MORGAN, G. HART, G.J. SZÉKELY, G.N. LANCE, J. MACCUISH, J.H. WARD Jr., P.H.A. SNEATH, R.M. CORMACK, Sergio Gómez, T. BACKELJAU, V. ARNAU, W.A. KLOOT VAN DER   +13 more
core   +2 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Mobility-Aware Hierarchical Clustering in Mobile Wireless Sensor Networks

IEEE Access, 2019
Wireless sensor networks (WSNs) are one of the chief enabling technologies for the Internet of Things. These networks are severely resource-constrained which calls for designing energy-efficient and effective routing techniques.
S. Zafar, Abeer Bashir, S. A. Chaudhry
semanticscholar   +1 more source