Results 41 to 50 of about 195,286 (257)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Cogent Business & Management, 2019 Corporations undergo growth, maturity and decline, stages which form the corporate life cycle. This study discusses the influence of group, firm and time effects on enterprise performance variation at the different life cycle stages of Taiwan’s ...
Chiau-Shi Yang, Jonchi Shyu
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Estimation Quality and Required Sample Sizes in Three-Level Contextual Analysis Models
Methodology, 2023 In multilevel analysis, Level-1 predictors that also explain variance at a higher level are called contextual predictors. In the multilevel manifest covariate model, the Level-2 component is modeled as the average of the Level-1 predictor scores within a
Denny Kerkhoff, Fridtjof W. Nussbeck
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Journal of MathematicsBoth frequentist and Bayesian statistics schools have improved statistical tools and model choices for the collected data or measurements. Model selection approaches have advanced due to the difficulty of comparing complicated hierarchical models in ...
Endris Assen Ebrahim +2 more
doaj +1 more source
Frontiers in Plant Science, 2020 The accuracy of nitrogen (N) diagnosis is essential to improve N use efficiency. The standard critical N concentration (standard Nc) dilution curves, an expression of the dynamics of N uptake and dry matter accumulation in plants, are widely used to ...
Yu Zhao +9 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
A Correlation Analysis-Based Hierarchical Identification Strategy for Hammerstein Models
AlgorithmsReliable mathematical models are essential for high-performance analysis and optimization of complex power and energy systems. However, inherent nonlinearities pose significant challenges to accurate model identification. The Hammerstein model, a typical
Qi Dong +3 more
doaj +1 more source
Prediction of Wheat Grain Protein by Coupling Multisource Remote Sensing Imagery and ECMWF Data
Remote Sensing, 2020 Industrialization production with high quality and effect on winter is an important measure for accelerating the shift from increasing agricultural production to improving quality in terms of grain protein content (GPC).
Xiaobin Xu +11 more
doaj +1 more source