Results 31 to 40 of about 9,625,516 (256)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

A Hierarchical Linear Models Approach to Explaining Reflective Thinking Skill Through Problem Solving

Anadolu Üniversitesi Eğitim Fakültesi dergisi
The purpose of this study is to identify the student and teacher level factors that explain the reflective thinking skills through problem solving of elementary school pupils. The research was conducted in public elementary schools in three Van districts:
Gürol Zırhlıoğlu, Osman Tat
doaj   +1 more source

Heterogeneity among contingency tables diagnosed by hierarchical log-linear models and their effect on Biplots

Semina: Ciências Exatas e Tecnológicas, 2022
The theory of singular value decomposition of matched matrices is used to verify the heterogeneity of rows, columns and between matched two-way tables.
Carla Regina Guimarães Brighenti, Daniela Aparecida Mafra, Marcelo Angelo Cirillo   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Generalized linear models [PDF]

, 1972
The technique of iterative weighted linear regression can be used to obtain maximum likelihood estimates of the parameters with observations distributed according to some exponential family and systematic effects that can be made linear by a suitable ...
Nelder, J. A., Wedderburn, R. W. M.
core   +1 more source

Macroeconomic and Institutional Factors, Debt Composition and Capital Structure of Latin American Companies

BBR: Brazilian Business Review, 2018
The objective of this research was to examine the influence of macroeconomic and institutional factors when determining the capital structure of Latin American companies from 2009 to 2014, and also analyze if the significance of these factors to explain ...
Cláudio Bernardo, Tatiana Albanez, José Roberto Securato   +2 more
doaj   +1 more source

Spatial Patterns of Production-Distribution-Consumption Cycle: The Specifics of Developing Russia

Economies, 2020
The existing body of academic literature reveals that production, distribution, and consumption might be both consistently connected and geographically scattered.
Venera Timiryanova, Konstantin Grishin, Dina Krasnoselskaya   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Hierarchical models, marginal polytopes, and linear codes [PDF]

, 2009
summary:In this paper, we explore a connection between binary hierarchical models, their marginal polytopes, and codeword polytopes, the convex hulls of linear codes. The class of linear codes that are realizable by hierarchical models is determined.
Wenzel, Walter, Wenzel, W., Ay, N., Kahle, Thomas, Ay, Nihat, Kahle, T.   +5 more
core   +1 more source

Hierarchical Generalized Linear Models: The R Package HGLMMM

Journal of Statistical Software, 2011
The R package HGLMMM has been developed to fit generalized linear models with random effects using the h-likelihood approach. The response variable is allowed to follow a binomial, Poisson, Gaussian or gamma distribution.
Marek Molas, Emmanuel Lesaffre
doaj