Results 51 to 60 of about 337,305 (266)

A hierarchical model of metacognition. [PDF]

open access: yes, 2020
I present a novel method of conceptualizing metacognition in a computational hierarchy. Metacognition is commonlydescribed as cognition acting on itself, and correlates with enhanced performance in memory, reasoning, emotional reg-ulation, and motor skills.
Conway-Smith, Brendan, West, Robert
openaire   +1 more source

Hierarchical Variational Models

open access: yesCoRR, 2015
Appears in International Conference on Machine Learning ...
Rajesh Ranganath   +2 more
openaire   +3 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Spatially prioritizing mitigation for amphibian roadkills based on fatality estimation and landscape conversion

open access: yesFrontiers in Ecology and Evolution, 2023
Roads cause biodiversity loss and the effects of wildlife-vehicle collisions may ripple from individuals and populations to ecosystem functioning. Amphibians are threatened worldwide and, despite being particularly prone to roadkill impacts, they are ...
Larissa Oliveira Gonçalves   +10 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

A class of admissible estimators of multiple regression coefficient with an unknown variance

open access: yesStatistical Theory and Related Fields, 2020
Suppose that we observe ${\boldsymbol y} \mid {\boldsymbol \theta },\ \tau \sim N_p({\boldsymbol X}{\boldsymbol \theta },\tau ^{-1}{\boldsymbol I}_p) $, where ${\boldsymbol \theta } $ is an unknown vector with unknown precision τ.
Chengyuan Song, Dongchu Sun
doaj   +1 more source

Hierarchical Causal Models [PDF]

open access: yesJ. Mach. Learn. Res.
75 pages, 29 figures.
Weinstein, Eli N., Blei, David M.
openaire   +3 more sources

Dynamic Hierarchical Factor Models [PDF]

open access: yesSSRN Electronic Journal, 2011
AbstractThis paper uses multilevel factor models to characterize within- and between-block variations as well as idiosyncratic noise in large dynamic panels. Block-level shocks are distinguished from genuinely common shocks, and the estimated block-level factors are easy to interpret. The framework achieves dimension reduction and yet explicitly allows
Emanuel Moench   +2 more
openaire   +4 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Key Habitat and Predatory Influences on the Community- and Species-Level Population Dynamics of Spring-Breeding Amphibian Larvae Within a Remnant Tupelo-Cypress Wetland

open access: yesHydrobiology
Understanding the factors influencing amphibian populations is essential for effective freshwater conservation, particularly for species with biphasic life histories.
Jacob M. Hutton, Robin W. Warne
doaj   +1 more source

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