Results 71 to 80 of about 399,077 (314)

Hierarchical Causal Models [PDF]

J. Mach. Learn. Res.
75 pages, 29 figures.
Weinstein, Eli N., Blei, David M.
openaire   +3 more sources

Dynamic Hierarchical Factor Models [PDF]

SSRN Electronic Journal, 2011
AbstractThis paper uses multilevel factor models to characterize within- and between-block variations as well as idiosyncratic noise in large dynamic panels. Block-level shocks are distinguished from genuinely common shocks, and the estimated block-level factors are easy to interpret. The framework achieves dimension reduction and yet explicitly allows
Emanuel Moench, Serena Ng, Simon M. Potter   +2 more
openaire   +4 more sources

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Kernel-Based Learning of Hierarchical Multilabel Classification Models [PDF]

, 2006
We present a kernel-based algorithm for hierarchical text classification where the documents are allowed to belong to more than one category at a time.
Szedmak, S., Shawe-Taylor, J., Rousu, J., Saunders, C.   +3 more
core  

Large positive ecological changes of small urban greening actions

Ecological Solutions and Evidence, 2023
The detrimental effects of environmental change on human and non‐human diversity are acutely manifested in urban environments. While urban greenspaces are known to mitigate these effects and support functionally diverse ecological communities, evidence ...
Luis Mata, Amy K. Hahs, Estibaliz Palma, Anna Backstrom, Nikolas Johnston, Tyler King, Ashley R. Olson, Christina Renowden, Tessa R. Smith, Blythe Vogel, Samantha Ward   +10 more
doaj   +1 more source

Hierarchical Reasoning Model

CoRR
Reasoning, the process of devising and executing complex goal-oriented action sequences, remains a critical challenge in AI. Current large language models (LLMs) primarily employ Chain-of-Thought (CoT) techniques, which suffer from brittle task decomposition, extensive data requirements, and high latency.
Guan Wang, Jin Li, Yuhao Sun, Xing Chen, Changling Liu, Yue Wu, Meng Lu, Sen Song, Yasin Abbasi-Yadkori   +8 more
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

A hierarchical multi-label classification ant colony algorithm for protein function prediction [PDF]

, 2010
This paper proposes a novel ant colony optimisation (ACO) algorithm tailored for the hierarchical multi-label classification problem of protein function prediction.
Otero, Fernando E.B., Colin G. Johnson, Johnson, Colin G., Alex A. Freitas, Freitas, Alex A., Fernando E. B. Otero   +5 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Bringing circuit theory into spatial occupancy models to assess landscape connectivity

Methods in Ecology and Evolution
Occupancy models were originally developed to better understand species distribution while accounting for imperfect detection. Because species distribution is not only shaped by habitat quality but also by the ability of individuals to reach suitable ...
Maëlis Kervellec, Thibaut Couturier, Sarah Bauduin, Delphine Chenesseau, Pierre Defos du Rau, Nolwenn Drouet‐Hoguet, Christophe Duchamp, Julien Steinmetz, Jean‐Michel Vandel, Olivier Gimenez   +9 more
doaj   +1 more source