Results 71 to 80 of about 1,044,365 (214)

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Bringing circuit theory into spatial occupancy models to assess landscape connectivity

Methods in Ecology and Evolution
Occupancy models were originally developed to better understand species distribution while accounting for imperfect detection. Because species distribution is not only shaped by habitat quality but also by the ability of individuals to reach suitable ...
Maëlis Kervellec, Thibaut Couturier, Sarah Bauduin, Delphine Chenesseau, Pierre Defos du Rau, Nolwenn Drouet‐Hoguet, Christophe Duchamp, Julien Steinmetz, Jean‐Michel Vandel, Olivier Gimenez   +9 more
doaj   +1 more source

bamdit: An R Package for Bayesian Meta-Analysis of Diagnostic Test Data

Journal of Statistical Software, 2018
In this paper we present the R package bamdit. The name of the package stands for "Bayesian meta-analysis of diagnostic test data". bamdit was developed with the aim of simplifying the use of models in meta-analysis, that up to now have demanded great ...
Pablo Emilio Verde
doaj   +1 more source

Articulated Pose Estimation Using Hierarchical Exemplar-Based Models

, 2015
Exemplar-based models have achieved great success on localizing the parts of semi-rigid objects. However, their efficacy on highly articulated objects such as humans is yet to be explored.
Allen, Peter, Belhumeur, Peter, Li, Yinxiao, Liu, Jiongxin   +3 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Accurately Estimating Correlations Between Demographic Parameters: A Response to Riecke Et al. (2024)

Ecology and Evolution
Correlations between annual recovery and survival probabilities estimated from tag‐recovery data have been used to quantify the demographic response of exploited populations to harvest. Deane et al.
Cody E. Deane, Lindsay G. Carlson, Curry J. Cunningham, Pat Doak, Knut Kielland, Greg A. Breed   +5 more
doaj   +1 more source

A Novel Approach to Improve the Estimation of a Diet Adherence Considering Seasonality and Short Term Variability – The NU-AGE Mediterranean Diet Experience

Frontiers in Physiology, 2019
In this work we present a novel statistical approach to improve the assessment of the adherence to a 1-year nutritional intervention within the framework of the NU-AGE project. This was measured with a single adherence score based on 7-days food records,
Enrico Giampieri, Rita Ostan, Giulia Guidarelli, Stefano Salvioli, Agnes A. M. Berendsen, Anna Brzozowska, Barbara Pietruszka, Amy Jennings, Nathalie Meunier, Elodie Caumon, Susan Fairweather-Tait, Ewa Sicinska, Edith J. M. Feskens, Lisette C. P. G. M. de Groot, Claudio Franceschi, Aurelia Santoro, Aurelia Santoro   +16 more
doaj   +1 more source

Effects of camera‐trap placement and number on detection of members of a mammalian assemblage

Ecosphere, 2021
A central goal in camera‐trapping (CT) studies is to maximize detection probability and precision of occupancy estimates while minimizing the number of CTs to reduce equipment and labor costs.
Tim R. Hofmeester, Neri H. Thorsen, Joris P. G. M. Cromsigt, Jonas Kindberg, Henrik Andrén, John D. C. Linnell, John Odden   +6 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

SOMTreeNet: A Hybrid Topological Neural Model Combining Self-Organizing Maps and BIRCH for Structured Learning

Mathematics
This study introduces SOMTreeNet, a novel hybrid neural model that integrates Self-Organizing Maps (SOMs) with BIRCH-inspired clustering features to address structured learning in a scalable and interpretable manner.
Yunus Doğan
doaj   +1 more source