Results 131 to 140 of about 387,064 (296)

Nurr1 Orchestrates Claustrum Development and Functionality

open access: yesAdvanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan   +12 more
wiley   +1 more source

Robotic Materials With Bioinspired Microstructures for High Sensitivity and Fast Actuation

open access: yesAdvanced Science, EarlyView.
In the review paper, design rationale and approaches for bioinspired sensors and actuators in robotics applications are presented. These bioinspired microstructure strategies implemented in both can improve the performance in several ways. Also, recent ideas and innovations that embed robotic materials with logic and computation with it are part of the
Sakshi Sakshi   +4 more
wiley   +1 more source

Hierarchical reinforcement learning for spoken dialogue systems [PDF]

open access: yes, 2009
This thesis focuses on the problem of scalable optimization of dialogue behaviour in speech-based conversational systems using reinforcement learning. Most previous investigations in dialogue strategy learning have proposed flat reinforcement learning methods, which are more suitable for small-scale spoken dialogue systems. This research formulates the
openaire   +3 more sources

Wedelolactone, a Novel TLR2 Agonist, Promotes Neutrophil Differentiation and Ameliorates Neutropenia: A Multi‐Omics Approach to Unravel the Mechanism

open access: yesAdvanced Science, EarlyView.
Wedelolactone (WED), a natural TLR2 agonist, promotes neutrophil differentiation and enhances bactericidal function, offering a potential therapeutic strategy for neutropenia. Using a multi‐omics approach, this study reveals that WED activates the TLR2/MEK/ERK pathway, upregulating key transcription factors (PU.1, CEBPβ) to drive neutrophil development.
Long Wang   +16 more
wiley   +1 more source

Hierarchical Reinforcement Learning Based Resource Allocation for RAN Slicing

open access: yesIEEE Access
As the complexity of wireless mobile networks increases significantly, artificial intelligence (AI) and machine learning (ML) have become key enablers for radio resource management and orchestration.
Hasan Anil Akyildiz   +3 more
doaj   +1 more source

Hierarchical Object Detection with Deep Reinforcement Learning

open access: yes, 2017
This work introduces a model for Hierarchical Object Detection with Deep Reinforcement Learning (HOD-DRL). The key idea is to focus on those parts of the image that contain richer information and zoom on them. We train an intelligent agent that, given an image window, is capable of deciding where to focus the attention on five different predefined ...
Bellver, Míriam   +3 more
openaire   +5 more sources

Navigating the Ethereal Tightrope: The Nanogenerator Manipulates Neurons for Immune Equilibrium

open access: yesAdvanced Science, EarlyView.
This review explores how nanogenerators modulate neuroimmune responses, offering innovative strategies for treating neurological disorders. By interfacing with neural pathways, they enable precise control of immune activity, especially via vagus nerve stimulation.
Jia Du   +5 more
wiley   +1 more source

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