Results 41 to 50 of about 275,491 (268)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Recovery Strategy of Distribution Network Based on Power Supply Capability Assessment of Local Area Configured with Energy Gateway

Energies
The growing integration of DG enhances distribution network resilience, but existing centralized fault recovery strategies face critical limitations: excessive computational burdens on DCs and the insufficient utilization of local control capabilities ...
Xiaoxia Guo, Weijia Guo, Xiang Jiang, Wei Wang, Junpeng Zhu   +4 more
doaj   +1 more source

Hierarchical control system for a flexible microgrid with dynamic boundary: design, implementation and testing

IET Smart Grid, 2019
The design, implementation, and testing of a control system for a flexible microgrid (MG) is presented in this study. The MG controllers can be implemented in a real-world MG with multiple smart switches, photovoltaic panel system, and battery energy ...
He Yin, Yiwei Ma, Lin Zhu, Xiaotong Hu, Yu Su, Jim Glass, Fred Wang, Yilu Liu, Leon M. Tolbert   +8 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Expert Evaluation of the Significance of Criteria for Electric Vehicle Deployment: A Case Study of Lithuania

Smart Cities
This study presents the hierarchical structure of 50 sub-criteria divided into 7 main criteria for the assessment of electric vehicle (EV) deployment.
Henrikas Sivilevičius, Vidas Žuraulis, Justas Bražiūnas   +2 more
doaj   +1 more source

Hierarchical medical system and local medical performance: A quasi-natural experiment evaluation in Shanghai, China

Frontiers in Public Health, 2022
BackgroundIn order to maintain high standards of healthcare, it is necessary for medical departments to provide high-quality and affordable medical services to local residents.
Chen Liang, Yihang Zhao, Chenglong Yu, Peng Sang, Long Yang   +4 more
doaj   +1 more source

On hierarchically developing reactive systems

Information and Computation, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Zhan, Naijun, Majster-Cederbaum, Mila
openaire   +3 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Order reduction of hierarchical interconnected dynamical systems [PDF]

Advances in Radio Science, 2018
The simulation of large scale nonlinear dynamical interconnected systems, as they arise in all modern engineering disciplines, is a usual task. Due to the high complexity of the considered systems, the principle of thinking in hierarchical structures ...
M. Popp, W. Mathis
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source