Results 51 to 60 of about 9,650,037 (303)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Interpretability indices for hierarchical fuzzy systems [PDF]

open access: yes, 2017
Hierarchical fuzzy systems (HFSs) have been shown to have the potential to improve interpretability of fuzzy logic systems (FLSs). In recent years, a variety of indices have been proposed to measure the interpretability of FLSs such as the Nauck index ...
T. R. Razak   +15 more
core   +1 more source

Chiral gold nanoparticles enantioselectively rescue memory deficits in a mouse model of Alzheimer’s disease

open access: yesNature Communications, 2020
Nanoparticles are being explored as a potential method to target Aβ aggregation in Alzheimer’s disease. Here, the authors develop gold nanoparticles that were capped with chiral L or D-glutathione which has been shown to improve BBB permeability and ...
Ke Hou   +14 more
doaj   +1 more source

Systems of Systems Modeled by a Hierarchical Part-Whole State-Based Formalism [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2013
The paper presents an explicit state-based modeling approach aimed at modeling Systems of Systems behavior. The approach allows to specify and verify incrementally safety and liveness rules without using model checking techniques.
Luca Pazzi
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Improving Broadcast Channel Rate Using Hierarchical Modulation [PDF]

open access: yes, 2012
We investigate the design of a broadcast system where the aim is to maximise the throughput. This task is usually challenging due to the channel variability.
Méric, Hugo   +4 more
core  

Recovery Strategy of Distribution Network Based on Power Supply Capability Assessment of Local Area Configured with Energy Gateway

open access: yesEnergies
The growing integration of DG enhances distribution network resilience, but existing centralized fault recovery strategies face critical limitations: excessive computational burdens on DCs and the insufficient utilization of local control capabilities ...
Xiaoxia Guo   +4 more
doaj   +1 more source

Hierarchical control system for a flexible microgrid with dynamic boundary: design, implementation and testing

open access: yesIET Smart Grid, 2019
The design, implementation, and testing of a control system for a flexible microgrid (MG) is presented in this study. The MG controllers can be implemented in a real-world MG with multiple smart switches, photovoltaic panel system, and battery energy ...
He Yin   +8 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Expert Evaluation of the Significance of Criteria for Electric Vehicle Deployment: A Case Study of Lithuania

open access: yesSmart Cities
This study presents the hierarchical structure of 50 sub-criteria divided into 7 main criteria for the assessment of electric vehicle (EV) deployment.
Henrikas Sivilevičius   +2 more
doaj   +1 more source

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